2020
Coaching Intensity, Adherence to Essential Birth Practices, and Health Outcomes in the BetterBirth Trial in Utter Pradesh, India
Barnhart DA, Spiegelman D, Zigler CM, Kara N, Delaney MM, Kalita T, Maji P, Hirschhorn LR, Semrau KEA. Coaching Intensity, Adherence to Essential Birth Practices, and Health Outcomes in the BetterBirth Trial in Utter Pradesh, India. Global Health Science And Practice 2020, 8: ghsp-d-19-00317. PMID: 32127359, PMCID: PMC7108945, DOI: 10.9745/ghsp-d-19-00317.Peer-Reviewed Original ResearchConceptsEssential birth practicesSafe Childbirth ChecklistPerinatal health outcomesBirth attendantsHealth outcomesBetterBirth trialWorld Health Organization Safe Childbirth ChecklistBirth practicesQuality of careSustain behavior changeCoaching-based interventionBehavior changeFrequent coachingPerinatal mortalityBirth facilityAdherenceOutcomesGreater improvementAttendantsVisitsTrialsMonthsRegression modelsAssociationUtter Pradesh
2005
High school dietary dairy intake and teenage acne
Adebamowo CA, Spiegelman D, Danby FW, Frazier AL, Willett WC, Holmes MD. High school dietary dairy intake and teenage acne. Journal Of The American Academy Of Dermatology 2005, 52: 207-214. PMID: 15692464, DOI: 10.1016/j.jaad.2004.08.007.Peer-Reviewed Original ResearchConceptsTeenage acnePrevalence ratiosNurses' Health Study IIDietary dairy intakeHigh school dietMultivariate prevalence ratiosHealth Study IIBody mass indexCategories of intakeLow-fat milkMass indexSchool dietDairy intakeWestern dietPresence of hormoneAcne historyPossible associationAcneEnergy intakeStudy IIIntakeBreakfast drinksConfidence intervalsTotal milkDairy foods
2004
Incidence of Laparoscopically Confirmed Endometriosis by Demographic, Anthropometric, and Lifestyle Factors
Missmer SA, Hankinson SE, Spiegelman D, Barbieri RL, Marshall LM, Hunter DJ. Incidence of Laparoscopically Confirmed Endometriosis by Demographic, Anthropometric, and Lifestyle Factors. American Journal Of Epidemiology 2004, 160: 784-796. PMID: 15466501, DOI: 10.1093/aje/kwh275.Peer-Reviewed Original ResearchMeSH KeywordsAdultAge DistributionAlcohol DrinkingAnthropometryBody ConstitutionBody Mass IndexDemographyEndometriosisFemaleFollow-Up StudiesHumansIncidenceInfertility, FemaleLaparoscopyLife StyleMiddle AgedMultivariate AnalysisNursesObesityPremenopauseProportional Hazards ModelsRisk FactorsSmokingStatistics, NonparametricUnited StatesWhite PeopleConceptsBody mass indexMass indexCigarette smokingLifestyle factorsNurses' Health Study II prospective cohortMultivariate Cox proportional hazards modelWaist/hip ratioCurrent body mass indexCox proportional hazards modelCurrent alcohol intakeCurrent cigarette smokingIncidence of endometriosisAge 18 yearsProportional hazards modelAfrican American womenPast infertilityLaparoscopic diagnosisProspective cohortAlcohol intakeHip ratioInfertility statusCaucasian womenIncidence rateCaffeine intakeHazards modelCommon ataxia telangiectasia mutated haplotypes and risk of breast cancer: a nested case–control study
Tamimi RM, Hankinson SE, Spiegelman D, Kraft P, Colditz GA, Hunter DJ. Common ataxia telangiectasia mutated haplotypes and risk of breast cancer: a nested case–control study. Breast Cancer Research 2004, 6: r416. PMID: 15217510, PMCID: PMC468661, DOI: 10.1186/bcr809.Peer-Reviewed Original ResearchMeSH KeywordsAdultAtaxia TelangiectasiaAtaxia Telangiectasia Mutated ProteinsBreast NeoplasmsCase-Control StudiesCell Cycle ProteinsCohort StudiesDNA-Binding ProteinsFemaleHaplotypesHumansMiddle AgedMutationNursesPolymorphism, Single NucleotideProtein Serine-Threonine KinasesRisk FactorsSurveys and QuestionnairesTumor Suppressor ProteinsConceptsSingle nucleotide polymorphismsATM geneDNA double-strand breaksNucleotide polymorphismsDouble-strand breaksEntire genomic sequenceTumor suppressor geneCommon variationCell cycle arrestHaplotype diversityUnique haplotypesGenomic sequencesAtaxia telangiectasiaSingle nucleotide polymorphism detectionSporadic breast cancer riskSuppressor geneCycle arrestGenesATM haplotypesPolymorphism detectionCommon haplotypeHaplotypesGenotype informationHaplotype analysisMutationsManganese Superoxide Dismutase Polymorphism, Plasma Antioxidants, Cigarette Smoking, and Risk of Breast Cancer
Tamimi RM, Hankinson SE, Spiegelman D, Colditz GA, Hunter DJ. Manganese Superoxide Dismutase Polymorphism, Plasma Antioxidants, Cigarette Smoking, and Risk of Breast Cancer. Cancer Epidemiology Biomarkers & Prevention 2004, 13: 989-996. PMID: 15184255, DOI: 10.1158/1055-9965.989.13.6.Peer-Reviewed Original ResearchConceptsBreast cancer riskHealth Study cohortBreast cancerAla alleleCancer riskCurrent smokersCigarette smokingNurses' Health Study cohortManganese superoxide dismutase polymorphismIndependent risk factorPostmenopausal hormone useCase-control studyVal/ValHormone useStudy cohortIncident casesRisk factorsPlasma antioxidantsDismutase polymorphismAlcohol consumptionVal alleleBlood collectionCancerAntioxidant levelsOxidative stress
2002
Diet quality and major chronic disease risk in men and women: moving toward improved dietary guidance 1 , 2 , 3
McCullough ML, Feskanich D, Stampfer MJ, Giovannucci EL, Rimm EB, Hu FB, Spiegelman D, Hunter DJ, Colditz GA, Willett WC. Diet quality and major chronic disease risk in men and women: moving toward improved dietary guidance 1 , 2 , 3. American Journal Of Clinical Nutrition 2002, 76: 1261-1271. PMID: 12450892, DOI: 10.1093/ajcn/76.6.1261.Peer-Reviewed Original ResearchConceptsAlternate Healthy Eating IndexRecommended Food ScoreHealthy Eating IndexChronic disease riskMajor chronic diseasesMajor chronic disease riskCardiovascular diseaseChronic diseasesDisease riskDietary guidelinesHealth StudyDiet qualityChronic disease risk reductionAgriculture Healthy Eating IndexHigher AHEI scoreNurses' Health StudyDisease risk reductionStrong inverse associationDietary questionnaireAHEI scoreLowest quintileNontraumatic deathsFood ScoreInverse associationHealth professionals
2001
Prospective Study of Zinc Intake and the Risk of Age-Related Macular Degeneration
Cho E, Stampfer M, Seddon J, Hung S, Spiegelman D, Rimm E, Willett W, Hankinson S. Prospective Study of Zinc Intake and the Risk of Age-Related Macular Degeneration. Annals Of Epidemiology 2001, 11: 328-336. PMID: 11399447, DOI: 10.1016/s1047-2797(01)00217-4.Peer-Reviewed Original ResearchConceptsAge-related macular degenerationZinc intakeRelative riskProspective studyLowest quintileMacular degenerationRisk of AMDDiagnosis of AMDSemiquantitative food frequency questionnaireMultivariate relative riskPooled relative riskFood frequency questionnaireLarge prospective studiesDietary zinc intakeVisual acuity lossTotal zinc intakePotential risk factorsRisk of AgeMultivariate adjustmentIncident casesAcuity lossHighest quintileLong-term benefitsRisk factorsZinc supplements
2000
Electric Blanket Use and Breast Cancer in the Nurses' Health Study
Laden F, Neas LM, Tolbert PE, Holmes MD, Hankinson SE, Spiegelman D, Speizer FE, Hunter DJ. Electric Blanket Use and Breast Cancer in the Nurses' Health Study. American Journal Of Epidemiology 2000, 152: 41-49. PMID: 10901328, DOI: 10.1093/aje/152.1.41.Peer-Reviewed Original ResearchConceptsElectric blanket useNurses' Health StudyBreast cancerHealth StudyBlanket useRelative riskEstrogen receptor-positive breast cancerReceptor-positive breast cancerBreast cancer risk factorsMultivariate relative riskInvasive breast cancerCancer risk factorsAge-adjusted analysesBreast cancer riskLong-term useElectric blanketBiennial questionnairesRisk factorsRetrospective analysisCancer riskProspective analysisCancerMultivariate modelSmall riskConfidence intervals
1999
Glutathione S -Transferase Mu and Theta Polymorphisms and Breast Cancer Susceptibility
García-Closas M, Kelsey K, Hankinson S, Spiegelman D, Springer K, Willett W, Speizer F, Hunter D. Glutathione S -Transferase Mu and Theta Polymorphisms and Breast Cancer Susceptibility. Journal Of The National Cancer Institute 1999, 91: 1960-1964. PMID: 10564681, DOI: 10.1093/jnci/91.22.1960.Peer-Reviewed Original ResearchConceptsGlutathione S-transferase mu 1Breast cancer riskBreast cancerGSTT1 null genotypeCancer riskOdds ratioNull genotypeGSTT1 genesConditional logistic regression modelsEndogenous mutagenic processesGlutathione S-transferase muConfidence intervalsGSTT1 gene deletionGSTT1 gene polymorphismsLogistic regression modelsHomozygous gene deletionBreast cancer susceptibilityTheta 1 genePremenopausal womenProspective cohortCigarette smokingIncident casesDecreased riskControl subjectsGSTT1 genotypeAssociation of age and reproductive factors with benign breast tissue composition.
Gertig DM, Stillman IE, Byrne C, Spiegelman D, Schnitt SJ, Connolly JL, Colditz GA, Hunter DJ. Association of age and reproductive factors with benign breast tissue composition. Cancer Epidemiology Biomarkers & Prevention 1999, 8: 873-9. PMID: 10548315.Peer-Reviewed Original ResearchConceptsStromal proportionProliferative breast diseaseBreast diseaseRisk factorsBreast tissue compositionEpithelial proportionHealth StudyReproductive breast cancer risk factorsBenign breast biopsy slidesBreast cancer risk factorsObvious mass lesionStromal breast tissueNurses' Health StudyReproductive risk factorsCancer risk factorsBenign breast biopsyBreast cancer riskCase-control studyAssociation of agePostmenopausal parous womenFibrous stromal tissueNonproliferative breast diseasePostmenopausal womenPremenopausal womenParous womenThe relationship between a polymorphism in CYP17 with plasma hormone levels and breast cancer.
Haiman CA, Hankinson SE, Spiegelman D, Colditz GA, Willett WC, Speizer FE, Kelsey KT, Hunter DJ. The relationship between a polymorphism in CYP17 with plasma hormone levels and breast cancer. Cancer Research 1999, 59: 1015-20. PMID: 10070957.Peer-Reviewed Original ResearchConceptsHealth Study cohortBreast cancer riskBreast cancerHormone levelsA2 alleleCancer riskNurses' Health Study cohortStrong independent risk factorA2/A2 genotypeCYP17 A2 alleleElevated levelsAdvanced breast cancerIncident breast cancerIndependent risk factorPolycystic ovarian syndromeCertain steroid hormonesA1/A1 genotypeCase-control studyPlasma hormone levelsSteroid hormone levelsLater agePremenopausal womenCYP17 genotypeHormone replacementOvarian syndromeN‐acetyl transferase 2 genotypes, meat intake and breast cancer risk
Gertig D, Hankinson S, Hough H, Spiegelman D, Colditz G, Willett W, Kelsey K, Hunter D. N‐acetyl transferase 2 genotypes, meat intake and breast cancer risk. International Journal Of Cancer 1999, 80: 13-17. PMID: 9935222, DOI: 10.1002/(sici)1097-0215(19990105)80:1<13::aid-ijc3>3.0.co;2-w.Peer-Reviewed Original ResearchConceptsBreast cancer riskRed meat intakeMeat intakeRapid acetylatorsBreast cancerSlow acetylatorsCancer riskHealth StudyLow red meat intakeHigh red meat intakeNurses' Health StudyHeterocyclic aminesLack of associationHigh-temperature cooking methodsFrequent intakeNAT2 genotypeBlood drawAcetylator genotypeBlood samplesAcetylatorsSignificant associationCancerIntakeMajor causeHuman carcinogenesis
1998
Risk of Uterine Leiomyomata among Premenopausal Women in Relation to Body Size and Cigarette Smoking
Marshall L, Spiegelman D, Manson J, Goldman M, Barbieri R, Stampfer M, Willett W, Hunter D. Risk of Uterine Leiomyomata among Premenopausal Women in Relation to Body Size and Cigarette Smoking. Epidemiology 1998, 9: 511-517. PMID: 9730029, DOI: 10.1097/00001648-199809000-00007.Peer-Reviewed Original ResearchConceptsBody mass indexAdult body mass indexMass indexCigarette smokingUterine leiomyomataAge 18 yearsPremenopausal womenRelative riskBody mass index categoriesMultivariate relative riskConfidence intervalsIntact uterusOvarian functionNew diagnosisLeiomyomataIndex categoriesSmokingStudy questionnaireNew casesHysterectomyAge 25Weight gainWeight changeWomenRiskA prospective study of reproductive factors and oral contraceptive use in relation to the risk of uterine leiomyomata
Marshall L, Spiegelman D, Goldman M, Manson J, Colditz G, Barbieri R, Stampfer M, Hunter D. A prospective study of reproductive factors and oral contraceptive use in relation to the risk of uterine leiomyomata. Fertility And Sterility 1998, 70: 432-439. PMID: 9757871, DOI: 10.1016/s0015-0282(98)00208-8.Peer-Reviewed Original ResearchConceptsOral contraceptive useUterine leiomyomataContraceptive useReproductive factorsOral contraceptivesProspective studySelf-reported uterine leiomyomataHistory of infertilitySelf-reported diagnosisPremenopausal nursesPremenopausal womenMedical recordsRisk factorsMAIN OUTCOMEElevated riskLast birthLeiomyomataYounger ageFirst birthNotable associationAge 13HysterectomyContraceptivesRiskAgeUse of Toenail Fluoride Levels as an Indicator for the Risk of Hip and Forearm Fractures in Women
Feskanich D, Owusu W, Hunter D, Willett W, Ascherio A, Spiegelman D, Morris S, Spate V, Colditz G. Use of Toenail Fluoride Levels as an Indicator for the Risk of Hip and Forearm Fractures in Women. Epidemiology 1998, 9: 412-416. PMID: 9647905, DOI: 10.1097/00001648-199807000-00011.Peer-Reviewed Original ResearchConceptsForearm fracturesFluoride intakeOdds ratioHealth StudyVitamin D intakeDistal forearm fracturesNurses' Health StudyRisk of hipPostmenopausal hormone useBody mass indexLong-term intakeYear of birthD intakeMenopausal statusHip fractureHormone useHighest quartileMass indexOsteoporotic fracturesSmoking statusPrevious hipHeart diseaseSubsequent riskCaffeine intakeEpidemiologic studiesCan behavioral risk factors explain the difference in body mass index between African-American and European-American women?
Holmes MD, Stampfer MJ, Wolf AM, Jones CP, Spiegelman D, Manson JE, Colditz GA. Can behavioral risk factors explain the difference in body mass index between African-American and European-American women? Ethnicity & Disease 1998, 8: 331-9. PMID: 9926903.Peer-Reviewed Original ResearchConceptsBody mass indexHigher body mass indexAfrican American womenEuropean American womenMass indexIntentional weight lossMeasurements of dietBehavioral risk factorsModifiable reasonsRisk factorsPhysical activityCalorie intakeFemale nursesAge 18Weight lossMultivariate determinantsWomenTelevision watchingMarital statusBehavioral factorsAfrican AmericansWeight differencesOccupation groupsAgeLinear regression
1997
Variation in the incidence of uterine leiomyoma among premenopausal women by age and race.
Marshall LM, Spiegelman D, Barbieri RL, Goldman MB, Manson JE, Colditz GA, Willett WC, Hunter DJ. Variation in the incidence of uterine leiomyoma among premenopausal women by age and race. Obstetrics And Gynecology 1997, 90: 967-73. PMID: 9397113, DOI: 10.1016/s0029-7844(97)00534-6.Peer-Reviewed Original ResearchConceptsUterine leiomyomaRelative riskPremenopausal womenRisk factorsIncidence rateFirst oral contraceptive useWhite womenBlack womenOral contraceptive useBody mass indexHistory of infertilityPremenopausal black womenSimilar relative riskPotential risk factorsSelf-reported diagnosisAge-standardized ratesCurrent alcohol consumptionRace-specific ratesMass indexPhysical examinationPelvic examinationMedical recordsHigh prevalenceContraceptive useLast birthGeographic Variation in Breast Cancer Incidence Rates in a Cohort of U.S. Women
Laden F, Hankinson S, Spiegelman D, Neas L, Colditz G, Hunter D, Manson J, Byrne C, Rosner B, Speizer F. Geographic Variation in Breast Cancer Incidence Rates in a Cohort of U.S. Women. Journal Of The National Cancer Institute 1997, 89: 1373-1378. PMID: 9308708, DOI: 10.1093/jnci/89.18.1373.Peer-Reviewed Original ResearchConceptsBreast cancer incidence ratesCancer incidence ratesHealth Study cohortRisk factorsIncidence ratePostmenopausal womenRelative riskHealth StudyNurses' Health Study cohortAge-adjusted breast cancer incidence ratesBreast cancer risk factorsNurses' Health StudyMultivariate-adjusted analysesAge-adjusted riskBreast cancer incidenceInvasive breast cancerBreast cancer mortalityCancer risk factorsPremenopausal womenStudy cohortIncident casesCancer mortalityExcess riskCancer incidenceBreast cancerMeasurement Error Correction for Logistic Regression Models with an “Alloyed Gold Standard”
Spiegelman D, Schneeweiss S, McDermott A. Measurement Error Correction for Logistic Regression Models with an “Alloyed Gold Standard”. American Journal Of Epidemiology 1997, 145: 184-196. PMID: 9006315, DOI: 10.1093/oxfordjournals.aje.a009089.Peer-Reviewed Original Research