2006
Alcohol intake and ovarian cancer risk: a pooled analysis of 10 cohort studies
Genkinger JM, Hunter DJ, Spiegelman D, Anderson KE, Buring JE, Freudenheim JL, Goldbohm RA, Harnack L, Hankinson SE, Larsson SC, Leitzmann M, McCullough ML, Marshall J, Miller AB, Rodriguez C, Rohan TE, Schatzkin A, Schouten LJ, Wolk A, Zhang SM, Smith-Warner SA. Alcohol intake and ovarian cancer risk: a pooled analysis of 10 cohort studies. British Journal Of Cancer 2006, 94: 757-762. PMID: 16495916, PMCID: PMC2361197, DOI: 10.1038/sj.bjc.6603020.Peer-Reviewed Original ResearchConceptsOvarian cancer riskCohort studyCancer riskPooled analysisAlcohol intakeRelative riskStudy-specific relative risksCox proportional hazards modelDepletion of folateModerate alcohol intakeOral contraceptive useProspective cohort studyHormone replacement therapyBody mass indexConfidence intervalsLevels of estrogenSerous ovarian cancerProportional hazards modelRandom-effects modelOvarian casesMenopausal statusMass indexReplacement therapyFolate intakeOvarian cancer
2005
Alcohol consumption and high-density lipoprotein levels: the effect of ADH1C genotype, gender and menopausal status
Hines LM, Hunter DJ, Stampfer MJ, Spiegelman D, Chu NF, Rifai N, Hankinson SE, Rimm EB. Alcohol consumption and high-density lipoprotein levels: the effect of ADH1C genotype, gender and menopausal status. Atherosclerosis 2005, 182: 293-300. PMID: 16051248, DOI: 10.1016/j.atherosclerosis.2005.02.005.Peer-Reviewed Original ResearchConceptsHigh-density lipoprotein levelsPostmenopausal hormonesPostmenopausal womenModerate alcohol consumptionHDL levelsOlder-aged menPremenopausal womenAlcohol consumptionADH1C genotypeLipoprotein levelsAged menCoronary heart diseaseMenopausal statusExogenous estrogenMyocardial infarctionHeart diseaseModerate drinkersOlder menFunctional polymorphismsWomenType 1CMenVaried exposureAssociationHigh levels
2000
A tetranucleotide repeat polymorphism in CYP19 and breast cancer risk
Haiman C, Hankinson S, Spiegelman D, De Vivo I, Colditz G, Willett W, Speizer F, Hunter D. A tetranucleotide repeat polymorphism in CYP19 and breast cancer risk. International Journal Of Cancer 2000, 87: 204-210. PMID: 10861475, DOI: 10.1002/1097-0215(20000715)87:2<204::aid-ijc8>3.0.co;2-3.Peer-Reviewed Original ResearchConceptsBreast cancer riskHealth Study cohortCase-control studyCancer riskHormone levelsNurses' Health Study cohortBreast cancer case-control studyElevated estrogen levelsAdvanced cancer casesCancer case-control studyRepeat polymorphismTetranucleotide repeat polymorphismConversion of androgensGreater frequencyKey steroidogenic enzymesSignificant greater frequencyDistant metastasisStudy cohortEstrogen levelsCYP19 allelesBreast cancerCancer casesAllele carriersEstrone sulfateNonsignificant increase
1998
Alcohol and Breast Cancer in Women: A Pooled Analysis of Cohort Studies
Smith-Warner SA, Spiegelman D, Yaun SS, van den Brandt PA, Folsom AR, Goldbohm RA, Graham S, Holmberg L, Howe GR, Marshall JR, Miller AB, Potter JD, Speizer FE, Willett WC, Wolk A, Hunter DJ. Alcohol and Breast Cancer in Women: A Pooled Analysis of Cohort Studies. JAMA 1998, 279: 535-540. PMID: 9480365, DOI: 10.1001/jama.279.7.535.Peer-Reviewed Original ResearchConceptsInvasive breast cancerAlcohol intakeBreast cancerAlcohol consumptionRelative riskIncident invasive breast cancerMultivariate-adjusted relative riskIncident breast cancer casesBeverage-specific alcohol consumptionMultivariate relative riskTotal alcohol intakeFood frequency questionnaireBreast cancer incidenceBreast cancer riskBreast cancer casesRandom-effects modelLong-term intakeCohort studyFrequency questionnaireProspective studyPooled analysisCancer incidenceDiet assessment instrumentsCancer casesNondietary factors