2012
Chapter 4: Development of the Counterfactual Smoking Histories Used to Assess the Effects of Tobacco Control
Holford TR, Clark L. Chapter 4: Development of the Counterfactual Smoking Histories Used to Assess the Effects of Tobacco Control. Risk Analysis 2012, 32: s39-s50. PMID: 22882891, PMCID: PMC3490210, DOI: 10.1111/j.1539-6924.2011.01759.x.Peer-Reviewed Original ResearchConceptsTobacco controlNational Health Interview SurveyLung cancer mortalityNumber of cigarettesLung cancer modelHealth Interview SurveySurveillance Modeling NetworkSurgeon General's ReportSmoking historyCessation ratesCigarette smokingCancer mortalityCancer modelCancer interventionInterview SurveySmokingPublic healthCigarettesReportControl programsGeneral's ReportControlMortalityWomenImpact of Reduced Tobacco Smoking on Lung Cancer Mortality in the United States During 1975–2000
Moolgavkar SH, Holford TR, Levy DT, Kong CY, Foy M, Clarke L, Jeon J, Hazelton WD, Meza R, Schultz F, McCarthy W, Boer R, Gorlova O, Gazelle GS, Kimmel M, McMahon PM, de Koning HJ, Feuer EJ. Impact of Reduced Tobacco Smoking on Lung Cancer Mortality in the United States During 1975–2000. Journal Of The National Cancer Institute 2012, 104: 541-548. PMID: 22423009, PMCID: PMC3317881, DOI: 10.1093/jnci/djs136.Peer-Reviewed Original ResearchConceptsLung cancer deathsLung cancer mortalityCancer deathSmoking behaviorCancer mortalityMajor public health problemTobacco controlPublic health problemTobacco control strategiesNumber of deathsSmoking historyTobacco smokingLung cancerGroups of investigatorsBirth cohortHealth problemsFirst reportSmokingMortalityDeathUnited StatesWomenMenCohortCancer
2006
Effect of Fetal Sex on Airway Lability in Pregnant Women With Asthma
Kwon H, Belanger K, Holford T, Bracken M. Effect of Fetal Sex on Airway Lability in Pregnant Women With Asthma. Obstetrical & Gynecological Survey 2006, 61: 430-431. DOI: 10.1097/01.ogx.0000224586.71900.93.Peer-Reviewed Original Research
2003
Glutathione S-transferase M1 and T1 genetic polymorphisms, alcohol consumption and breast cancer risk
Zheng T, Holford T, Zahm S, Owens P, Boyle P, Zhang Y, Zhang B, Wise J, Stephenson L, Ali-Osman F. Glutathione S-transferase M1 and T1 genetic polymorphisms, alcohol consumption and breast cancer risk. British Journal Of Cancer 2003, 88: 58-62. PMID: 12556960, PMCID: PMC2376773, DOI: 10.1038/sj.bjc.6600708.Peer-Reviewed Original ResearchConceptsBreast cancer riskGSTT1 null genotypeCancer riskAlcohol consumptionGST genotypesBreast cancerPostmenopausal womenGenetic polymorphismsIncident breast cancer patientsGlutathione S-transferase M1Breast cancer patientsT1 genetic polymorphismsCase-control studyGSTT1 genetic polymorphismsGlutathione S-transferaseS-transferase M1Cancer patientsEffect modificationGSTM1 genotypeHigh riskNew Haven CountyYounger ageCancerWomenRisk
2001
Lactation and breast cancer risk: a case–control study in Connecticut
Zheng T, Holford T, Mayne S, Owens P, Zhang Y, Zhang B, Boyle P, Zahm S. Lactation and breast cancer risk: a case–control study in Connecticut. British Journal Of Cancer 2001, 84: 1472-1476. PMID: 11384096, PMCID: PMC2363665, DOI: 10.1054/bjoc.2001.1793.Peer-Reviewed Original ResearchConceptsBreast cancer riskBreast cancerCancer riskIncident breast cancer casesMajor risk factorCase-control studyBreast cancer casesRisk reductionMenopausal statusParous womenPostmenopausal womenInverse associationRisk factorsCancer casesStudy interviewersFurther stratificationFirst childWomenStructured questionnaireLifetime durationCancerRiskLactationChildrenBreastfeeding
1998
Spontaneous Abortion and Exposure to Electric Blankets and Heated Water Beds
Belanger K, Leaderer B, Hellenbrand K, Holford T, McSharry J, Power M, Bracken M. Spontaneous Abortion and Exposure to Electric Blankets and Heated Water Beds. Epidemiology 1998, 9: 36-42. PMID: 9430266, DOI: 10.1097/00001648-199801000-00009.Peer-Reviewed Original ResearchConceptsElectric blanket useSpontaneous abortionPregnancy lossBlanket useEarly pregnancy lossHeated water bedsTime of conceptionMonth of conceptionWire code categoriesWeeks' gestationProspective studyEarly pregnancyUnadjusted analysesBed useGreater riskPregnancyAbortionDose responseWomenRiskElectric bedElectric blanketExposureSlight increaseGestation
1995
Measurement of Exposure to Environmental Tobacco Smoke in Pregnant Women
O'Connor T, Holford T, Leaderer B, Hammond S, Bracken M. Measurement of Exposure to Environmental Tobacco Smoke in Pregnant Women. American Journal Of Epidemiology 1995, 142: 1315-1321. PMID: 7503052, DOI: 10.1093/oxfordjournals.aje.a117599.Peer-Reviewed Original ResearchConceptsUrine cotinineEnvironmental tobacco smokePregnant womenTobacco smokeWork exposureAir nicotine concentrationsSelf-reported exposurePersonal air monitorsExposure assessment methodsAir nicotineMeasurement of exposureHome exposureCotinineNicotine concentrationsExposure classificationWomenCohen's kappaExposureSpearman rank-order correlation coefficientAir monitorsRank-order correlation coefficientKappaSocial exposureSmokeHigh levels
1992
A reversal in the long‐term increase in deaths attributable to malignant melanoma
Roush G, McKay L, Holford T. A reversal in the long‐term increase in deaths attributable to malignant melanoma. Cancer 1992, 69: 1714-1720. PMID: 1551056, DOI: 10.1002/1097-0142(19920401)69:7<1714::aid-cncr2820690712>3.0.co;2-z.Peer-Reviewed Original Research
1989
Age, period and cohort effects on the risk of major depression: results from five United States communities
Wickramaratne P, Weissman M, Leaf P, Holford T. Age, period and cohort effects on the risk of major depression: results from five United States communities. Journal Of Clinical Epidemiology 1989, 42: 333-343. PMID: 2723694, DOI: 10.1016/0895-4356(89)90038-3.Peer-Reviewed Original ResearchConceptsMajor depressionBirth cohortEpidemiologic Catchment Area studyYears of ageCatchment Area StudySuccessive birth cohortsLinear cohort effectCohort effectsPeriod of onsetPeriod effectsUnited States communitiesCohortDepressionAffected individualsCohort modelAgeWomenProbability sampleU.S. communitiesAPC modelMenOnset
1988
Exposure to Organic Solvents and Hypertensive Disorders of Pregnancy
Eskenazi B, Bracken M, Holford T, Grady J. Exposure to Organic Solvents and Hypertensive Disorders of Pregnancy. American Journal Of Industrial Medicine 1988, 14: 177-188. PMID: 3207103, DOI: 10.1002/ajim.4700140208.Peer-Reviewed Original ResearchConceptsHypertensive disordersPregnancy complicationsAdverse pregnancy complicationsDisorders of pregnancyPoor neonatal growthNeed of replicationCardiovascular complicationsVaginal bleedingCesarean sectionRenal diseaseGlomerular lesionsNeonatal growthComplicationsLarger sample sizePregnancySolvent exposureWomenHypertensionPreeclampsiaProteinuriaDisordersEdemaExposureSample sizeAdditional support
1986
Risk of Late First and Second Trimester Miscarriage After Induced Abortion
Bracken M, Bryce-Buchanan C, Srisuphan W, Holford T, Silten R. Risk of Late First and Second Trimester Miscarriage After Induced Abortion. American Journal Of Perinatology 1986, 3: 84-91. PMID: 3964388, DOI: 10.1055/s-2007-999839.Peer-Reviewed Original ResearchConceptsFirst prenatal visitSecond trimester miscarriagePrivate obstetric practicesLate miscarriagePrenatal visitFirst pregnancySecond pregnancySecond trimesterSubsequent miscarriageTrimester miscarriagePregnancy historyObstetric practiceInduced abortionMiscarriagePregnancyWomenAbortionRiskLate FirstTrimesterCohortVisitsLOW BIRTH WEIGHT IN PREGNANCIES FOLLOWING INDUCED ABORTION: NO EVIDENCE FOR AN ASSOCIATION1
BRACKEN M, HELLENBRAND K, HOLFORD T, BRYCE-BUCHANAN C. LOW BIRTH WEIGHT IN PREGNANCIES FOLLOWING INDUCED ABORTION: NO EVIDENCE FOR AN ASSOCIATION1. American Journal Of Epidemiology 1986, 123: 604-613. PMID: 3953539, DOI: 10.1093/oxfordjournals.aje.a114280.Peer-Reviewed Original ResearchConceptsLow birth weightMean birth weightFirst pregnancyBirth weightSecond pregnancyInduced abortionLow birth weight newbornsLow birth weight rateAntecedent pregnancyWeight newbornsSubsequent pregnancyAbortion complicationsVacuum aspirationPrior abortionPregnancyAbortionWeight rateSimilar ratesMonthsWomenDeliveryRiskCurettageComplicationsGestation
1985
ESTROGEN REPLACEMENT THERAPY AND FIBROCYSTIC BREAST DISEASE IN POSTMENOPAUSAL WOMEN1
BERKOWITZ G, KELSEY J, HOLFORD T, LIVOLSI V, MERINO M, BECK G, ORT S, O'CONNOR T, WHITE C. ESTROGEN REPLACEMENT THERAPY AND FIBROCYSTIC BREAST DISEASE IN POSTMENOPAUSAL WOMEN1. American Journal Of Epidemiology 1985, 121: 238-245. PMID: 4014118, DOI: 10.1093/oxfordjournals.aje.a113994.Peer-Reviewed Original ResearchConceptsFibrocystic breast diseaseEstrogen replacement therapyBreast diseaseReplacement therapyPostmenopausal womenHospital-based case-control studyMedical care utilizationPossible risk factorsCase-control studyDuration of useOdds of diseasePostmenopausal women1Care utilizationMenopausal estrogensExcess oddsRisk factorsSurgical conditionsTherapyDiseasePositive associationMore yearsWomenOddsAssociationEstrogenMenarcheal age and habitual miscarriage: evidence for an association
Bracken M, Bryce-Buchanan C, Stilten R, Holford T. Menarcheal age and habitual miscarriage: evidence for an association. Annals Of Human Biology 1985, 12: 525-531. PMID: 4091507, DOI: 10.1080/03014468500008101.Peer-Reviewed Original Research
1984
Exogenous hormone use and fibrocystic breast disease by histopathologic component
Berkowitz G, Kelsey J, Livolsi V, Merino M, Holford T, Hildreth N, Ort S, O'Connor T, White C. Exogenous hormone use and fibrocystic breast disease by histopathologic component. International Journal Of Cancer 1984, 34: 443-449. PMID: 6490201, DOI: 10.1002/ijc.2910340403.Peer-Reviewed Original ResearchConceptsFibrocystic breast diseaseEstrogen replacement therapyBreast diseaseGross cystsReplacement therapyHospital-based case-control studyExogenous hormone useOral contraceptive usePost-menopausal womenCase-control studyPostmenopausal womenPremenopausal womenHormone useOral contraceptivesEpithelial atypiaControl womenPapillary hyperplasiaBiopsy specimensFibrocystic lesionsSurgical conditionsContraceptive useHistopathologic componentsWomenIncreased occurrenceDiseaseAn epidemiological study of acute prolapsed cervical intervertebral disc.
Kelsey J, Githens P, Walter S, Southwick W, Weil U, Holford T, Ostfeld A, Calogero J, O'Connor T, White A. An epidemiological study of acute prolapsed cervical intervertebral disc. Journal Of Bone And Joint Surgery 1984, 66: 907-14. PMID: 6736091, DOI: 10.2106/00004623-198466060-00011.Peer-Reviewed Original ResearchConceptsCervical intervertebral discsCervical discEpidemiological studiesOnset of symptomsNumber of pregnanciesIntervertebral discBorderline statistical significanceSmoking cigarsLive birthsFrequent liftingFourth decadeAge groupsStatistical significanceHigh heelsCertain sportsPositive associationFrequent divingPregnancySymptomsNeckDiagnosisWomenORAL CONTRACEPTIVE USE AND FIBROCYSTIC BREAST DISEASE AMONG PRE- AND POSTMENOPAUSAL WOMEN1
BERKOWITZ G, KELSEY J, LIVOLSI V, HOLFORD T, MERINO M, ORT S, O'CONNOR T, GOLDENBERG I, WHITE C. ORAL CONTRACEPTIVE USE AND FIBROCYSTIC BREAST DISEASE AMONG PRE- AND POSTMENOPAUSAL WOMEN1. American Journal Of Epidemiology 1984, 120: 87-96. PMID: 6741927, DOI: 10.1093/oxfordjournals.aje.a113878.Peer-Reviewed Original ResearchConceptsFibrocystic breast diseaseOral contraceptive useBreast diseaseOral contraceptivesContraceptive useHospital-based case-control studyOral contraceptive exposureGeneral surgical serviceCase-control studyLong-term useContraceptive exposurePostmenopausal women1Postmenopausal womenPremenopausal womenCystic diseaseStudy groupSurgical servicesDecreased frequencyPast usersDiseaseIncreased occurrenceWomenContraceptivesNegative associationAssociation
1982
Effects of cigarette smoking, alcohol, coffee and tea consumption on preterm delivery
Berkowitz G, Holford T, Berkowitz R. Effects of cigarette smoking, alcohol, coffee and tea consumption on preterm delivery. Early Human Development 1982, 7: 239-250. PMID: 7160334, DOI: 10.1016/0378-3782(82)90086-x.Peer-Reviewed Original ResearchConceptsPreterm deliveryMothers of singletonsTea consumptionTerm infantsCigarette smokingRisk factorsYale-New Haven HospitalHeavy tea consumptionPossible risk factorsCase-control studyHeavy alcohol consumptionPreterm infantsMore cigarettesMore cupsCoffee drinkingAlcohol consumptionInfantsSmokingSignificant relationWomenDeliveryMothersRiskDaysSingletonsA CASE-CONTROL STUDY OF CANCER OF THE ENDOMETRIUM
KELSEY J, LIVOLSI V, HOLFORD T, FISCHER D, MOSTOW E, SCHWARTZ P, O'CONNOR T, WHITE C. A CASE-CONTROL STUDY OF CANCER OF THE ENDOMETRIUM. American Journal Of Epidemiology 1982, 116: 333-342. PMID: 7114042, DOI: 10.1093/oxfordjournals.aje.a113417.Peer-Reviewed Original ResearchConceptsCase-control studyEndometrial cancerHospital-based case-control studyEstrogen replacement therapyOral contraceptivesDecreased riskReplacement therapyElevated riskOlder ageCancerStatistical significanceWomenRiskNulliparityOverweightMenopauseEndometriumPregnancyContraceptivesTherapyEpidemiologyAN EPIDEMIOLOGIC STUDY OF HIP FRACTURE IN POSTMENOPAUSAL WOMEN
KREIGER N, KELSEY J, HOLFORD T, O'CONNOR T. AN EPIDEMIOLOGIC STUDY OF HIP FRACTURE IN POSTMENOPAUSAL WOMEN. American Journal Of Epidemiology 1982, 116: 141-148. PMID: 7102649, DOI: 10.1093/oxfordjournals.aje.a113388.Peer-Reviewed Original Research