2022
Effectiveness of a community-based education and peer support led by women’s self-help groups in improving the control of hypertension in urban slums of Kerala, India: a cluster randomised controlled pragmatic trial
Suseela R, Ambika R, Mohandas S, Menon J, Numpelil M, Vasudevan B, Ved R, Danaei G, Spiegelman D. Effectiveness of a community-based education and peer support led by women’s self-help groups in improving the control of hypertension in urban slums of Kerala, India: a cluster randomised controlled pragmatic trial. BMJ Global Health 2022, 7: e010296. PMID: 36384950, PMCID: PMC9670931, DOI: 10.1136/bmjgh-2022-010296.Peer-Reviewed Original ResearchConceptsMean systolic BPSystolic BPControl armIntervention armPragmatic trialUrban slumsTarget blood pressure goalsMajor public health problemBlood pressure goalsSelf-help group membersControl of hypertensionStandard of carePublic health problemPrimary healthcare systemSelf-help groupsCommunity-based educationPeer support programAntihypertensive medicationsUncontrolled hypertensionUsual careHypertension managementPrimary outcomeHypertensionHealthy behaviorsHealth problemsStakeholder engagement in a hypertension and diabetes prevention research program: Description and lessons learned
Shrestha A, Tamrakar D, Shrestha B, Karmacharya BM, Shrestha A, Pyakurel P, Spiegelman D. Stakeholder engagement in a hypertension and diabetes prevention research program: Description and lessons learned. PLOS ONE 2022, 17: e0276478. PMID: 36264860, PMCID: PMC9584412, DOI: 10.1371/journal.pone.0276478.Peer-Reviewed Original ResearchMeSH KeywordsData CollectionDiabetes MellitusHealth Services ResearchHumansHypertensionStakeholder ParticipationConceptsStakeholder engagement
2003
Vitamin C and risk of coronary heart disease in women
Osganian SK, Stampfer MJ, Rimm E, Spiegelman D, Hu FB, Manson JE, Willett WC. Vitamin C and risk of coronary heart disease in women. Journal Of The American College Of Cardiology 2003, 42: 246-252. PMID: 12875759, DOI: 10.1016/s0735-1097(03)00575-8.Peer-Reviewed Original ResearchMeSH KeywordsAdultAge FactorsAntioxidantsAscorbic AcidChemopreventionCoronary DiseaseDiabetes ComplicationsDietary SupplementsFemaleHumansHypercholesterolemiaHypertensionIncidenceLife StyleLogistic ModelsMiddle AgedMultivariate AnalysisNutrition SurveysProportional Hazards ModelsProspective StudiesRisk FactorsSmokingSurveys and QuestionnairesUnited StatesWomen's HealthConceptsRisk of CHDCoronary heart diseaseVitamin C intakeCoronary risk factorsVitamin C supplementsC intakeVitamin CC supplementsHeart diseaseRisk factorsLower riskDetailed semiquantitative food frequency questionnaireIncidence of CHDVitamin C supplement useIncident coronary heart diseaseSemiquantitative food frequency questionnaireFood frequency questionnaireSignificant inverse associationIncident casesSupplement useProspective InvestigationInverse associationProtective associationFemale nursesTotal intakeAlcohol Consumption Patterns and HbA1c, C-Peptide and Insulin Concentrations in Men
Meyer KA, Conigrave KM, Chu NF, Rifai N, Spiegelman D, Stampfer MJ, Rimm EB. Alcohol Consumption Patterns and HbA1c, C-Peptide and Insulin Concentrations in Men. Journal Of The American Nutrition Association 2003, 22: 185-194. PMID: 12805244, DOI: 10.1080/07315724.2003.10719292.Peer-Reviewed Original ResearchConceptsC-peptideInsulin concentrationsAverage alcohol consumptionAlcohol consumptionAlcohol consumption patternsBlood samplesStudy participantsDrinking patternsDisease-free menC-peptide concentrationsModerate alcohol consumptionCross-sectional studyYears of ageFrequent alcohol consumptionFrequency of consumptionEffects of alcoholInsulin levelsBiologic markersInsulin sensitivityInverse associationAverage daily consumptionIrregular drinkersObservational studyAnalysis of insulinHealth professionals
1996
Birth weight and adult hypertension, diabetes mellitus, and obesity in US men.
Curhan G, Willett W, Rimm E, Spiegelman D, Ascherio A, Stampfer M. Birth weight and adult hypertension, diabetes mellitus, and obesity in US men. Circulation 1996, 94: 3246-50. PMID: 8989136, DOI: 10.1161/01.cir.94.12.3246.Peer-Reviewed Original ResearchConceptsAge-adjusted odds ratioAdult body mass indexLow birth weightBody mass indexDiabetes mellitusBirth weightAdult hypertensionMass indexOdds ratioChronic diseasesUS menChronic adult diseasesBirth weight categoriesDependent diabetes mellitusPrevalence of obesityRisk of hypertensionRisk of obesityHigh birth weightEarly life exposureCumulative incidenceLowest quintileMedical historyRisk factorsFamily historyLife exposureBirth weight and adult hypertension and obesity in women.
Curhan G, Chertow G, Willett W, Spiegelman D, Colditz G, Manson J, Speizer F, Stampfer M. Birth weight and adult hypertension and obesity in women. Circulation 1996, 94: 1310-5. PMID: 8822985, DOI: 10.1161/01.cir.94.6.1310.Peer-Reviewed Original ResearchConceptsAge-adjusted odds ratioHealth Study IIBody mass indexBirth weightYears of ageOdds ratioNHS IMass indexNurses' Health Study INurses' Health Study IIAdult body mass indexHealth Study INHS II cohortDevelopment of hypertensionLow birth weightPhysician-diagnosed hypertensionRisk of hypertensionHigh birth weightEarly life exposureAdult hypertensionNHS IIBlood pressureLowest quintileRisk factorsLife exposureProspective study of oral contraceptives and hypertension among women in the United States.
Chasan-Taber L, Willett W, Manson J, Spiegelman D, Hunter D, Curhan G, Colditz G, Stampfer M. Prospective study of oral contraceptives and hypertension among women in the United States. Circulation 1996, 94: 483-9. PMID: 8759093, DOI: 10.1161/01.cir.94.3.483.Peer-Reviewed Original ResearchMeSH KeywordsAdultCohort StudiesContraceptives, OralFemaleHumansHypertensionProspective StudiesRisk FactorsConceptsOral contraceptivesBody mass indexMass indexRelative riskFamily historyAge-adjusted relative riskPast usersHigh-dose pillsMultivariate relative riskOral contraceptive useProspective cohort studyRisk of hypertensionCoronary heart diseaseRisk of developmentLow-dose formulationsCurrent usersMicrograms estrogenHypertensive effectCohort studyEffect of ageBlood pressureAlcohol intakeCigarette smokingIncident casesProspective study
1992
Absolute fat mass, percent body fat, and body-fat distribution: which is the real determinant of blood pressure and serum glucose?
Spiegelman D, Israel R, Bouchard C, Willett W. Absolute fat mass, percent body fat, and body-fat distribution: which is the real determinant of blood pressure and serum glucose? American Journal Of Clinical Nutrition 1992, 55: 1033-1044. PMID: 1595574, DOI: 10.1093/ajcn/55.6.1033.Peer-Reviewed Original ResearchConceptsBody mass indexBlood pressurePercent body fatAbsolute fat massFat massSerum glucoseBody fatBlood glucoseDiastolic blood pressureBody fat distributionCigarette smoking statusCurrent cigarette smoking statusRegional fat distributionMultiple skinfold thicknessesRelative fat massMass indexFat distributionOverall body massSkinfold thicknessBody compositionStudy centersGold standardHip girthStrongest predictorUnderwater weighing