2021
Implementation of a pooled surveillance testing program for asymptomatic SARS-CoV-2 infections in K-12 schools and universities
Mendoza RP, Bi C, Cheng HT, Gabutan E, Pagapas G, Khan N, Hoxie H, Hanna S, Holmes K, Gao N, Lewis R, Wang H, Neumann D, Chan A, Takizawa M, Lowe J, Chen X, Kelly B, Asif A, Barnes K, Khan N, May B, Chowdhury T, Pollonini G, Gouda N, Guy C, Gordon C, Ayoluwa N, Colon E, Miller-Medzon N, Jones S, Hossain R, Dodson A, Weng M, McGaskey M, Vasileva A, Lincoln AE, Sikka R, Wyllie AL, Berke EM, Libien J, Pincus M, Premsrirut PK. Implementation of a pooled surveillance testing program for asymptomatic SARS-CoV-2 infections in K-12 schools and universities. EClinicalMedicine 2021, 38: 101028. PMID: 34308321, PMCID: PMC8286123, DOI: 10.1016/j.eclinm.2021.101028.Peer-Reviewed Original ResearchSARS-CoV-2School transmissionAsymptomatic SARS-CoV-2 infectionRoutine COVID-19 testingSARS-CoV-2 infectionOverall viral burdenCOVID-19 testingViral burdenNasopharyngeal swabsSaliva specimensPrevention protocolsPCR testingKappa agreementWeekly testingCost-effective strategyPooled testingSaliva analysisMolecular assaysSurveillance methodsSafety protocolsDescriptive statisticsSchool closuresTestingStrong evidenceInfection
2017
Sequencing of the variable region of rpsB to discriminate between Streptococcus pneumoniae and other streptococcal species
Wyllie AL, Pannekoek Y, Bovenkerk S, van Engelsdorp Gastelaars J, Ferwerda B, van de Beek D, Sanders EAM, Trzciński K, van der Ende A. Sequencing of the variable region of rpsB to discriminate between Streptococcus pneumoniae and other streptococcal species. Open Biology 2017, 7: 170074. PMID: 28931649, PMCID: PMC5627049, DOI: 10.1098/rsob.170074.Peer-Reviewed Original ResearchConceptsSevere streptococcal diseaseUpper respiratory tractHuman upper respiratory tractSerotype-specific assaysMolecular assaysStreptococcal speciesNon-typeable pneumococciStreptococcal diseaseAsymptomatic individualsFalse-positive resultsRespiratory tractPneumococcal isolatesCarriage isolatesStreptococcal isolatesStreptococcus pneumoniaeLack of specificityStreptococciPositive resultsPneumococciDiseaseCarriageAssaysIsolatesVast majorityMeningitis