2019
Genome-wide Analysis of Common Copy Number Variation and Epithelial Ovarian Cancer Risk
Reid BM, Permuth JB, Chen YA, Fridley BL, Iversen ES, Chen Z, Jim H, Vierkant RA, Cunningham JM, Barnholtz-Sloan JS, Narod S, Risch H, Schildkraut JM, Goode EL, Monteiro AN, Sellers TA. Genome-wide Analysis of Common Copy Number Variation and Epithelial Ovarian Cancer Risk. Cancer Epidemiology Biomarkers & Prevention 2019, 28: 1117-1126. PMID: 30948450, PMCID: PMC6606353, DOI: 10.1158/1055-9965.epi-18-0833.Peer-Reviewed Original ResearchConceptsCommon CNV regionsCopy number variationsEOC susceptibilityNumber variationsTumor gene expressionGenome-wide analysisDNA copy number variationsWide association studyCommon copy number variationCancer Genome AtlasGenetic variationCNV regionsAssociation studiesFrequency variantsTCGA tumorsSomatic deletionGenome AtlasDeletion
2012
Germline Copy Number Variation and Ovarian Cancer Survival
Fridley BL, Chalise P, Tsai YY, Sun Z, Vierkant RA, Larson MC, Cunningham JM, Iversen ES, Fenstermacher D, Barnholtz-Sloan J, Asmann Y, Risch HA, Schildkraut JM, Phelan CM, Sutphen R, Sellers TA, Goode EL. Germline Copy Number Variation and Ovarian Cancer Survival. Frontiers In Genetics 2012, 3: 142. PMID: 22891074, PMCID: PMC3413872, DOI: 10.3389/fgene.2012.00142.Peer-Reviewed Original ResearchSingle nucleotide polymorphismsGenome-wide arrayCopy number variationsCopy number changesSingle-marker approachGermline copy number variationsQuality control exclusionsChromosomal regionsNumber variationsNumber variantsNucleotide polymorphismsMultiple testing correctionCNV burdenConsecutive markersComplex diseasesLarge CNVsNumber changesChromosomal gainsSmall CNVsMarker approachCNVsGermline DNACNV probesCNV classificationComplementary approaches