2011
Possible association between a genetic polymorphism at 8q24 and risk of upper gastrointestinal cancer
Lochhead P, Ng MT, Hold GL, Rabkin CS, Vaughan TL, Gammon MD, Risch HA, Lissowska J, Mukhopadhya I, Chow WH, El-Omar EM. Possible association between a genetic polymorphism at 8q24 and risk of upper gastrointestinal cancer. European Journal Of Cancer Prevention 2011, 20: 54-57. PMID: 21102338, PMCID: PMC3020097, DOI: 10.1097/cej.0b013e328341e320.Peer-Reviewed Original ResearchConceptsOesophageal cancerOdds ratioStudy populationCancer riskPopulation-based case-control studyUpper gastrointestinal cancer riskOesophageal squamous cell carcinomaGastrointestinal cancer riskWide association studies-identified single-nucleotide polymorphismsNoncardia gastric cancerSquamous cell carcinomaUpper gastrointestinal cancerCase-control studyColorectal cancer susceptibilitySecond study populationGastric cancer casesGastric cancer riskPotential confounding variablesFirst study populationCardia cancerCell carcinomaGastrointestinal cancerInverse associationCancer casesGastric cancer
2009
CD14-159C/T and TLR9-1237T/C polymorphisms are not associated with gastric cancer risk in Caucasian populations
Hold GL, Rabkin CS, Gammon MD, Berry SH, Smith MG, Lissowska J, Risch HA, Chow WH, Mowat NA, Vaughan TL, El-Omar EM. CD14-159C/T and TLR9-1237T/C polymorphisms are not associated with gastric cancer risk in Caucasian populations. European Journal Of Cancer Prevention 2009, 18: 117-119. PMID: 19337058, PMCID: PMC2679029, DOI: 10.1097/cej.0b013e3283101292.Peer-Reviewed Original ResearchMeSH KeywordsAdenocarcinomaCase-Control StudiesEsophageal NeoplasmsFemaleGene FrequencyGenetic Predisposition to DiseaseGenetics, PopulationHumansLinkage DisequilibriumLipopolysaccharide ReceptorsMalePolandPolymorphism, Single NucleotidePromoter Regions, GeneticRisk FactorsStomach NeoplasmsToll-Like Receptor 9United StatesWhite PeopleConceptsCD14-159C/TC promoter polymorphismCase-control studyGastric cancerPromoter polymorphismGastric cancer case-control studyTLR9 -1237T/C polymorphismPopulation-based case-control studyUpper gastrointestinal tract cancerHelicobacter pylori-induced gastritisCD14-159C/T polymorphismToll-like receptor signalingCaucasian populationFrequency-matched controlsGastrointestinal tract cancerPylori-induced gastritisUpper gastrointestinal tractCancer case-control studySingle nucleotide polymorphismsHost genetic factorsPotential confounding factorsGastric cancer riskTaiwanese Chinese populationGastric carcinoma casesNoncardia gastric carcinoma