2015
Joint Effect of Genotypic and Phenotypic Features of Reproductive Factors on Endometrial Cancer Risk
Wang Z, Risch H, Lu L, Irwin ML, Mayne S, Schwartz P, Rutherford T, De Vivo I, Yu H. Joint Effect of Genotypic and Phenotypic Features of Reproductive Factors on Endometrial Cancer Risk. Scientific Reports 2015, 5: 15582. PMID: 26498156, PMCID: PMC4620445, DOI: 10.1038/srep15582.Peer-Reviewed Original ResearchConceptsEndometrial cancer riskEndometrial cancerCancer riskEstrogen exposureEndometrial cancer patientsTime of studyGenetic risk scorePotential confoundersCancer patientsMenstrual cycleReproductive factorsRisk scorePossible markerMajor causeCancerMenopauseObesityPhenotypic featuresRiskPopulation controlsAgeMenarcheWomenExposureTNMCOccupational exposure to N-nitrosamines and pesticides and risk of pancreatic cancer
Fritschi L, Benke G, Risch HA, Schulte A, Webb PM, Whiteman DC, Fawcett J, Neale RE. Occupational exposure to N-nitrosamines and pesticides and risk of pancreatic cancer. Occupational And Environmental Medicine 2015, 72: 678. PMID: 25780030, DOI: 10.1136/oemed-2014-102522.Peer-Reviewed Original ResearchConceptsCase-control studyOccupational exposurePancreatic cancerPopulation-based case-control studyLarge case-control studyLifetime job historiesPancreatic cancer developmentCigarette smokingLifestyle factorsFrequency of exposureLikelihood of exposureAnimal evidenceIncrease riskPancreatic carcinogenCancer developmentN-nitrosaminesOccupational hygienistsCancerSuch exposureJob historyRiskExposureAssociationSmokingSpecific questions
1989
Mortality from Breast Cancer after Irradiation during Fluoroscopic Examinations in Patients Being Treated for Tuberculosis
Miller A, Howe G, Sherman G, Lindsay J, Yaffe M, Dinner P, Risch H, Preston D. Mortality from Breast Cancer after Irradiation during Fluoroscopic Examinations in Patients Being Treated for Tuberculosis. New England Journal Of Medicine 1989, 321: 1285-1289. PMID: 2797101, DOI: 10.1056/nejm198911093211902.Peer-Reviewed Original ResearchConceptsBreast cancerRelative riskFluoroscopic examinationRadiation-induced breast cancerFirst exposureLinear dose-response relationUse of mammographyYears of ageDose-response relationNumber of deathsTherapeutic pneumothoraxAsymptomatic womenExcess riskLifetime riskAdditive riskCancerWomenSubstantial proportionSmall benefitAgeRadiation dosesRiskTuberculosisMortalityExposure