2012
An environmental epigenetic study of ADRB2 5′‐UTR methylation and childhood asthma severity
Fu A, Leaderer BP, Gent JF, Leaderer D, Zhu Y. An environmental epigenetic study of ADRB2 5′‐UTR methylation and childhood asthma severity. Clinical & Experimental Allergy 2012, 42: 1575-1581. PMID: 22862293, PMCID: PMC3673701, DOI: 10.1111/j.1365-2222.2012.04055.x.Peer-Reviewed Original ResearchConceptsChildhood asthma severityAsthma severitySevere asthmaSignificant associationSevere childhood asthmaBeta-agonist treatmentBeta-2 adrenergic receptorsImportant environmental exposuresAsthma exacerbationsAsthma medicationsMild asthmaChildhood asthmaSurrogate biomarkerMethylation-specific PCRPotential joint effectsClinical relevanceAdrenergic receptorsAsthmaADRB2SeverityEnvironmental exposuresIndoor exposureChildrenAssociationBlood
2003
Cigarette smoking and risk of non-Hodgkin lymphoma subtypes among women
Morton L, Holford T, Leaderer B, Boyle P, Zahm S, Zhang Y, Flynn S, Tallini G, Zhang B, Owens P, Zheng T. Cigarette smoking and risk of non-Hodgkin lymphoma subtypes among women. British Journal Of Cancer 2003, 89: 2087-2092. PMID: 14647142, PMCID: PMC2376853, DOI: 10.1038/sj.bjc.6601388.Peer-Reviewed Original ResearchConceptsNon-Hodgkin lymphomaCumulative lifetime exposureCurrent smoking statusCigarette smokingNHL subtypesFollicular lymphomaLifetime exposurePopulation-based case-control studyRisk of NHLEtiology of NHLNon-Hodgkin lymphoma subtypesDuration of smokingIntensity of smokingPrevious epidemiologic studiesCase-control studyPopulation-based controlsHistologic typeSmoking statusIncident casesTumor gradeLymphoma subtypesEpidemiologic studiesSmokingImmunologic typeLymphoma
1996
Maternal Caffeine Consumption and Spontaneous Abortion: A Prospective Cohort Study
Dlugosz L, Belanger K, Hellenbrand K, Holford T, Leaderer B, Bracken M. Maternal Caffeine Consumption and Spontaneous Abortion: A Prospective Cohort Study. Epidemiology 1996, 7: 250-255. PMID: 8728437, DOI: 10.1097/00001648-199605000-00008.Peer-Reviewed Original ResearchConceptsSpontaneous abortionCaffeine consumptionYale-New Haven HospitalMaternal caffeine consumptionProspective cohort studyCohort studyEarly pregnancyPregnant womenOdds ratioSoda drinkingElevated riskCaffeine beveragesBeverage consumptionCaffeine beverage consumptionCigarette useFirst monthPregnancySixteenth weekObserved associationsAbortionCup of teaCaffeineTeaGestationHospital