2022
Dietary omega-3 fatty acids and endometrial cancer risk in the Epidemiology of Endometrial Cancer Consortium: An individual-participant meta-analysis
Brasky T, Hade E, Cohn D, Newton A, Petruzella S, O'Connell K, Bertrand K, Cook L, De Vivo I, Du M, Freudenheim J, Friedenreich C, Goodman M, Gorzelitz J, Ibiebele T, Krogh V, Liao L, Lipworth L, Lu L, McCann S, O'Mara T, Palmer J, Ponte J, Prizment A, Risch H, Sandin S, Schouten L, Setiawan V, Shu X, Trabert B, van den Brandt P, Webb P, Wentzensen N, Wilkens L, Wolk A, Yu H, Neuhouser M. Dietary omega-3 fatty acids and endometrial cancer risk in the Epidemiology of Endometrial Cancer Consortium: An individual-participant meta-analysis. Gynecologic Oncology 2022, 169: 137-146. PMID: 36934308, PMCID: PMC10025515, DOI: 10.1016/j.ygyno.2022.10.015.Peer-Reviewed Original ResearchConceptsEndometrial cancer riskEndometrial Cancer ConsortiumHigh dietary intakeCancer riskDietary intakeObese womenOdds ratioCancer ConsortiumDietary omega-3 fatty acidsOmega-3 fatty acidsEnergy-adjusted quartilesEndometrial cancer casesEndometrial cancer incidenceProspective cohort studyFood frequency questionnaireNormal-weight womenFatty acid intakeAdjusted odds ratioBody mass indexLong-chain omega-3Anti-inflammatory propertiesSubgroup of womenConfidence intervalsCase-control studyTwo-stage individual participant data
2015
Dietary flavonoid intake and Barrett's esophagus in western Washington State
Petrick JL, Steck SE, Bradshaw PT, Chow WH, Engel LS, He K, Risch HA, Vaughan TL, Gammon MD. Dietary flavonoid intake and Barrett's esophagus in western Washington State. Annals Of Epidemiology 2015, 25: 730-735.e2. PMID: 26169148, PMCID: PMC4567908, DOI: 10.1016/j.annepidem.2015.05.010.Peer-Reviewed Original ResearchConceptsOdds of BESpecialized intestinal metaplasiaBarrett's esophagusOdds ratioIntestinal metaplasiaInverse associationPrecursor lesionsWestern Washington StateDietary flavonoid intakeDecreased odds ratioFood frequency questionnaireAdequate dietary intakeBody mass indexCase-control investigationCancer precursor lesionsCase-control study participantsDietary sourcesLogistic regression modelsFlavonoid classesMain dietary sourceAnthocyanidin intakeFrequency questionnaireFlavonoid intakeMass indexIsoflavone intakeDietary intake of flavonoids and oesophageal and gastric cancer: incidence and survival in the United States of America (USA)
Petrick JL, Steck SE, Bradshaw PT, Trivers KF, Abrahamson PE, Engel LS, He K, Chow WH, Mayne ST, Risch HA, Vaughan TL, Gammon MD. Dietary intake of flavonoids and oesophageal and gastric cancer: incidence and survival in the United States of America (USA). British Journal Of Cancer 2015, 112: 1291-1300. PMID: 25668011, PMCID: PMC4385952, DOI: 10.1038/bjc.2015.25.Peer-Reviewed Original ResearchConceptsOdds ratioHazard ratioFlavonoid intakeGastric cancerFood frequency questionnaire responsesMulticentre population-based studyIntake of anthocyanidinsLowest intake quartilesTotal flavonoid intakeFrequency-matched controlsPopulation-based studyProportional hazards regressionRisk of mortalityUSDA flavonoid databasesCase participantsAnthocyanidin intakeIntake quartilesHazards regressionVital statusDietary intakeChemopreventive effectsEpidemiologic studiesTumor typesFlavonoid databaseCancer
2014
Consortium analysis of gene and gene–folate interactions in purine and pyrimidine metabolism pathways with ovarian carcinoma risk
Kelemen LE, Terry KL, Goodman MT, Webb PM, Bandera EV, McGuire V, Rossing MA, Wang Q, Dicks E, Tyrer JP, Song H, Kupryjanczyk J, Dansonka‐Mieszkowska A, Plisiecka‐Halasa J, Timorek A, Menon U, Gentry‐Maharaj A, Gayther SA, Ramus SJ, Narod SA, Risch HA, McLaughlin JR, Siddiqui N, Glasspool R, Paul J, Carty K, Gronwald J, Lubiński J, Jakubowska A, Cybulski C, Kiemeney LA, Massuger LF, van Altena A, Aben KK, Olson SH, Orlow I, Cramer DW, Levine DA, Bisogna M, Giles GG, Southey MC, Bruinsma F, Kjær S, Høgdall E, Jensen A, Høgdall CK, Lundvall L, Engelholm S, Heitz F, du Bois A, Harter P, Schwaab I, Butzow R, Nevanlinna H, Pelttari LM, Leminen A, Thompson PJ, Lurie G, Wilkens LR, Lambrechts D, Van Nieuwenhuysen E, Lambrechts S, Vergote I, Beesley J, Investigators A, Fasching P, Beckmann M, Hein A, Ekici A, Doherty J, Wu A, Pearce C, Pike M, Stram D, Chang‐Claude J, Rudolph A, Dörk T, Dürst M, Hillemanns P, Runnebaum I, Bogdanova N, Antonenkova N, Odunsi K, Edwards R, Kelley J, Modugno F, Ness R, Karlan B, Walsh C, Lester J, Orsulic S, Fridley B, Vierkant R, Cunningham J, Wu X, Lu K, Liang D, Hildebrandt M, Weber R, Iversen E, Tworoger S, Poole E, Salvesen H, Krakstad C, Bjorge L, Tangen I, Pejovic T, Bean Y, Kellar M, Wentzensen N, Brinton L, Lissowska J, Garcia‐Closas M, Campbell I, Eccles D, Whittemore A, Sieh W, Rothstein J, Anton‐Culver H, Ziogas A, Phelan C, Moysich K, Goode E, Schildkraut J, Berchuck A, Pharoah P, Sellers T, Brooks‐Wilson A, Cook L, Le N. Consortium analysis of gene and gene–folate interactions in purine and pyrimidine metabolism pathways with ovarian carcinoma risk. Molecular Nutrition & Food Research 2014, 58: 2023-2035. PMID: 25066213, PMCID: PMC4197821, DOI: 10.1002/mnfr.201400068.Peer-Reviewed Original ResearchCarcinomaCase-Control StudiesDietDietary SupplementsDihydrouracil Dehydrogenase (NADP)Energy IntakeFemaleFolic AcidFolic Acid DeficiencyGenetic Predisposition to DiseaseGenome-Wide Association StudyGlobal HealthHumansMultivariate AnalysisNeoplasm ProteinsOvarian NeoplasmsPolymorphism, Single NucleotideRisk FactorsWhite People
2013
Diet and lifestyle factors and risk of subtypes of esophageal and gastric cancers: classification tree analysis
Silvera S, Mayne ST, Gammon MD, Vaughan TL, Chow WH, Dubin JA, Dubrow R, Stanford JL, West AB, Rotterdam H, Blot WJ, Risch HA. Diet and lifestyle factors and risk of subtypes of esophageal and gastric cancers: classification tree analysis. Annals Of Epidemiology 2013, 24: 50-57. PMID: 24239095, PMCID: PMC4006990, DOI: 10.1016/j.annepidem.2013.10.009.Peer-Reviewed Original ResearchMeSH KeywordsAdenocarcinomaAdultAgedAged, 80 and overCarcinoma, Squamous CellCase-Control StudiesConnecticutDietEsophageal NeoplasmsFeeding BehaviorFemaleGastroesophageal RefluxHumansIncidenceLife StyleLogistic ModelsMaleMiddle AgedNew JerseyRisk FactorsStatistics as TopicStomach NeoplasmsSurveys and QuestionnairesWashingtonYoung AdultConceptsImportant risk stratification factorRisk stratification factorsSquamous cell carcinomaRisk of subtypesGastric cardiaRisk factorsCell carcinomaGastric cancerStratification factorsPopulation-based case-control studyGastroesophageal reflux disease symptomsEsophageal squamous cell carcinomaGastroesophageal reflux diseaseCase-control studyInteraction of dietReflux diseaseLifestyle factorsWine intakeDietary factorsCancer sitesMedical factorsGastric sitesNoncitrus fruitClassification tree analysisCancer subtypesDietary Energy Density Is Positively Associated with Risk of Pancreatic Cancer in Urban Shanghai Chinese 1,2
Wang J, Zhang W, Sun L, Yu H, Ni QX, Risch HA, Gao YT. Dietary Energy Density Is Positively Associated with Risk of Pancreatic Cancer in Urban Shanghai Chinese 1,2. Journal Of Nutrition 2013, 143: 1626-1629. PMID: 23902959, PMCID: PMC3771813, DOI: 10.3945/jn.113.178129.Peer-Reviewed Original ResearchConceptsCase-control studyPancreatic cancerDietary energy densityRisk factorsPopulation-based case-control studyFood frequency questionnaire dataIndependent risk factorPancreatic cancer riskType 2 diabetesAdjusted analysisProspective studyHighest quintileLowest quintileCancer riskNormal controlsRegular consumptionCancerOverall dietRiskQuintileShanghai ChineseUrban ShanghaiQuestionnaire dataObesityDiabetesFlavonoid intake and risk of pancreatic cancer in the National Institutes of Health-AARP Diet and Health Study Cohort
Arem H, Bobe G, Sampson J, Subar AF, Park Y, Risch H, Hollenbeck A, Mayne ST, Stolzenberg-Solomon RZ. Flavonoid intake and risk of pancreatic cancer in the National Institutes of Health-AARP Diet and Health Study Cohort. British Journal Of Cancer 2013, 108: 1168-1172. PMID: 23299536, PMCID: PMC3619057, DOI: 10.1038/bjc.2012.584.Peer-Reviewed Original ResearchConceptsPancreatic cancer riskHealth-AARP DietHealth Study cohortFlavonoid intakeCancer riskHazard ratioStudy cohortTotal flavonoid intakeDietary flavonoid intakeIntake of flavonoidsProspective National InstitutesConfidence intervalsPancreatic cancer casesCox proportional hazardsNational InstitutePancreatic cancer carcinogenesisLimited epidemiological studiesSmoking statusInverse associationPancreatic cancerCancer carcinogenesisCancer casesEpidemiological studiesProportional hazardsProtective role
2012
Omega-3 and omega-6 fatty acid intakes and endometrial cancer risk in a population-based case–control study
Arem H, Neuhouser ML, Irwin ML, Cartmel B, Lu L, Risch H, Mayne ST, Yu H. Omega-3 and omega-6 fatty acid intakes and endometrial cancer risk in a population-based case–control study. European Journal Of Nutrition 2012, 52: 1251-1260. PMID: 22915050, PMCID: PMC3548981, DOI: 10.1007/s00394-012-0436-z.Peer-Reviewed Original ResearchConceptsEndometrial cancer riskFatty acid intakeCancer riskEndometrial cancerAcid intakeDietary intakePopulation-based case-control studyFish oil supplement useUnconditional logistic regression methodsLong-chain omega-3 fatty acidsOmega-3 fatty acidsIncident cancer casesCase-control studyAge-matched controlsFatty acidsPopulation-based sampleTotal fish intakeSupplement useFish intakeExtreme quartilesProtective associationCancer casesHigh intakeReduced riskFatty acids EPA
2011
Principal Component Analysis of Dietary and Lifestyle Patterns in Relation to Risk of Subtypes of Esophageal and Gastric Cancer
Silvera S, Mayne ST, Risch HA, Gammon MD, Vaughan T, Chow WH, Dubin JA, Dubrow R, Schoenberg J, Stanford JL, West AB, Rotterdam H, Blot WJ. Principal Component Analysis of Dietary and Lifestyle Patterns in Relation to Risk of Subtypes of Esophageal and Gastric Cancer. Annals Of Epidemiology 2011, 21: 543-550. PMID: 21435900, PMCID: PMC3109225, DOI: 10.1016/j.annepidem.2010.11.019.Peer-Reviewed Original ResearchMeSH KeywordsAdenocarcinomaAdultAgedBody Mass IndexCase-Control StudiesConnecticutDietEsophageal NeoplasmsFemaleGastroesophageal RefluxHealth BehaviorHumansLife StyleLogistic ModelsMaleMiddle AgedNeoplasms, Squamous CellNew JerseyPrincipal Component AnalysisRegistriesRisk FactorsStomach NeoplasmsSurveys and QuestionnairesWashingtonConceptsEsophageal squamous cell carcinomaGastric cardia adenocarcinomaRisk of EACSmoking/alcoholGastroesophageal reflux diseaseEsophageal adenocarcinomaRisk factorsGastric cancerPopulation-based case-control studyRisk of ESCCFruit/vegetable intakeLifestyle patternsSquamous cell carcinomaRisk of subtypesCase-control studyFruits/vegetablesReflux diseaseLifestyle factorsVegetable scoresCell carcinomaVegetable intakeNitrite intakeAlcohol scoresCancer casesCancer risk
2008
Food group intake and risk of subtypes of esophageal and gastric cancer
Silvera S, Mayne ST, Risch H, Gammon MD, Vaughan TL, Chow W, Dubrow R, Schoenberg JB, Stanford JL, West AB, Rotterdam H, Blot WJ, Fraumeni JF. Food group intake and risk of subtypes of esophageal and gastric cancer. International Journal Of Cancer 2008, 123: 852-860. PMID: 18537156, PMCID: PMC3008621, DOI: 10.1002/ijc.23544.Peer-Reviewed Original ResearchConceptsGastric cardia adenocarcinomaNoncardia gastric adenocarcinomaHigh-fat dairyFood group intakesCardia adenocarcinomaGastric adenocarcinomaEsophageal adenocarcinomaGroup intakesOdds ratioGastric cancerHigh intakePopulation-based case-control studyNon-cardia gastric adenocarcinomaEsophageal squamous cell carcinomaRed meatTotal meat intakeSquamous cell carcinomaTotal vegetable intakeRisk of subtypesEsophageal adenocarcinoma riskCase-control studyGastric cardiaAdenocarcinoma riskCell carcinomaRisk factors
2001
Nutrient intake and risk of subtypes of esophageal and gastric cancer.
Mayne ST, Risch HA, Dubrow R, Chow WH, Gammon MD, Vaughan TL, Farrow DC, Schoenberg JB, Stanford JL, Ahsan H, West AB, Rotterdam H, Blot WJ, Fraumeni JF. Nutrient intake and risk of subtypes of esophageal and gastric cancer. Cancer Epidemiology Biomarkers & Prevention 2001, 10: 1055-62. PMID: 11588131.Peer-Reviewed Original ResearchMeSH KeywordsAdenocarcinomaAdultAge DistributionAgedCarcinoma, Squamous CellCase-Control StudiesConfidence IntervalsConnecticutDietEsophageal NeoplasmsFemaleHumansIncidenceMaleMiddle AgedNew JerseyOdds RatioPopulation SurveillanceReference ValuesRisk AssessmentRisk FactorsSex DistributionStomach NeoplasmsWashingtonConceptsNoncardia gastric cancerGastric cancerGastric cardiaNutrient intakeEsophageal adenocarcinomaOdds ratioHigh intakeTumor typesPopulation-based case-control studyVitamin C supplement useEsophageal squamous cell carcinomaNoncardia gastric adenocarcinomaRisk of adenocarcinomaSquamous cell carcinomaRisk of subtypesCase-control studyRisk of cancerPercentile of intakeSupplement useCell carcinomaDietary nitriteGastric adenocarcinomaRisk factorsDietary cholesterolIncidence rate
1994
Dietary lactose intake, lactose intolerance, and the risk of epithelial ovarian cancer in southern Ontario (Canada)
Risch H, Jain M, Marrett L, Howe G. Dietary lactose intake, lactose intolerance, and the risk of epithelial ovarian cancer in southern Ontario (Canada). Cancer Causes & Control 1994, 5: 540-548. PMID: 7827241, DOI: 10.1007/bf01831382.Peer-Reviewed Original ResearchConceptsOral contraceptive useOvarian cancerContraceptive useLactose intoleranceTotal daily caloric intakeFull-term pregnancyEpithelial ovarian cancerCase-control studyDaily caloric intakeQuantitative diet historyDietary factorsLactose intakeCaloric intakeProtective effectDiet historyAge groupsCancerDaily consumptionIntoleranceIntakeTotal durationIntake valuesPopulation controlsRiskMore evidence
1989
Diet and Lung Cancer
Miller A, Risch H. Diet and Lung Cancer. CHEST Journal 1989, 96: 8s-9s. PMID: 2661171, DOI: 10.1378/chest.96.1_supplement.8s.Peer-Reviewed Original Research
1988
DIETARY FACTORS AND THE INCIDENCE OF CANCER OF THE URINARY BLADDER
RISCH H, BURCH J, MILLER A, HILL G, STEELE R, HOWE G. DIETARY FACTORS AND THE INCIDENCE OF CANCER OF THE URINARY BLADDER. American Journal Of Epidemiology 1988, 127: 1179-1191. PMID: 3369417, DOI: 10.1093/oxfordjournals.aje.a114911.Peer-Reviewed Original ResearchConceptsBladder cancerDietary factorsLow-calorie foodsConditional logistic regression methodsCalorie foodsIntake of cholesterolCase-control studyAge 20 yearsLife-style factorsIncidence of cancerHistory of exposureLack of associationOdds ratio estimatesArtificial sweetenersArea of residenceAverage daily intakeDiabetes mellitusCigarette smokingSubsequent riskCancer casesUrinary bladderRelevant food itemsMild increaseCancerDaily intake
1985
DIETARY FACTORS AND THE INCIDENCE OF CANCER OF THE STOMACH
RISCH H, JAIN M, CHOI N, FODOR J, PFEIFFER C, HOWE G, HARRISON L, CRAIB K, MILLER A. DIETARY FACTORS AND THE INCIDENCE OF CANCER OF THE STOMACH. American Journal Of Epidemiology 1985, 122: 947-959. PMID: 2998182, DOI: 10.1093/oxfordjournals.aje.a114199.Peer-Reviewed Original ResearchConceptsOdds ratio estimatesStomach cancerConditional logistic regression methodsVitamin C intakeCitrus fruit intakeCase-control studyIncidence of cancerArea of residenceAverage daily intakeC intakeFruit intakeRatio estimatesDietary factorsAverage daily consumptionCancer casesGastric cancerVitamin EDaily intakeCancerDietary componentsDaily consumptionLogistic regression methodIntakePopulation controlsDietary fiber