Trial of retinol and isotretinoin in skin cancer prevention: a randomized, double-blind, controlled trial. Southwest Skin Cancer Prevention Study Group.
Levine N, Moon T, Cartmel B, Bangert J, Rodney S, Dong Q, Peng Y, Alberts D. Trial of retinol and isotretinoin in skin cancer prevention: a randomized, double-blind, controlled trial. Southwest Skin Cancer Prevention Study Group. Cancer Epidemiology Biomarkers & Prevention 1997, 6: 957-61. PMID: 9367070.Peer-Reviewed Original ResearchConceptsCutaneous squamous cell carcinomaSquamous cell carcinomaBasal cell carcinomaNonmelanoma skin cancerCell carcinomaSkin cancerPlacebo-controlled trialHigh-risk subjectsSkin cancer preventionEffect of retinolOral retinolStudy clinicCancer preventionOutcome measuresIsotretinoinBeneficial effectsStudy periodRetinolTrialsCarcinomaCancerPreventionTotal numberParticipantsPlaceboRetinoids in prevention of skin cancer
Moon T, Levine N, Cartmel B, Bangert J. Retinoids in prevention of skin cancer. Cancer Letters 1997, 114: 203-205. PMID: 9103292, DOI: 10.1016/s0304-3835(97)04663-6.Peer-Reviewed Original ResearchConceptsBasal cell skin cancerModerate-risk subjectsPrior skin cancersHigh-risk subjectsRisk subjectsSkin cancerB trialSquamous cell skin cancerSquamous cell cancerEffects of retinoidsActinic keratosesCell cancerClinical trialsIntervention durationCancerTrialsRetinolRetinoidsPlaceboIncidencePreventionSubjectsSignificant benefitsIsotretinoinKeratoses