2018
Phthalate Metabolites and Postmenopausal Breast Cancer Risk
Reeves K, Diaz S, Hankinson, Bigelow C, Zoeller, Manson J, Spiegelman D, Tinker L. Phthalate Metabolites and Postmenopausal Breast Cancer Risk. Cancer Epidemiology Biomarkers & Prevention 2018, 27: 355-355. DOI: 10.1158/1055-9965.epi-18-0052.Peer-Reviewed Original ResearchBreast cancer riskPhthalate metabolitesCancer riskWomen’s Health Initiative prospective cohortMultivariable conditional logistic regression analysisConditional logistic regression analysisHuman breast cancer riskIndividual phthalate metabolitesBody mass indexMono-2-ethylhexyl phthalateAnimal model evidenceCase-control studyHuman breast milkLogistic regression analysisRace/ethnicityProspective cohortSmoking statusEnrollment dateMass indexBreast milkProspective dataRisk ratioStudy groupMonoethyl phthalateResults Overall
2003
Occupational exposure to methyl tertiary butyl ether in relation to key health symptom prevalence: the effect of measurement error correction
Keshaviah A, Weller E, Spiegelman D. Occupational exposure to methyl tertiary butyl ether in relation to key health symptom prevalence: the effect of measurement error correction. Environmetrics 2003, 14: 573-582. DOI: 10.1002/env.604.Peer-Reviewed Original ResearchEffect of MTBEHealth symptomsStudy participantsJob categoriesSmoking statusSerum concentrationsBlood concentrationsHealth outcomesMTBE exposureEye irritationSignificant associationSymptomsMethyl tertiary butyl etherAvailable dataPrevalenceExposureExposure effectsParticipantsLow levelsHeadacheRegression calibration methodIrritationDietary carotenoids and risk of coronary artery disease in women 1 , 2 , 3
Osganian SK, Stampfer MJ, Rimm E, Spiegelman D, Manson JE, Willett WC. Dietary carotenoids and risk of coronary artery disease in women 1 , 2 , 3. American Journal Of Clinical Nutrition 2003, 77: 1390-1399. PMID: 12791615, DOI: 10.1093/ajcn/77.6.1390.Peer-Reviewed Original ResearchConceptsRisk of CADCoronary artery diseaseArtery diseaseHigh intakePrevention of CADIncident coronary artery diseaseSemiquantitative food frequency questionnaireCAD risk factorsBeta-carotene supplementationFood frequency questionnaireCurrent smoking statusDietary carotenoidsSignificant inverse associationLutein/zeaxanthinHigh blood concentrationsConsumption of carotenoidsCAD riskSmoking statusIncident casesHighest quintileLowest quintileInverse associationRisk factorsDietary intakeBlood concentrations
2002
Mercury and the Risk of Coronary Heart Disease in Men
Yoshizawa K, Rimm EB, Morris JS, Spate VL, Hsieh CC, Spiegelman D, Stampfer MJ, Willett WC. Mercury and the Risk of Coronary Heart Disease in Men. New England Journal Of Medicine 2002, 347: 1755-1760. PMID: 12456851, DOI: 10.1056/nejmoa021437.Peer-Reviewed Original ResearchConceptsCoronary heart diseaseHeart diseaseMale health professionalsHigh dietary intakeYears of ageCase-control designMercury levelsSmoking statusTotal mercury exposureControl subjectsLowest quintileRisk factorsDietary intakeCardiovascular diseaseRelative riskCohort membersPrevious historyToenail clippingsHealth professionalsDiseaseConsumption of fishMercury exposureMean mercury levelRiskFish consumption
2001
Association between dietary patterns and plasma biomarkers of obesity and cardiovascular disease risk 1 , 2 , 3
Fung T, Rimm E, Spiegelman D, Rifai N, Tofler G, Willett W, Hu F. Association between dietary patterns and plasma biomarkers of obesity and cardiovascular disease risk 1 , 2 , 3. American Journal Of Clinical Nutrition 2001, 73: 61-67. PMID: 11124751, DOI: 10.1093/ajcn/73.1.61.Peer-Reviewed Original ResearchConceptsMajor dietary patternsFood frequency questionnaireBiomarkers of obesityDietary patternsHomocysteine concentrationsHigh intakePattern scoresHigh-fat dairy productsHealth Professionals FollowOverall dietary patternsCardiovascular disease riskBody mass indexPlasma folate concentrationsPrudent patternProfessionals FollowCVD riskDevelopment of diseaseSmoking statusAlcohol intakeMass indexPotential confoundersObesity riskPlasma biomarkersPlasma folateRisk factors
1999
Fruit and Vegetable Intake and Incidence of Bladder Cancer in a Male Prospective Cohort
Michaud D, Spiegelman D, Clinton S, Rimm E, Willett W, Giovannucci E. Fruit and Vegetable Intake and Incidence of Bladder Cancer in a Male Prospective Cohort. Journal Of The National Cancer Institute 1999, 91: 605-613. PMID: 10203279, DOI: 10.1093/jnci/91.7.605.Peer-Reviewed Original ResearchConceptsBladder cancer riskVegetable intakeCancer riskBladder cancerCruciferous vegetablesIndividual cruciferous vegetablesHealth Professionals FollowTotal fruitProspective cohort studyCruciferous vegetable consumptionFood frequency questionnaireCurrent smoking statusIncident bladder cancerPrevious epidemiologic studiesTotal fluid intakeLogistic regression analysisCarotenoid-rich vegetablesProfessionals FollowCohort studyProspective cohortSmoking statusCigarette smokingGreen leafy vegetablesInverse associationFluid intake
1998
Study of Prediagnostic Selenium Level in Toenails and the Risk of Advanced Prostate Cancer
Yoshizawa K, Willett W, Morris S, Stampfer M, Spiegelman D, Rimm E, Giovannucci E. Study of Prediagnostic Selenium Level in Toenails and the Risk of Advanced Prostate Cancer. Journal Of The National Cancer Institute 1998, 90: 1219-1224. PMID: 9719083, DOI: 10.1093/jnci/90.16.1219.Peer-Reviewed Original ResearchConceptsAdvanced prostate cancerProstate cancerProspective studyControl subjectsHealth professionalsSelenium levelsMale health professionalsFurther prospective studiesBody mass indexLong-term selenium intakeSelenium intakeCase-control designHigh selenium intakeLycopene intakeCalcium intakeMass indexPrediagnostic levelsRandomized trialsSmoking statusFat intakeIntervention trialsFamily historyCohort membersDaily supplementToenail clippingsUse of Toenail Fluoride Levels as an Indicator for the Risk of Hip and Forearm Fractures in Women
Feskanich D, Owusu W, Hunter D, Willett W, Ascherio A, Spiegelman D, Morris S, Spate V, Colditz G. Use of Toenail Fluoride Levels as an Indicator for the Risk of Hip and Forearm Fractures in Women. Epidemiology 1998, 9: 412-416. PMID: 9647905, DOI: 10.1097/00001648-199807000-00011.Peer-Reviewed Original ResearchConceptsForearm fracturesFluoride intakeOdds ratioHealth StudyVitamin D intakeDistal forearm fracturesNurses' Health StudyRisk of hipPostmenopausal hormone useBody mass indexLong-term intakeYear of birthD intakeMenopausal statusHip fractureHormone useHighest quartileMass indexOsteoporotic fracturesSmoking statusPrevious hipHeart diseaseSubsequent riskCaffeine intakeEpidemiologic studies
1997
Calcium Intake and the Incidence of Forearm and Hip Fractures among Men 1 , 2
Owusu W, Willett W, Feskanich D, Ascherio A, Spiegelman D, Colditz G. Calcium Intake and the Incidence of Forearm and Hip Fractures among Men 1 , 2. Journal Of Nutrition 1997, 127: 1782-1787. PMID: 9278560, DOI: 10.1093/jn/127.9.1782.Peer-Reviewed Original ResearchConceptsIncidence of forearmCalcium intakeBody mass indexHip fractureRelative riskForearm fracturesComparable relative riskHealth Professionals FollowHigh calcium intakeTotal energy intakeRisk of fractureGlass of milkMen 40Professionals FollowModerate traumaMass indexSmoking statusLifestyle factorsHighest quintileLowest quintileEpidemiologic studiesPhysical activityLower riskAlcohol consumptionEnergy intake