2022
Microbe Profile: Wigglesworthia glossinidia: the tsetse fly’s significant other
Weiss BL, Rio RVM, Aksoy S. Microbe Profile: Wigglesworthia glossinidia: the tsetse fly’s significant other. Microbiology 2022, 168: 001242. PMID: 36129743, PMCID: PMC10723186, DOI: 10.1099/mic.0.001242.Peer-Reviewed Original ResearchConceptsPhysiological homeostasisNutritional roleEssential nutritional roleUnique physiological adaptationsTsetse fliesFly microbiotaWigglesworthia glossinidiaObligate mutualistsHost fitnessAncient associationParasitic trypanosomesLarval periodPhysiological adaptationsFitness outcomesTsetse's abilityAntimicrobial responsesImmune systemAmidasesFliesMicrobiotaMutualistsWigglesworthiaEndosymbiontsGenomeB vitamins
2021
Infection with endosymbiotic Spiroplasma disrupts tsetse (Glossina fuscipes fuscipes) metabolic and reproductive homeostasis
Son JH, Weiss BL, Schneider DI, Dera KM, Gstöttenmayer F, Opiro R, Echodu R, Saarman NP, Attardo GM, Onyango M, Abdalla A, Aksoy S. Infection with endosymbiotic Spiroplasma disrupts tsetse (Glossina fuscipes fuscipes) metabolic and reproductive homeostasis. PLOS Pathogens 2021, 17: e1009539. PMID: 34529715, PMCID: PMC8478229, DOI: 10.1371/journal.ppat.1009539.Peer-Reviewed Original ResearchConceptsReproductive fitnessSpiroplasma infectionSex-biased gene expressionHigh-throughput RNA sequencingReproductive physiologyIntrauterine larval developmentMale reproductive fitnessPathogenic African trypanosomesEndosymbiotic bacteriaFly resistanceTsetse fecundityFemale spermathecaFemale fecundityRNA sequencingLarval developmentSpiroplasmaGene expressionAfrican trypanosomesReproductive tissuesReproductive homeostasisTsetse hostHuman diseasesPopulation sizeProtective phenotypeLab lines
2012
Enhancing tsetse fly refractoriness to trypanosome infection – A new IAEA coordinated research project
Van Den Abbeele J, Bourtzis K, Weiss B, Cordón-Rosales C, Miller W, Abd-alla AM, Parker A. Enhancing tsetse fly refractoriness to trypanosome infection – A new IAEA coordinated research project. Journal Of Invertebrate Pathology 2012, 112: s142-s147. PMID: 22841950, DOI: 10.1016/j.jip.2012.07.020.Peer-Reviewed Original Research
2008
Paratransgenesis Applied for Control of Tsetse Transmitted Sleeping Sickness
Aksoy S, Weiss B, Attardo G. Paratransgenesis Applied for Control of Tsetse Transmitted Sleeping Sickness. Advances In Experimental Medicine And Biology 2008, 627: 35-48. PMID: 18510012, DOI: 10.1007/978-0-387-78225-6_3.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsGene Expression RegulationSymbiosisTransgenesTrypanosomiasis, AfricanTsetse FliesConceptsGenetic transformation systemForeign gene productsSodalis symbiontsSymbiotic microbesNew vector control strategiesTsetse symbiontsFunctional biologyTransmission biologyGene productsHost functionsSymbiontsTsetse vectorDisease cycleControl of trypanosomiasisTrypanosome transmissionImmunity effectorsTransformation systemTransformation technologyBiologyGenomicsCurrent knowledgeVector control strategiesAnimal healthTrypanocidal compoundsSleeping Sickness