2008
Relations of dietary type of protein, glutamine, and glutamate to the incidence of type 2 diabetes mellitus among middle‐aged women
Lenders C, HU F, Willett W, Douglas W, Sampson L, Dougherty L, Spiegelman D, Liu S. Relations of dietary type of protein, glutamine, and glutamate to the incidence of type 2 diabetes mellitus among middle‐aged women. The FASEB Journal 2008, 22: 299.5-299.5. DOI: 10.1096/fasebj.22.1_supplement.299.5.Peer-Reviewed Original ResearchMiddle-aged womenCereal fiberType 2 diabetes mellitusTotal proteinMultivariate modelModest inverse relationFood frequency questionnaireIncidence of diabetesMajor chronic diseasesProportional hazards modelFrequency questionnaireDiabetes mellitusIncident casesChronic diseasesT2DMDietary habitsHazards modelLifestyle variablesNew casesDietary typesIncidenceWomenInverse relationStudy findingsGlutamine
2000
Glycemic status and soluble tumor necrosis factor receptor levels in relation to plasma leptin concentrations among normal weight and overweight US men
Chu N, Spiegelman D, Rifai N, Hotamisligil G, Rimm E. Glycemic status and soluble tumor necrosis factor receptor levels in relation to plasma leptin concentrations among normal weight and overweight US men. International Journal Of Obesity 2000, 24: 1085-1092. PMID: 11033975, DOI: 10.1038/sj.ijo.0801361.Peer-Reviewed Original ResearchConceptsPlasma leptinSTNF-R1C-peptideOverweight menGlycemic statusLeptin concentrationsGlucose homeostasisSoluble tumor necrosis factor receptor levelsSoluble tumour necrosis factor receptor concentrationsTumor necrosis factor receptor levelsDetailed lifestyle questionnaireSTNF-R2 concentrationsHealth Professionals FollowBody mass indexPlasma leptin levelsObesity-related disordersAdipose-derived cytokineCross-sectional studyConsiderable inter-individual variationProfessionals FollowDiabetes mellitusLeptin levelsMass indexNormal weightHighest quintile
1997
A Prospective Study of Pregravid Determinants of Gestational Diabetes Mellitus
Solomon CG, Willett WC, Carey VJ, Rich-Edwards J, Hunter DJ, Colditz GA, Stampfer MJ, Speizer FE, Spiegelman D, Manson JE. A Prospective Study of Pregravid Determinants of Gestational Diabetes Mellitus. JAMA 1997, 278: 1078-1083. PMID: 9315766, DOI: 10.1001/jama.1997.03550130052036.Peer-Reviewed Original ResearchConceptsGestational diabetes mellitusBody mass indexPregravid body mass indexHealth Study IIDiabetes mellitusGDM riskWeight gainMaternal ageRisk factorsRelative riskFamily historyRisk of GDMNurses' Health Study IIPrevious gestational diabetes mellitusHigher body mass indexNoninsulin-dependent diabetes mellitusGDM risk factorsProspective cohort studyMedical record reviewEarly adulthoodPossible preventive strategiesIdentification of womenSubstantial weight gainAdvanced maternal ageGreater weight gain
1996
Birth weight and adult hypertension, diabetes mellitus, and obesity in US men.
Curhan G, Willett W, Rimm E, Spiegelman D, Ascherio A, Stampfer M. Birth weight and adult hypertension, diabetes mellitus, and obesity in US men. Circulation 1996, 94: 3246-50. PMID: 8989136, DOI: 10.1161/01.cir.94.12.3246.Peer-Reviewed Original ResearchConceptsAge-adjusted odds ratioAdult body mass indexLow birth weightBody mass indexDiabetes mellitusBirth weightAdult hypertensionMass indexOdds ratioChronic diseasesUS menChronic adult diseasesBirth weight categoriesDependent diabetes mellitusPrevalence of obesityRisk of hypertensionRisk of obesityHigh birth weightEarly life exposureCumulative incidenceLowest quintileMedical historyRisk factorsFamily historyLife exposure