How to achieve model-robust inference in stepped wedge trials with model-based methods?
Wang B, Wang X, Li F. How to achieve model-robust inference in stepped wedge trials with model-based methods? Biometrics 2024, 80: ujae123. PMID: 39499239, PMCID: PMC11536888, DOI: 10.1093/biomtc/ujae123.Peer-Reviewed Original ResearchConceptsTreatment effect estimandsWorking correlation structureSandwich variance estimatorExchangeable working correlation structureFunction of calendar timeEffect estimandsVariance estimationLink functionStepped wedge trialEstimandsTheoretical resultsCorrelation structureWedge trialsEstimating equationsCluster randomized trialG-computationLinear mixed modelsInferencePotential outcomesMisspecificationEstimationEffective structureModel-based methodsGeneralized estimating equationsMixed modelsModel-Robust and Efficient Covariate Adjustment for Cluster-Randomized Experiments
Wang B, Park C, Small D, Li F. Model-Robust and Efficient Covariate Adjustment for Cluster-Randomized Experiments. Journal Of The American Statistical Association 2024, ahead-of-print: 1-13. DOI: 10.1080/01621459.2023.2289693.Peer-Reviewed Original ResearchCluster-randomized experimentCluster size variationNuisance functionsParametric working modelsFlexible covariate adjustmentCovariate-adjusted estimatesCovariate adjustment methodsCovariate adjustmentModel-based covariate adjustmentEfficient estimationSimulation studyRobust inferenceSupplementary materialsEstimandsEstimating equationsModel-based estimatesG-computationCluster averagesEstimationTreatment assignmentRoutine practice conditionsRisk of biasEquationsTreatment effectsCovariates