2021
Impact of the Affordable Care Act on Colorectal Cancer Incidence and Mortality
Lee C, Kushi LH, Reed ME, Eldridge EH, Lee JK, Zhang J, Spiegelman D. Impact of the Affordable Care Act on Colorectal Cancer Incidence and Mortality. American Journal Of Preventive Medicine 2021, 62: 387-394. PMID: 34763959, PMCID: PMC8863627, DOI: 10.1016/j.amepre.2021.08.025.Peer-Reviewed Original ResearchConceptsColorectal cancer-related mortalityColorectal cancer incidenceCancer-related mortalityColorectal cancer outcomesAffordable Care ActCancer incidenceColorectal cancerCancer outcomesCare ActKaiser Permanente Northern California membersHealth plansColorectal cancer screeningInterrupted time series designRace/ethnicityCancer screeningCalifornia membersPreventive servicesPrivate health insurancePocket costsMortalityTime series designIncidenceCost sharingCancerComparison group
2018
Phthalate Metabolites and Postmenopausal Breast Cancer Risk
Reeves K, Diaz S, Hankinson, Bigelow C, Zoeller, Manson J, Spiegelman D, Tinker L. Phthalate Metabolites and Postmenopausal Breast Cancer Risk. Cancer Epidemiology Biomarkers & Prevention 2018, 27: 355-355. DOI: 10.1158/1055-9965.epi-18-0052.Peer-Reviewed Original ResearchBreast cancer riskPhthalate metabolitesCancer riskWomen’s Health Initiative prospective cohortMultivariable conditional logistic regression analysisConditional logistic regression analysisHuman breast cancer riskIndividual phthalate metabolitesBody mass indexMono-2-ethylhexyl phthalateAnimal model evidenceCase-control studyHuman breast milkLogistic regression analysisRace/ethnicityProspective cohortSmoking statusEnrollment dateMass indexBreast milkProspective dataRisk ratioStudy groupMonoethyl phthalateResults Overall
2005
Temporal Relationship Between Elevation of Epstein-Barr Virus Antibody Titers and Initial Onset of Neurological Symptoms in Multiple Sclerosis
Levin LI, Munger KL, Rubertone MV, Peck CA, Lennette ET, Spiegelman D, Ascherio A. Temporal Relationship Between Elevation of Epstein-Barr Virus Antibody Titers and Initial Onset of Neurological Symptoms in Multiple Sclerosis. JAMA 2005, 293: 2496-2500. PMID: 15914750, DOI: 10.1001/jama.293.20.2496.Peer-Reviewed Original ResearchConceptsViral capsid antigenEpstein-Barr virusMultiple sclerosisAntibody titersEBNA complexRelative riskDevelopment of MSEBV viral capsid antigenEpstein-Barr virus (EBV) antibody titersRisk of MSOnset of MSOnset of symptomsVirus antibody titersSerum antibody titersCase-control studyDefense Serum RepositoryAge 25 yearsBlood sample collectionUS military personnelTemporal relationshipCase-control setsRace/ethnicityAge-dependent relationshipEBV infectionCytomegalovirus antibodies
2003
Multiple Sclerosis and Epstein-Barr Virus
Levin LI, Munger KL, Rubertone MV, Peck CA, Lennette ET, Spiegelman D, Ascherio A. Multiple Sclerosis and Epstein-Barr Virus. JAMA 2003, 289: 1533-1536. PMID: 12672770, DOI: 10.1001/jama.289.12.1533.Peer-Reviewed Original ResearchConceptsViral capsid antigenEpstein-Barr virusRisk of MSMultiple sclerosisRelative riskDevelopment of MSEBV viral capsid antigenOnset of MSCase-control studyDefense Serum RepositoryBlood sample collectionUS military personnelRace/ethnicityEBNA complexEBV antibodiesEBV infectionCytomegalovirus antibodiesSerum levelsCapsid antigenEarly antigenMS onsetAntibody titersIgG antibodiesPermanent disabilitySerum Repository
2001
House Dust Endotoxin and Wheeze in the First Year of Life
PARK J, GOLD D, SPIEGELMAN D, BURGE H, MILTON D. House Dust Endotoxin and Wheeze in the First Year of Life. American Journal Of Respiratory And Critical Care Medicine 2001, 163: 322-328. PMID: 11179100, DOI: 10.1164/ajrccm.163.2.2002088.Peer-Reviewed Original ResearchConceptsElevated endotoxinEndotoxin exposureMultivariate modelLower respiratory illnessMultivariate relative riskHistory of asthmaLow birth weightSignificant univariate associationsFirst yearHouse dust endotoxinRoom dustRace/ethnicityMaternal asthmaPrimary outcomeRespiratory illnessAbove covariatesBirth weightDust endotoxinRelative riskCockroach allergensUnivariate associationsFamilial predispositionBedroom floorWheezeBirth cohort