Infant Nasopharyngeal Microbiota Subphenotypes and Early Childhood Lung Function: Evidence from a Rural Ghanaian Pregnancy Cohort
Dubowski K, Kaali S, Jack D, Prah RKD, Clemente JC, Tawiah T, Mujtaba M, Iddrisu L, Carrión D, Konadu DG, Agyei O, Kornu FM, Osei-Owusu S, Lee AG, Asante KP. Infant Nasopharyngeal Microbiota Subphenotypes and Early Childhood Lung Function: Evidence from a Rural Ghanaian Pregnancy Cohort. International Journal Of Environmental Research And Public Health 2021, 18: 7276. PMID: 34299726, PMCID: PMC8305530, DOI: 10.3390/ijerph18147276.Peer-Reviewed Original ResearchConceptsLung functionNasopharyngeal microbiotaPregnancy cohortLung healthPolymerase chain reactionRespiratory microbiotaLatent class analysisMassTag polymerase chain reactionGhana Randomized Air PollutionFuture lung healthChildhood lung functionSmall airway resistanceMultivariable linear regression modelsProspective pregnancy cohortAge four yearsAsymptomatic childrenMiddle-income countriesPulmonary diseaseAirway resistanceImpulse oscillometryNasopharyngeal swabsSubphenotypesCohortMore pathogensChain reaction