2016
Comparison of Smoking History Patterns Among African American and White Cohorts in the United States Born 1890 to 1990.
Holford TR, Levy DT, Meza R. Comparison of Smoking History Patterns Among African American and White Cohorts in the United States Born 1890 to 1990. Nicotine & Tobacco Research 2016, 18 Suppl 1: s16-29. PMID: 26980861, PMCID: PMC5009449, DOI: 10.1093/ntr/ntv274.Peer-Reviewed Original ResearchConceptsNational Health Interview SurveySmoking-related diseasesSmoking historyHealth Interview SurveySurgeon General's ReportBirth cohortCessation probabilitiesSmoking intensityAfrican AmericansUS National Health Interview SurveyInterview SurveyNumber of cigarettesHigh smoking prevalenceLower cessation ratesCurrent smoking behaviorLife course exposuresAdverse health effectsLower cessationSmoking exposureCessation ratesSmoking prevalenceHigh prevalenceGeneral's ReportSmoking behaviorYounger age
1997
The increase of Hodgkin's disease incidence among young adults
Chen Y, Zheng T, Chou M, Boyle P, Holford T. The increase of Hodgkin's disease incidence among young adults. Cancer 1997, 79: 2209-2218. PMID: 9179069, DOI: 10.1002/(sici)1097-0142(19970601)79:11<2209::aid-cncr20>3.0.co;2-z.Peer-Reviewed Original ResearchConceptsHodgkin's disease incidenceHodgkin's diseaseRisk factorsVirus infectionYoung adultsEpstein-Barr virus infectionHuman immunodeficiency virus (HIV) infectionConnecticut Tumor RegistryImmunodeficiency virus infectionAnalytical epidemiologic studiesMajor risk factorIncidence rate changesAdults ages 20Young adults ages 20Tumor RegistryHistologic typeDisease incidenceCohort analysisEpidemiologic studiesAge 20Cohort patternsCohort phenomenonIncidenceDiseaseYoung females
1996
Sex Differences in Survival After Myocardial Infarction in Older Adults: A Community‐Based Approach
Vaccarino V, Krumholz H, de Leon C, Holford T, Seeman T, Horwitz R, Berkman L. Sex Differences in Survival After Myocardial Infarction in Older Adults: A Community‐Based Approach. Journal Of The American Geriatrics Society 1996, 44: 1174-1182. PMID: 8855995, DOI: 10.1111/j.1532-5415.1996.tb01366.x.Peer-Reviewed Original ResearchConceptsMyocardial infarctionMultivariable adjustmentClinical severityRelative riskPsychosocial factorsOlder individualsProspective cohort studyMain outcome measuresDemographic factorsSex differencesHospital complicationsCause mortalityLate mortalityClinical characteristicsCohort studyCT cohortHospital admissionOverall mortalityEarly mortalityElderly ProgramMean agePhysical functionFunctional statusMedical recordsOutcome measuresMalignant melanoma risk factors by anatomic site: A case‐control study and polychotomous logistic regression analysis
Chen Y, Dubrow R, Holford T, Zheng T, Barnhill R, Fine J, Berwick M. Malignant melanoma risk factors by anatomic site: A case‐control study and polychotomous logistic regression analysis. International Journal Of Cancer 1996, 67: 636-643. PMID: 8782651, DOI: 10.1002/(sici)1097-0215(19960904)67:5<636::aid-ijc8>3.0.co;2-v.Peer-Reviewed Original ResearchConceptsMelanoma risk factorsCase-control studyRisk factorsAnatomic sitesSun exposurePopulation-based case-control studySun exposure-related factorsIntermittent sun exposureHistory of sunburnOnly risk factorPolychotomous logistic regression analysisInvasive melanoma casesNumber of neviLogistic regression analysisExposure-related factorsDevelopment of melanomaSex differencesPolychotomous logistic regressionHistologic subtypeMalignant melanomaClothing habitsPigmentary characteristicsMelanoma casesStudy subjectsLogistic regression
1994
Time trend and the age‐period‐cohort effect on the incidence of histologic types of lung cancer in connecticut, 1960‐1989
Zheng T, Holford T, Boyle P, Chen Y, Ward B, Flannery J, Mayne S. Time trend and the age‐period‐cohort effect on the incidence of histologic types of lung cancer in connecticut, 1960‐1989. Cancer 1994, 74: 1556-1567. PMID: 8062189, DOI: 10.1002/1097-0142(19940901)74:5<1556::aid-cncr2820740511>3.0.co;2-0.Peer-Reviewed Original ResearchMeSH KeywordsAdenocarcinomaAdenocarcinoma, Bronchiolo-AlveolarAdultAge FactorsAgedAged, 80 and overCarcinomaCarcinoma, Small CellCarcinoma, Squamous CellCohort EffectCohort StudiesConnecticutFemaleHumansIncidenceLung NeoplasmsMaleMiddle AgedModels, StatisticalRegistriesSex FactorsSmokingTime FactorsConceptsAge-adjusted incidence ratesMajor histologic typesOverall age-adjusted incidence rateAge-specific incidence ratesHistologic typeLung cancer incidenceLung cancerIncidence rateBirth cohortRecent birth cohortsIncidence patternsObserved time trendsCell carcinomaCancer incidenceTime trendsConnecticut Tumor RegistryIncidence of adenocarcinomaSmall cell carcinomaSquamous cell carcinomaLung cancer casesRecent epidemiologic studiesDifferent histologic typesDifferent incidence patternsObserved incidence patternsTumor RegistryAge‐period‐cohort modelling of large‐bowel‐cancer incidence by anatomic sub‐site and sex in Denmark
Dubrow R, Johansen C, Skov T, Holford T. Age‐period‐cohort modelling of large‐bowel‐cancer incidence by anatomic sub‐site and sex in Denmark. International Journal Of Cancer 1994, 58: 324-329. PMID: 8050812, DOI: 10.1002/ijc.2910580303.Peer-Reviewed Original ResearchMalignant melanoma incidence in Connecticut (United States): time trends and age-period-cohort modeling by anatomic site
Chen Y, Zheng T, Holford T, Berwick M, Dubrow R. Malignant melanoma incidence in Connecticut (United States): time trends and age-period-cohort modeling by anatomic site. Cancer Causes & Control 1994, 5: 341-350. PMID: 8080946, DOI: 10.1007/bf01804985.Peer-Reviewed Original ResearchConceptsCutaneous malignant melanomaAnatomic sitesUpper limbPopulation-based Connecticut Tumor RegistryCohort patternsConnecticut Tumor RegistryMale-female ratioMalignant melanoma incidenceTime trendsCMM incidenceNeck melanomaTumor RegistryIncident casesMalignant melanomaMelanoma incidenceEtiologic distinctionsCarcinogenic exposuresLower limbsLargest absolute increaseMelanomaCohort modelingAbsolute increaseIncidenceLimbLargest relative increase
1993
Age‐period‐cohort modelling of large‐bowel‐cancer incidence by anatomic sub‐site and sex in connecticut
Dubrow R, Bernstein J, Holford T. Age‐period‐cohort modelling of large‐bowel‐cancer incidence by anatomic sub‐site and sex in connecticut. International Journal Of Cancer 1993, 53: 907-913. PMID: 8473049, DOI: 10.1002/ijc.2910530607.Peer-Reviewed Original ResearchConceptsLeft colonCohort patternsTransverse colonLarge bowelCancer incidenceEtiologic distinctionsConnecticut Tumor RegistryTumor RegistrySigmoid colonCancer casesCohort modellingBirth cohortConnecticut residentsColonRectumCohort modelSexBowelIncidenceDiagnosisMalesFemalesCommon patternRegistryCohort
1992
Time trend and age-period-cohort effects on incidence of esophageal cancer in Connecticut, 1935–89
Zheng T, Mayne S, Holford T, Boyle P, Liu W, Chen Y, Mador M, Flannery J. Time trend and age-period-cohort effects on incidence of esophageal cancer in Connecticut, 1935–89. Cancer Causes & Control 1992, 3: 481-492. PMID: 1525329, DOI: 10.1007/bf00051361.Peer-Reviewed Original ResearchConceptsSquamous cell carcinomaIncidence rateCell carcinomaEsophageal cancerBirth cohortOverall age-adjusted incidence rateAge-adjusted incidence ratesConnecticut Tumor RegistryEsophageal cancer casesTime trendsEsophageal cancer ratesObserved time trendsGastric cardiaHistologic typeTumor RegistryIncident casesCancer ratesCancer casesAdenocarcinomaIncidence patternsEsophagusCancerLower thirdRegression modelingWhite malesEpidemiology of non‐Hodgkin lymphoma in connecticut 1935‐1988
Zheng T, Mayne S, Boyle P, Holford T, Liu W, Flannery J. Epidemiology of non‐Hodgkin lymphoma in connecticut 1935‐1988. Cancer 1992, 70: 840-849. PMID: 1643616, DOI: 10.1002/1097-0142(19920815)70:4<840::aid-cncr2820700420>3.0.co;2-i.Peer-Reviewed Original ResearchConceptsNon-Hodgkin lymphomaAge-adjusted incidence ratesAge-specific incidence ratesConnecticut Tumor RegistryIncidence rateYears of ageRisk factorsAge groupsCases of NHLDiffuse non-Hodgkin's lymphomaAnalytical epidemiologic studiesHigh incidence rateBirth cohort effectsOlder age groupsRecent birth cohortsReports of increasesLymph nodesTumor RegistryHistologic subtypeCohort examinationNHL casesAnatomic sitesEpidemiologic studiesMortality rateBirth cohortA reversal in the long‐term increase in deaths attributable to malignant melanoma
Roush G, McKay L, Holford T. A reversal in the long‐term increase in deaths attributable to malignant melanoma. Cancer 1992, 69: 1714-1720. PMID: 1551056, DOI: 10.1002/1097-0142(19920401)69:7<1714::aid-cncr2820690712>3.0.co;2-z.Peer-Reviewed Original Research
1988
Patterns of invasive melanoma in the connecticut tumor registry. Is the long‐term increase real?
Roush G, Schymura M, Holford T. Patterns of invasive melanoma in the connecticut tumor registry. Is the long‐term increase real? Cancer 1988, 61: 2586-2595. PMID: 3365679, DOI: 10.1002/1097-0142(19880615)61:12<2586::aid-cncr2820611233>3.0.co;2-2.Peer-Reviewed Original ResearchConceptsConnecticut Tumor RegistryProportion of casesIncidence rateTumor RegistryCase ascertainmentBirth cohortPopulation-based incidence dataInvasive cutaneous malignant melanomaPeriod of diagnosisCutaneous malignant melanomaPatterns of changeMalignant melanomaInvasive melanomaCohort curvesAge groupsDisease riskAnalysis of ageIncidence dataMelanomaRegistryCohortDiagnosisArtifactual changesAscertainmentLong-term increase
1987
Time and age trends for sinonasal cancer in connecticut incidence and US mortality rates
Roush G, Schymura M, Stevenson J, Holford T. Time and age trends for sinonasal cancer in connecticut incidence and US mortality rates. Cancer 1987, 60: 422-428. PMID: 3594381, DOI: 10.1002/1097-0142(19870801)60:3<422::aid-cncr2820600324>3.0.co;2-r.Peer-Reviewed Original ResearchConceptsUS mortality ratesSinonasal cancerMortality rateBirth cohortMortality dataPostmenopausal age groupFemale breast cancerPopulation-based ratesUS mortality dataAge distributionClemmesen's hookCigarette smokingNongynecologic malignanciesEtiologic roleSex hormonesBreast cancerAge 50Male subjectsAge groupsFemale subjectsIncidence dataCohortAge rangeCancerIncidence
1985
Risk for cutaneous melanoma in recent Connecticut birth cohorts.
Roush G, Schymura M, Holford T. Risk for cutaneous melanoma in recent Connecticut birth cohorts. American Journal Of Public Health 1985, 75: 679-82. PMID: 4003640, PMCID: PMC1646211, DOI: 10.2105/ajph.75.6.679.Peer-Reviewed Original Research