2014
Tobacco Control and the Reduction in Smoking-Related Premature Deaths in the United States, 1964-2012
Holford TR, Meza R, Warner KE, Meernik C, Jeon J, Moolgavkar SH, Levy DT. Tobacco Control and the Reduction in Smoking-Related Premature Deaths in the United States, 1964-2012. JAMA 2014, 311: 164-171. PMID: 24399555, PMCID: PMC4056770, DOI: 10.1001/jama.2013.285112.Peer-Reviewed Original ResearchConceptsEffect of smokingAge 40 yearsSmoking-related mortalityYears of lifeTobacco controlPremature deathSmoking historySmoking-related premature deathsNational Health Interview SurveyCigarette smoking exposureSmoking-related deathsCigarette smoking historyFirst Surgeon General's reportLife expectancyMortality rate ratiosNational mortality ratesUS adult populationHealth Interview SurveyOverall health outcomesSurgeon General's ReportPublic health achievementsSmoking exposurePrimary outcomeSmoking statusCigarette smoking
2000
A Randomized Controlled Trial of Auricular Acupuncture for Cocaine Dependence
Avants S, Margolin A, Holford T, Kosten T. A Randomized Controlled Trial of Auricular Acupuncture for Cocaine Dependence. JAMA Internal Medicine 2000, 160: 2305-2312. PMID: 10927727, DOI: 10.1001/archinte.160.15.2305.Peer-Reviewed Original ResearchConceptsAuricular acupunctureCocaine dependenceCocaine addictionOpiate dependent populationUrine toxicology screenMethadone-maintained patientsCocaine-negative urine samplesDrug treatment facilitiesPrimary outcomeControlled TrialsToxicology screenTreatment modalitiesTreat sampleEffective treatmentUrine dataAcupunctureTreatment sessionsCocaine useRelaxation controlUrine samplesPatientsLongitudinal analysisTreatmentFurther investigationControl condition
1999
A Multicomponent Intervention to Prevent Delirium in Hospitalized Older Patients
Inouye S, Bogardus S, Charpentier P, Leo-Summers L, Acampora D, Holford T, Cooney L. A Multicomponent Intervention to Prevent Delirium in Hospitalized Older Patients. New England Journal Of Medicine 1999, 340: 669-676. PMID: 10053175, DOI: 10.1056/nejm199903043400901.Peer-Reviewed Original ResearchConceptsSeverity of deliriumRisk factorsCognitive impairmentRecurrence rateIntervention groupRisk factor intervention strategyHearing impairmentVisual impairmentHospitalized Older PatientsPatients 70 yearsPrevention of deliriumUsual care unitsUsual care groupGeneral medicine serviceEffective treatment strategiesDuration of episodesPrevent DeliriumOlder patientsRate of usePrimary outcomeSleep medicationPoor outcomePrimary preventionPatient's deliriumTeaching hospital