2023
Mediation analysis in the presence of continuous exposure measurement error
Cheng C, Spiegelman D, Li F. Mediation analysis in the presence of continuous exposure measurement error. Statistics In Medicine 2023, 42: 1669-1686. PMID: 36869626, PMCID: PMC11320713, DOI: 10.1002/sim.9693.Peer-Reviewed Original ResearchConceptsBody mass indexExposure measurement errorPhysical activityMediation proportionHealth Professionals FollowCardiovascular disease incidenceProfessionals FollowMediation analysisMass indexCardiovascular diseaseLower riskStudy designEffect estimatesValidation study designContinuous exposureBiased effect estimatesTrue exposureMediatorsExposureValidation studyBinary outcomesHealth science studiesOutcomesRiskDisease incidence
2021
A Bayesian approach for estimating the partial potential impact fraction with exposure measurement error under a main study/internal validation design
Chen X, Chang J, Spiegelman D, Li F. A Bayesian approach for estimating the partial potential impact fraction with exposure measurement error under a main study/internal validation design. Statistical Methods In Medical Research 2021, 31: 404-418. PMID: 34841964, DOI: 10.1177/09622802211060514.Peer-Reviewed Original ResearchConceptsPotential impact fractionImpact fractionExposure measurement errorHealth professionalsStudy designColorectal cancer incidenceValidation study designBurden of diseaseRisk factorsCancer incidenceHealth StudyDisease casesPublic health studiesRed meatContinuous exposureExposureProfessionalsIncidenceReclassification approachValidation designDiseaseIntakeswdpwr: A SAS macro and an R package for power calculations in stepped wedge cluster randomized trials
Chen J, Zhou X, Li F, Spiegelman D. swdpwr: A SAS macro and an R package for power calculations in stepped wedge cluster randomized trials. Computer Methods And Programs In Biomedicine 2021, 213: 106522. PMID: 34818620, PMCID: PMC8665077, DOI: 10.1016/j.cmpb.2021.106522.Peer-Reviewed Original ResearchConceptsWedge clusterIntracluster correlation coefficientContinuous outcomesCross-sectional cohortBinary outcomesExchangeable correlation structureWedge designPublic health intervention evaluationsHealth services researchClosed cohort designPower calculationCohort designClosed cohortStudy designIntracluster correlationIntervention evaluationNeeds of investigatorsOutcomesTrialsCohortServices researchInvestigatorsPrevious studiesSWD
2020
Estimation and inference for the population attributable risk in the presence of misclassification
Wong BHW, Lee J, Spiegelman D, Wang M. Estimation and inference for the population attributable risk in the presence of misclassification. Biostatistics 2020, 22: 805-818. PMID: 32112073, PMCID: PMC8966954, DOI: 10.1093/biostatistics/kxz067.Peer-Reviewed Original ResearchConceptsPopulation attributable riskAttributable riskPartial population attributable riskHigh red meat intakeColorectal cancer incidenceRed meat intakeAlcohol intakeRisk factorsCancer incidenceMeat intakeEpidemiologic studiesPublic health researchDisease casesStudy designValidation study designInternal validation studyHealth researchTarget populationIntakeValidation studyRiskHealth evaluation methodPresence of misclassificationIncidenceDisease
2005
A comparison of regression calibration approaches for designs with internal validation data
Thurston S, Williams P, Hauser R, Hu H, Hernandez-Avila M, Spiegelman D. A comparison of regression calibration approaches for designs with internal validation data. Journal Of Statistical Planning And Inference 2005, 131: 175-190. DOI: 10.1016/j.jspi.2003.12.015.Peer-Reviewed Original Research
2004
Breastfeeding and maternal HIV-1 disease progression and mortality
Sedgh G, Spiegelman D, Larsen U, Msamanga G, Fawzi WW. Breastfeeding and maternal HIV-1 disease progression and mortality. AIDS 2004, 18: 1043-1049. PMID: 15096808, DOI: 10.1097/00002030-200404300-00013.Peer-Reviewed Original ResearchConceptsHIV-1 disease progressionCD4 cell countDisease progressionCell countHigher CD4 cell countsLow CD4 cell countsCox proportional hazards modelHealth of HIVCohort study designExcessive weight lossProportional hazards modelPartial breastfeedingRelative riskHazards modelInsufficient evidenceBreastfeedingMultivariate analysisStudy designWeight lossWomenProgressionDar es SalaamHIVDeathAssociation
2002
Changes in lean body mass and total body weight are weakly associated with physical functioning in patients with HIV infection
Wilson I, Jacobson D, Roubenoff R, Spiegelman D, Knox T, Gorbach S. Changes in lean body mass and total body weight are weakly associated with physical functioning in patients with HIV infection. HIV Medicine 2002, 3: 263-270. PMID: 12444944, DOI: 10.1046/j.1468-1293.2002.00122.x.Peer-Reviewed Original ResearchConceptsTotal body weightSelf-reported physical functioningPhysical functioningHIV infectionBody weightRelationship of changesCells/ micro l.Mean CD4 countHIV-positive personsMain outcome measuresLean body massLongitudinal analysisCD4 countCohort studyPositive personsOutcome measuresHealthy personsBody compositionPatientsStudy designWeight lossMicro l.InfectionWomenHealthy living
1991
Cost-efficient study designs for binary response data with Gaussian covariate measurement error.
Spiegelman D, Gray R. Cost-efficient study designs for binary response data with Gaussian covariate measurement error. Biometrics 1991, 47: 851-69. PMID: 1789885, DOI: 10.2307/2532644.Peer-Reviewed Original ResearchConceptsStudy designValidation studyEpidemiologic cohort studiesOverall sample sizeExposure measurementsCohort studyOutcome ascertainmentRelative riskExposure measurement methodsSample of subjectsExposure variablesOptimal study designDisease frequencySample sizeInternal validation studyExposure assessmentValidation substudySubjectsPrimary investigationBest methodProportionSubstudyStudy