2024
Impact of a community health worker led intervention for improved blood pressure control in urban Nepal: an open-label cluster randomised controlled trial
Bhattarai S, Skovlund E, Shrestha A, Mjølstad B, Åsvold B, Sen A. Impact of a community health worker led intervention for improved blood pressure control in urban Nepal: an open-label cluster randomised controlled trial. The Lancet Regional Health - Southeast Asia 2024, 29: 100461. PMID: 39220804, PMCID: PMC11364134, DOI: 10.1016/j.lansea.2024.100461.Peer-Reviewed Original ResearchCommunity health workersIntervention arm compared to controlsWaist-to-hip ratioHealth workersRandomised controlled trialsBody mass indexPhysical activityDaily salt intakeHealthcare providersSystolic blood pressureDiastolic blood pressureCluster randomised controlled trialOpen-label cluster randomised controlled trialRoutine follow-up careMass indexHealth system barriersAdequate physical activityControlled trialsTrained healthcare providersDiet quality scoresBlood pressure controlPublic health facilitiesInterventions targeting individualsUrban NepalControl blood pressure
2023
Effectiveness of a group-based Diabetes Prevention Education Program (DiPEP) in a population with pre-diabetes: a cluster randomised controlled trial in Nepal
Shakya P, Shrestha A, Bajracharya M, Shrestha A, Kulseng B, Karmacharya B, Shrestha S, Das S, Shrestha I, Barun K, Shrestha N, Skovlund E, Sen A. Effectiveness of a group-based Diabetes Prevention Education Program (DiPEP) in a population with pre-diabetes: a cluster randomised controlled trial in Nepal. BMJ Nutrition Prevention & Health 2023, 6: 253-263. PMID: 38264365, PMCID: PMC10800278, DOI: 10.1136/bmjnph-2023-000702.Peer-Reviewed Original ResearchDiabetes prevention education programControl armIntervention armEducational sessionsMean differencePrevention education programPostintervention assessmentsLifestyle intervention programLifestyle intervention studyTRIAL REGISTRATION NUMBERTwo-arm clusterSecondary outcomesDiabetes preventionMiddle-income countriesPrimary outcomeTreat analysisWaist circumferenceMonths interventionPhysical activityRegistration numberGrain intakeIntervention studiesBaseline measuresSignificant weight reductionIntervention programs
2021
Diabetes Prevention Education Program in a population with pre-diabetes in Nepal: a study protocol of a cluster randomised controlled trial (DiPEP)
Shakya P, Shrestha A, Karmacharya BM, Shrestha A, Kulseng BE, Skovlund E, Sen A. Diabetes Prevention Education Program in a population with pre-diabetes in Nepal: a study protocol of a cluster randomised controlled trial (DiPEP). BMJ Open 2021, 11: e047067. PMID: 34819277, PMCID: PMC8614149, DOI: 10.1136/bmjopen-2020-047067.Peer-Reviewed Original ResearchConceptsDiabetes prevention education programIntervention armPrevention education programControl armRandom blood sugar valuesIndian Diabetes Risk ScoreNepal Health Research CouncilLifestyle intervention programDiabetes Risk ScoreBlood sugar valuesInstitutional Review CommitteeHealth Research CouncilKathmandu University SchoolWorkers/volunteersHealth Research EthicsDiabetes burdenStudy protocolHealthcare workersTwo-armHigh-income countriesOutcome measuresPhysical activityRisk scoreHealth literacyQualitative study
2017
Determining the Prevalence of and Risk Factors for Depressive Symptoms among Adults in Nepal.
Lam MS, Fitzpatrick AL, Shrestha A, Karmacharya BM, Koju R, Rao D. Determining the Prevalence of and Risk Factors for Depressive Symptoms among Adults in Nepal. International Journal Of Noncommunicable Diseases 2017, 2: 18-26. PMID: 30574570, PMCID: PMC6298440, DOI: 10.4103/jncd.jncd_34_16.Peer-Reviewed Original ResearchNon-communicable diseasesDhulikhel Heart StudyBody mass indexRisk factorsDepressive symptomsChi-squared testAdults age 18 yearsCardiovascular risk factorsEpidemiologic Studies Depression ScalePrevalence of depressionSignificant risk factorsLongitudinal cohort studyBaseline questionnaire dataMultiple logistic regressionAge 18 yearsPearson's chi-squared testMajor depressive symptomatologyCross-sectional analysisCESD scoresCohort studyMass indexHypertensive statusPhysical inactivityDepression ScalePhysical activity
2016
Food patterns measured by principal component analysis and obesity in the Nepalese adult
Shrestha A, Koju RP, Beresford SA, Chan K, Karmacharya BM, Fitzpatrick AL. Food patterns measured by principal component analysis and obesity in the Nepalese adult. Heart Asia 2016, 8: 46. PMID: 27326232, PMCID: PMC4898623, DOI: 10.1136/heartasia-2015-010666.Peer-Reviewed Original ResearchBody mass indexRisk factorsDietary patternsNepalese adultsHigh prevalenceFood patternsTraditional cardiovascular risk factorsDhulikhel Heart StudyFast food patternCardiovascular risk factorsMajor dietary patternsFood frequency questionnaireSystolic blood pressureTraditional risk factorsMultivariate logistic regressionFast food intakeCross-sectional studyFrequency questionnaireBlood pressureMass indexAlcohol intakeObesity prevalenceFood intakePhysical activityHeart Study