2004
Early life menstrual characteristics and pregnancy experiences among women with and without major depression: the Harvard study of moods and cycles
Harlow BL, Cohen LS, Otto MW, Spiegelman D, Cramer DW. Early life menstrual characteristics and pregnancy experiences among women with and without major depression: the Harvard study of moods and cycles. Journal Of Affective Disorders 2004, 79: 167-176. PMID: 15023491, DOI: 10.1016/s0165-0327(02)00459-7.Peer-Reviewed Original ResearchConceptsRisk of depressionMajor depressionHeavy menstrual flowMenstrual cycle characteristicsMonths of breastfeedingNumber of livebirthsYears of menstruationCurrent major depressionHistory of depressionMost risk estimatesPopulation-based sampleYears of ageWomen 36Menstrual characteristicsGynecological careStudy enrollmentDecreased riskMenstrual flowMenstrual cyclePostpartum periodCycle irregularityPsychiatric sequelaePregnancy experiencePremenstrual dysphoriaMultiple abortions
1999
Glutathione S -Transferase Mu and Theta Polymorphisms and Breast Cancer Susceptibility
García-Closas M, Kelsey K, Hankinson S, Spiegelman D, Springer K, Willett W, Speizer F, Hunter D. Glutathione S -Transferase Mu and Theta Polymorphisms and Breast Cancer Susceptibility. Journal Of The National Cancer Institute 1999, 91: 1960-1964. PMID: 10564681, DOI: 10.1093/jnci/91.22.1960.Peer-Reviewed Original ResearchConceptsGlutathione S-transferase mu 1Breast cancer riskBreast cancerGSTT1 null genotypeCancer riskOdds ratioNull genotypeGSTT1 genesConditional logistic regression modelsEndogenous mutagenic processesGlutathione S-transferase muConfidence intervalsGSTT1 gene deletionGSTT1 gene polymorphismsLogistic regression modelsHomozygous gene deletionBreast cancer susceptibilityTheta 1 genePremenopausal womenProspective cohortCigarette smokingIncident casesDecreased riskControl subjectsGSTT1 genotypeRecreational Physical Activity and the Risk of Cholecystectomy in Women
Leitzmann M, Rimm E, Willett W, Spiegelman D, Grodstein F, Stampfer M, Colditz G, Giovannucci E. Recreational Physical Activity and the Risk of Cholecystectomy in Women. New England Journal Of Medicine 1999, 341: 777-784. PMID: 10477775, DOI: 10.1056/nejm199909093411101.Peer-Reviewed Original ResearchConceptsRisk of cholecystectomyRecreational physical activityMultivariate relative riskPhysical activityGallstone diseaseRelative riskSedentary behaviorHealth StudyBody weightCases of cholecystectomyRecent weight lossNurses' Health StudyYears of ageSymptomatic cholelithiasisDecreased riskLowest quintileRisk factorsCholecystectomyWeight lossWeight changeWomenDiseaseActivity levelsWeeksRiskA Prospective Study of Coffee Consumption and the Risk of Symptomatic Gallstone Disease in Men
Leitzmann MF, Willett WC, Rimm EB, Stampfer MJ, Spiegelman D, Colditz GA, Giovannucci E. A Prospective Study of Coffee Consumption and the Risk of Symptomatic Gallstone Disease in Men. JAMA 1999, 281: 2106-2112. PMID: 10367821, DOI: 10.1001/jama.281.22.2106.Peer-Reviewed Original ResearchConceptsSymptomatic gallstone diseaseGallstone diseaseRelative riskCoffee consumptionDecreased riskRisk factorsCaffeine intakeHealth professionalsUS male health professionalsMale health professionalsRegular coffeeProspective cohort studyFood frequency questionnaireConsumption of coffeeCohort studyFrequency questionnaireProspective studyMore cupsMetabolic effectsUS menGallstone formationDecaffeinated coffeeDiseaseMenCholecystectomyFluid Intake and the Risk of Bladder Cancer in Men
Michaud D, Spiegelman D, Clinton S, Rimm E, Curhan G, Willett W, Giovannucci E. Fluid Intake and the Risk of Bladder Cancer in Men. New England Journal Of Medicine 1999, 340: 1390-1397. PMID: 10228189, DOI: 10.1056/nejm199905063401803.Peer-Reviewed Original ResearchConceptsTotal fluid intakeTotal daily fluid intakeDaily fluid intakeBladder cancerFluid intakeMultivariate relative riskFood frequency questionnaireFrequency of voidingHigh fluid intakeLogistic regression analysisProspective Health ProfessionalsFrequency of urinationFrequency of consumptionDecreased riskHighest quintileType of beverageLowest quintileRisk factorsRelative riskLower riskUrinary metabolitesHealth professionalsCancerIntakeRiskProspective Study of Alcohol Consumption Patterns in Relation to Symptomatic Gallstone Disease in Men
Leitzmann M, Giovannucci E, Stampfer M, Spiegelman D, Colditz G, Willett W, Rimm E. Prospective Study of Alcohol Consumption Patterns in Relation to Symptomatic Gallstone Disease in Men. Alcohol Clinical And Experimental Research 1999, 23: 835-841. PMID: 10371403, DOI: 10.1111/j.1530-0277.1999.tb04191.x.Peer-Reviewed Original ResearchConceptsSymptomatic gallstone diseaseGallstone diseaseAlcohol intakeAlcohol consumption patternsDecreased riskAmount of alcoholAlcohol consumptionCohort of menAlcoholic beverage typesSymptomatic gallstonesFrequent intakeModerate intakeProspective studyRisk factorsSignificant associationDiseaseIntakeBeverage typePotential health hazardsRiskMenAlcoholic beveragesHealth hazardsAssociationConsumption patterns
1997
Comparison of dietary calcium with supplemental calcium and other nutrients as factors affecting the risk for kidney stones in women.
Curhan GC, Willett WC, Speizer FE, Spiegelman D, Stampfer MJ. Comparison of dietary calcium with supplemental calcium and other nutrients as factors affecting the risk for kidney stones in women. Annals Of Internal Medicine 1997, 126: 497-504. PMID: 9092314, DOI: 10.7326/0003-4819-126-7-199704010-00001.Peer-Reviewed Original ResearchConceptsHealth Study ISymptomatic kidney stonesDietary calciumSupplemental calciumRelative riskKidney stonesCalcium intakeHighest quintileLowest quintileRisk factorsSelf-administered food frequency questionnaireIncident symptomatic kidney stonesNurses' Health Study IStone formationAbsorption of oxalateFollowing relative risksDietary calcium intakeProspective cohort studyFood frequency questionnaireMain outcome measuresPotential risk factorsYears of ageCohort studyDecreased riskCalcium ingestion