2011
Clinical impact of unclassified variants of the BRCA1 and BRCA2 genes
Akbari MR, Zhang S, Fan I, Royer R, Li S, Risch H, McLaughlin J, Rosen B, Sun P, Narod SA. Clinical impact of unclassified variants of the BRCA1 and BRCA2 genes. Journal Of Medical Genetics 2011, 48: 783. PMID: 21965345, DOI: 10.1136/jmedgenet-2011-100305.Peer-Reviewed Original ResearchConceptsFirst-degree relativesFemale first-degree relativesRelatives of patientsOvarian cancerCumulative riskPathogenic mutationsUnclassified variantsRisk of cancerHistorical cohortBRCA2 mutationsClinical impactHigh riskBRCA2 genesCancerUnknown significancePatientsMissense variantsFunctional effectsWomenRiskBRCA1PenetranceMutationsRelativesCohort
1986
Changes in breast self‐examination behavior in a cohort of 8214 women in the Canadian national breast screening study
Baines C, Bsc C, Risch H, Kuin J, Fan I. Changes in breast self‐examination behavior in a cohort of 8214 women in the Canadian national breast screening study. Cancer 1986, 57: 1209-1216. PMID: 3510711, DOI: 10.1002/1097-0142(19860315)57:6<1209::aid-cncr2820570625>3.0.co;2-l.Peer-Reviewed Original ResearchConceptsCanadian National Breast Screening StudyNational Breast Screening StudyBreast Screening StudyBSE frequencyBreast self-examination instructionSelf-reported BSE frequencyBSE behaviorMean numberScreening studyBreast self-examination behaviorRoutine medical examSelf-examination behaviorStudy cohortThird screenBreast examScreen 3Older womenMedical examsWomenScreen 2CohortEvaluation protocolExamCriteriaBreast