2004
Changes in whole-grain, bran, and cereal fiber consumption in relation to 8-y weight gain among men
Koh-Banerjee P, Franz M, Sampson L, Liu S, Jacobs DR, Spiegelman D, Willett W, Rimm E. Changes in whole-grain, bran, and cereal fiber consumption in relation to 8-y weight gain among men. American Journal Of Clinical Nutrition 2004, 80: 1237-1245. PMID: 15531671, DOI: 10.1093/ajcn/80.5.1237.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedDietary FiberEdible GrainHumansMaleMiddle AgedProspective StudiesUnited StatesWeight GainConceptsWhole-grain intakeLong-term weight gainWeight gainBody weightWhole grainsWhole grain consumptionDose-response relationProspective cohortLifestyle factorsD incrementMethodologic inconsistenciesFiber intakeSelf-report questionnairesEpidemiologic studiesUS menMetabolic alterationsFiber consumptionMultivariate analysisIntakeMenAssociationDietary Fiber and Risk of Coronary Heart Disease: A Pooled Analysis of Cohort Studies
Pereira MA, O'Reilly E, Augustsson K, Fraser GE, Goldbourt U, Heitmann BL, Hallmans G, Knekt P, Liu S, Pietinen P, Spiegelman D, Stevens J, Virtamo J, Willett WC, Ascherio A. Dietary Fiber and Risk of Coronary Heart Disease: A Pooled Analysis of Cohort Studies. JAMA Internal Medicine 2004, 164: 370-376. PMID: 14980987, DOI: 10.1001/archinte.164.4.370.Peer-Reviewed Original ResearchConceptsCoronary heart diseaseDietary fiber intakeHeart diseaseFiber intakeCoronary deathCoronary eventsCohort studyPooled analysisD incrementDietary fiberVegetable fiber intakeProspective cohort studyBody mass indexSex-specific resultsMass indexLifestyle factorsCoronary casesEpidemiologic studiesDiseaseIntakeDeathRiskWomenTotal dietary fiberMen
2003
Dietary Fiber Reduces Peripheral Arterial Disease Risk in Men
Merchant AT, Hu FB, Spiegelman D, Willett WC, Rimm EB, Ascherio A. Dietary Fiber Reduces Peripheral Arterial Disease Risk in Men. Journal Of Nutrition 2003, 133: 3658-3663. PMID: 14608090, DOI: 10.1093/jn/133.11.3658.Peer-Reviewed Original ResearchConceptsPeripheral arterial disease riskCereal fiber intakeArterial disease riskPAD riskFiber intakeInverse associationDisease riskEarly coronary heart diseaseIncident PAD casesFood frequency questionnaireCoronary heart diseaseTotal fiber intakeOverall inverse associationDisease QuestionnaireFrequency questionnaireLowest quintileHeart diseaseCardiovascular diseaseFamily historyPhysical activityPAD casesAlcohol consumptionEnergy intakeIntakeRiskPremenopausal dietary carbohydrate, glycemic index, glycemic load, and fiber in relation to risk of breast cancer.
Cho E, Spiegelman D, Hunter DJ, Chen WY, Colditz GA, Willett WC. Premenopausal dietary carbohydrate, glycemic index, glycemic load, and fiber in relation to risk of breast cancer. Cancer Epidemiology Biomarkers & Prevention 2003, 12: 1153-8. PMID: 14652274.Peer-Reviewed Original ResearchConceptsBody mass indexBreast cancer riskHealth Study IIGlycemic loadCarbohydrate intakeCancer riskBreast cancerGlycemic indexDietary carbohydrateRelative riskFiber intakeNurses' Health Study IIMultivariate relative riskCorresponding relative risksFood frequency questionnaireInvasive breast cancerDietary carbohydrate intakeEarly adult lifeYoung adult womenPremenopausal womenFrequency questionnaireLean womenOverall cohortOverweight womenMass indexHigh-fiber diet in HIV-positive men is associated with lower risk of developing fat deposition
Hendricks KM, Dong KR, Tang AM, Ding B, Spiegelman D, Woods MN, Wanke CA. High-fiber diet in HIV-positive men is associated with lower risk of developing fat deposition. American Journal Of Clinical Nutrition 2003, 78: 790-795. PMID: 14522738, DOI: 10.1093/ajcn/78.4.790.Peer-Reviewed Original ResearchMeSH KeywordsAdultCase-Control StudiesDietDiet RecordsDietary FiberHIV SeropositivityHumansLipodystrophyMaleRisk FactorsConceptsHIV-positive patientsFat depositionFood recordsDietary fiberHealthy Living cohortPast dietary intakeHIV-positive menCase-control studyOverall energy intakeWilcoxon rank sum testHigh-fiber dietRank sum testLiving cohortCurrent smokersDietary intakeResistance trainingLower riskEnergy intakePatientsUnhealthy behaviorsHealthy lifestyleHIVDietary componentsGreater intakeHigh-quality dietAlcohol Consumption Patterns and HbA1c, C-Peptide and Insulin Concentrations in Men
Meyer KA, Conigrave KM, Chu NF, Rifai N, Spiegelman D, Stampfer MJ, Rimm EB. Alcohol Consumption Patterns and HbA1c, C-Peptide and Insulin Concentrations in Men. Journal Of The American Nutrition Association 2003, 22: 185-194. PMID: 12805244, DOI: 10.1080/07315724.2003.10719292.Peer-Reviewed Original ResearchConceptsC-peptideInsulin concentrationsAverage alcohol consumptionAlcohol consumptionAlcohol consumption patternsBlood samplesStudy participantsDrinking patternsDisease-free menC-peptide concentrationsModerate alcohol consumptionCross-sectional studyYears of ageFrequent alcohol consumptionFrequency of consumptionEffects of alcoholInsulin levelsBiologic markersInsulin sensitivityInverse associationAverage daily consumptionIrregular drinkersObservational studyAnalysis of insulinHealth professionals
2001
Assessment of Questionnaire Validity for Measuring Total Fat Intake using Plasma Lipid Levels as Criteria
Willett W, Stampfer M, Chu NF, Spiegelman D, Holmes M, Rimm E. Assessment of Questionnaire Validity for Measuring Total Fat Intake using Plasma Lipid Levels as Criteria. American Journal Of Epidemiology 2001, 154: 1107-1112. PMID: 11744515, DOI: 10.1093/aje/154.12.1107.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overBiomarkersBody Mass IndexBody WeightCholesterol, HDLCohort StudiesCross-Sectional StudiesDiet SurveysDietary FatsDietary FiberDietary ProteinsEnergy IntakeExerciseFastingFollow-Up StudiesHumansMaleMiddle AgedProspective StudiesRegression AnalysisReproducibility of ResultsSmokingSurveys and QuestionnairesTriglyceridesConceptsTotal fat intakeFood frequency questionnaireFat intakeTriglyceride levelsFrequency questionnaireDietary fatSemiquantitative food frequency questionnaireHealth Professionals FollowBody mass indexHigh fat intakePlasma lipid levelsMetabolic studiesIntake of proteinCross-sectional analysisProfessionals FollowOverweight menMass indexInverse associationLipid levelsPhysical activityBlood specimensAlcohol consumptionSpecific biomarkersIntakeMultiple regression analysis
2000
Dietary fat intake and endogenous sex steroid hormone levels in postmenopausal women.
Holmes M, Spiegelman D, Willett W, Manson J, Hunter D, Barbieri R, Colditz G, Hankinson S. Dietary fat intake and endogenous sex steroid hormone levels in postmenopausal women. Journal Of Clinical Oncology 2000, 18: 3668-76. PMID: 11054440, DOI: 10.1200/jco.2000.18.21.3668.Peer-Reviewed Original ResearchConceptsDietary fat intakeFat intakePostmenopausal womenInverse associationHormone levelsSex steroid hormone levelsHealthy postmenopausal womenTotal fat intakeFood frequency questionnaireEndogenous estrogen levelsBreast cancer riskOmega-3 fatsSex steroid hormonesCross-sectional associationsSteroid hormone levelsPercentage of energyEstradiol levelsEstrogen levelsPlasma sex steroidsPlasma levelsSex steroidsCancer riskProtein intakeEnergy intakeSteroid hormones
1997
Dietary Fiber, Glycemic Load, and Risk of NIDDM in Men
Salmerón J, Ascherio A, Rimm E, Colditz G, Spiegelman D, Jenkins D, Stampfer M, Wing A, Willett W. Dietary Fiber, Glycemic Load, and Risk of NIDDM in Men. Diabetes Care 1997, 20: 545-550. PMID: 9096978, DOI: 10.2337/diacare.20.4.545.Peer-Reviewed Original ResearchConceptsRisk of NIDDMHigh glycemic loadGlycemic loadCereal fiberRelative riskHigher cereal fiber intakeSemiquantitative food frequency questionnaireCereal fiber intakeLarge glycemic responseDietary glycemic indexFood frequency questionnaireIncidence of NIDDMIntake of carbohydratesTotal energy intakeLow glycemic loadYears of ageDietary fiberFrequency questionnaireIncident casesLowest quintileCardiovascular diseaseFamily historyFiber intakeNIDDMPhysical activity
1996
Hormone Levels During Dietary Changes in Premenopausal African-American Women
Woods M, Barnett J, Spiegelman D, Trail N, Hertzmark E, Longcope C, Gorbach S. Hormone Levels During Dietary Changes in Premenopausal African-American Women. Journal Of The National Cancer Institute 1996, 88: 1369-1374. PMID: 8827014, DOI: 10.1093/jnci/88.19.1369.Peer-Reviewed Original ResearchConceptsSerum hormone levelsSex hormone-binding globulinAfrican American womenCaucasian womenHormone levelsControl dietFree E2Menstrual cycleSurvival ratePremenopausal African American womenClinical study unitSerum hormone valuesTwo-sided statistical testsEndogenous sex hormonesHormone-binding globulinTypical North American dietSame control dietSignificant lower levelsTypes of cancerNorth American dietHigh-fiber dietConcentrations of estroneSHBG levelsSerum estrogenAndrostenedione levelsDietary fat and risk of coronary heart disease in men: cohort follow up study in the United States
Ascherio A, Rimm E, Giovannucci E, Spiegelman D, Meir S, Willett W. Dietary fat and risk of coronary heart disease in men: cohort follow up study in the United States. The BMJ 1996, 313: 84. PMID: 8688759, PMCID: PMC2351515, DOI: 10.1136/bmj.313.7049.84.Peer-Reviewed Original ResearchConceptsCoronary heart diseaseHeart diseaseMyocardial infarctionFat intakeRisk factorsHealth professionalsFatal coronary heart diseaseNon-dietary risk factorsNon-fatal myocardial infarctionCohort questionnaire studyCoronary risk factorsMultivariate relative riskTotal fat intakeIntake of cholesterolAcute myocardial infarctionDiagnosed cardiovascular diseaseLinolenic acid intakeBlood cholesterol concentrationsIntake of fiberPositive associationCoronary deathCoronary eventsSpecific preventive effectCholesterol intakeCoronary diseaseVegetable, Fruit, and Cereal Fiber Intake and Risk of Coronary Heart Disease Among Men
Rimm EB, Ascherio A, Giovannucci E, Spiegelman D, Stampfer MJ, Willett WC. Vegetable, Fruit, and Cereal Fiber Intake and Risk of Coronary Heart Disease Among Men. JAMA 1996, 275: 447-451. PMID: 8627965, DOI: 10.1001/jama.1996.03530300031036.Peer-Reviewed Original ResearchConceptsTotal myocardial infarctionCoronary heart diseaseDietary fiber intakeMyocardial infarctionFiber intakeRelative riskCoronary diseaseHeart diseaseInverse associationCases of MIAge-adjusted relative riskTotal dietary fiber intakeDietary fiberCereal fiber intakeCardiovascular risk factorsNonfatal myocardial infarctionTotal energy intakeTotal fiber intakeCurrent national dietary guidelinesMain food contributorsFatal coronary diseaseYears of ageNational dietary guidelinesDietary questionnaireCohort study
1995
Changes in plasma lipoprotein concentrations and composition in response to a low-fat, high-fiber diet are associated with changes in serum estrogen concentrations in premenopausal women
Schaefer E, Lamon-Fava S, Spiegelman D, Dwyer J, Lichtenstein A, McNamara J, Goldin B, Woods M, Morrill-LaBrode A, Hertzmark E, Longcope C, Gorbach S. Changes in plasma lipoprotein concentrations and composition in response to a low-fat, high-fiber diet are associated with changes in serum estrogen concentrations in premenopausal women. Metabolism 1995, 44: 749-756. PMID: 7783659, DOI: 10.1016/0026-0495(95)90188-4.Peer-Reviewed Original ResearchConceptsHigh-fiber dietLuteal phasePremenopausal womenTotal cholesterolPlasma lipidsBaseline dietFollicular phaseHigh-density lipoprotein cholesterol concentrationsSerum sex hormone concentrationsLow-density lipoprotein cholesterolNormal premenopausal womenLipoprotein cholesterol concentrationsSex hormone concentrationsSerum estrogen concentrationsPlasma lipoprotein concentrationsSerum estrone sulphate concentrationsEstrone sulfate concentrationsLow-density lipoproteinLipoprotein cholesterolLipoprotein levelsSerum hormonesLipoprotein concentrationsMenstrual cyclePlasma triglyceridesTG concentrations
1994
The effect of dietary fat and fiber on serum estrogen concentrations in premenopausal women under controlled dietary conditions
Goldin B, Woods M, Spiegelman D, Longcope C, Morrill‐LaBrode A, Dwyer J, Gualtieri L, Hertzmark E, Gorbach S. The effect of dietary fat and fiber on serum estrogen concentrations in premenopausal women under controlled dietary conditions. Cancer 1994, 74: 1125-1131. PMID: 8039147, DOI: 10.1002/1097-0142(19940801)74:3+<1125::aid-cncr2820741521>3.0.co;2-5.Peer-Reviewed Original ResearchConceptsPremenopausal womenSerum concentrationsSex hormonesDietary fatEstrone sulfateSerum sex hormonesSerum estrogen concentrationsSignificant decreaseInitial control periodDietary fiberMetabolic kitchenFollicular phaseMenstrual cycleFree estradiolAmount of fatEstrogen concentrationsHigh fiberDietary conditionsControl periodEstradiolIndependent effectsWomenAndrostenedioneFatHormone
1992
Dietary fat and fiber in relation to risk of breast cancer. An 8-year follow-up.
Willett WC, Hunter DJ, Stampfer MJ, Colditz G, Manson JE, Spiegelman D, Rosner B, Hennekens CH, Speizer FE. Dietary fat and fiber in relation to risk of breast cancer. An 8-year follow-up. JAMA 1992, 268: 2037-44. PMID: 1328696, DOI: 10.1001/jama.268.15.2037.Peer-Reviewed Original ResearchConceptsTotal fat intakeBreast cancer incidenceFat intakeBreast cancerPostmenopausal womenCancer incidenceProtective effectHealth StudySelf-administered food frequency questionnaireEnergy intakePositive associationDietary fat increasesNurses' Health StudyProspective cohort studyFood frequency questionnaireTotal energy intakeMiddle-aged womenYears of ageDietary questionnaireCohort studyFrequency questionnaireIncident casesRisk factorsDietary fatCorresponding RRs