2001
Etiologic Mechanisms in Epithelial Ovarian Cancer
Risch H. Etiologic Mechanisms in Epithelial Ovarian Cancer. 2001, 307-319. DOI: 10.1007/978-1-4612-2092-3_30.Peer-Reviewed Original ResearchOvarian cancerEpithelial ovarian cancerOvarian neoplasmsColorectal cancerIncessant ovulationCancer deathPrimary tumorRisk factorsCommon neoplasmInvasive tumorsFrequent causeEtiologic mechanismsOlder womenEpithelial subtypesSurface epitheliumEtiologic hypothesesAdult womenCancerEtiologic heterogeneityWomenNeoplasmsTumorsDisease occurrenceGerm cellsGonadotropin
1998
Hormonal Etiology of Epithelial Ovarian Cancer, With a Hypothesis Concerning the Role of Androgens and Progesterone
Risch HA. Hormonal Etiology of Epithelial Ovarian Cancer, With a Hypothesis Concerning the Role of Androgens and Progesterone. Journal Of The National Cancer Institute 1998, 90: 1774-1786. PMID: 9839517, DOI: 10.1093/jnci/90.23.1774.Peer-Reviewed Original ResearchConceptsEpithelial ovarian cancerOvarian cancerIncessant ovulationOvarian epithelial cellsOvarian inclusion cystsEpithelial cellsRole of androgensGonadotropin hypothesisGonadotropin secretionGonadotropin stimulationHormonal etiologyColorectal cancerCancer deathInclusion cystsAndrogenic stimulationFrequent causeCancerGermline mutationsProgesterone stimulationHormonal stimulationOvulationStimulationAdditional major factorAndrogensProgesterone