2023
Effectiveness of a group-based Diabetes Prevention Education Program (DiPEP) in a population with pre-diabetes: a cluster randomised controlled trial in Nepal
Shakya P, Shrestha A, Bajracharya M, Shrestha A, Kulseng B, Karmacharya B, Shrestha S, Das S, Shrestha I, Barun K, Shrestha N, Skovlund E, Sen A. Effectiveness of a group-based Diabetes Prevention Education Program (DiPEP) in a population with pre-diabetes: a cluster randomised controlled trial in Nepal. BMJ Nutrition Prevention & Health 2023, 6: 253-263. PMID: 38264365, PMCID: PMC10800278, DOI: 10.1136/bmjnph-2023-000702.Peer-Reviewed Original ResearchDiabetes prevention education programControl armIntervention armEducational sessionsMean differencePrevention education programPostintervention assessmentsLifestyle intervention programLifestyle intervention studyTRIAL REGISTRATION NUMBERTwo-arm clusterSecondary outcomesDiabetes preventionMiddle-income countriesPrimary outcomeTreat analysisWaist circumferenceMonths interventionPhysical activityRegistration numberGrain intakeIntervention studiesBaseline measuresSignificant weight reductionIntervention programs
2021
Socioeconomic Status and Its Relation to Hypertension in Rural Nepal
Bhattarai S, Tandstad B, Shrestha A, Karmacharya B, Sen A. Socioeconomic Status and Its Relation to Hypertension in Rural Nepal. International Journal Of Hypertension 2021, 2021: 5542438. PMID: 34497724, PMCID: PMC8419497, DOI: 10.1155/2021/5542438.Peer-Reviewed Original ResearchLifestyle factorsBlood pressureMiddle-income countriesPrevalence ratiosSocioeconomic positionBlood pressure-lowering medicinesAge-standardized prevalenceSocioeconomic statusDiastolic blood pressureSystolic blood pressureRural health centersCross-sectional studySocioeconomic factorsRural NepalPoisson regression modelsHypertension prevalenceHypertensive participantsHealth centersHypertensionStudy participantsCausal mediation analysisConfidence intervalsSelf-reported dataEvidence of mediationFurther studies
2020
Cardiovascular disease trends in Nepal – An analysis of global burden of disease data 2017
Bhattarai S, Aryal A, Pyakurel M, Bajracharya S, Baral P, Citrin D, Cox H, Dhimal M, Fitzpatrick A, Jha AK, Jha N, Karmacharya BM, Koju R, Maharjan R, Oli N, Pyakurel P, Sapkota BP, Shrestha R, Shrestha S, Spiegelman D, Vaidya A, Shrestha A. Cardiovascular disease trends in Nepal – An analysis of global burden of disease data 2017. IJC Heart & Vasculature 2020, 30: 100602. PMID: 32775605, PMCID: PMC7399110, DOI: 10.1016/j.ijcha.2020.100602.Peer-Reviewed Original ResearchBurden of CVDCardiovascular diseaseGlobal burdenBlood pressureTotal DALYsRisk factorsDiet lowTotal deathsHigh low-density lipoprotein cholesterolHigher systolic blood pressureLow-density lipoprotein cholesterolMajor public health problemCardiovascular disease trendsPredominant cardiovascular diseasesCardiovascular disease incidenceDensity lipoprotein cholesterolSystolic blood pressureHigh blood pressureIschemic heart diseaseBody mass indexEvaluation's Global BurdenPublic health problemOlder age groupsLipoprotein cholesterolMiddle-income countriesAn integrated intervention for chronic care management in rural Nepal: protocol of a type 2 hybrid effectiveness-implementation study
Schwarz D, Dhungana S, Kumar A, Acharya B, Agrawal P, Aryal A, Baum A, Choudhury N, Citrin D, Dangal B, Dhimal M, Gauchan B, Gupta T, Halliday S, Karmacharya B, Kishore S, Koirala B, Kshatriya U, Levine E, Maru S, Rimal P, Sapkota S, Schwarz R, Shrestha A, Thapa A, Maru D. An integrated intervention for chronic care management in rural Nepal: protocol of a type 2 hybrid effectiveness-implementation study. Trials 2020, 21: 119. PMID: 31996250, PMCID: PMC6990567, DOI: 10.1186/s13063-020-4063-3.Peer-Reviewed Original ResearchMeSH KeywordsAlcohol DrinkingAllied Health PersonnelChronic DiseaseCommunity Health WorkersDecision Support Systems, ClinicalDisease ManagementHumansImplementation ScienceMedication AdherenceMotivational InterviewingNepalNoncommunicable DiseasesRisk Reduction BehaviorRural PopulationTobacco Use CessationConceptsHybrid effectiveness-implementation studyEffectiveness-implementation studyChronic care managementMid-level practitionersCare management interventionCommunity health workersCare managementMiddle-income countriesHealth workersChronic care management programWorld Health Organization PackageRisk factor optimizationClinical decision support toolEvidence-based careCare management programPrimary care systemRural NepalTobacco consumption levelsEvidence-based componentsMultiple comorbiditiesSecondary outcomesUniversal health coveragePrimary outcomeMedication adherencePre-post designEstimated cost for cardiovascular disease risk-based management at a primary healthcare center in Nepal
Aryal A, Citrin D, Halliday S, Kumar A, Nepal P, Shrestha A, Nugent R, Schwarz D. Estimated cost for cardiovascular disease risk-based management at a primary healthcare center in Nepal. Global Health Research And Policy 2020, 5: 2. PMID: 32016159, PMCID: PMC6988194, DOI: 10.1186/s41256-020-0130-2.Peer-Reviewed Original ResearchConceptsPrimary healthcare centersNon-communicable diseasesHealthcare centersCardiovascular diseasePrimary preventionCatchment populationPrimary CVD preventionBurden of disabilityDirect medical costsAnnual incremental costCost of screeningMiddle-income country settingsGlobal Hearts InitiativeIncremental work loadEligible patientsCVD preventionMiddle-income countriesTreatment protocolHearts InitiativeMedical costsOne-year time horizonAmount of medicineHealthcare providersLaboratory testsPhysician workload
2019
Designing and implementing an integrated non-communicable disease primary care intervention in rural Nepal
Kumar A, Schwarz D, Acharya B, Agrawal P, Aryal A, Choudhury N, Citrin D, Dangal B, Deukmedjian G, Dhimal M, Dhungana S, Gauchan B, Gupta T, Halliday S, Jha D, Kalaunee S, Karmacharya B, Kishore S, Koirala B, Kunwar L, Mahar R, Maru S, Mehanni S, Nirola I, Pandey S, Pant B, Pathak M, Poudel S, Rajbhandari I, Raut A, Rimal P, Schwarz R, Shrestha A, Thapa A, Thapa P, Thapa R, Wong L, Maru D. Designing and implementing an integrated non-communicable disease primary care intervention in rural Nepal. BMJ Global Health 2019, 4: e001343. PMID: 31139453, PMCID: PMC6509610, DOI: 10.1136/bmjgh-2018-001343.Peer-Reviewed Original ResearchChronic obstructive pulmonary diseaseObstructive pulmonary diseaseNon-communicable disease interventionsPulmonary diseaseMiddle-income countriesDisease interventionFacility visitsNon-communicable disease careFurther implementation researchCommunity visitsPrimary care interventionsNon-communicable diseasesRural NepalType II diabetesMedian timeDisease careCare coordinationCare interventionsII diabetesHypertensionDiabetesDiseaseVisitsRetrospective assessmentImplementation research