2003
Glutathione S-transferase M1 and T1 genetic polymorphisms, alcohol consumption and breast cancer risk
Zheng T, Holford T, Zahm S, Owens P, Boyle P, Zhang Y, Zhang B, Wise J, Stephenson L, Ali-Osman F. Glutathione S-transferase M1 and T1 genetic polymorphisms, alcohol consumption and breast cancer risk. British Journal Of Cancer 2003, 88: 58-62. PMID: 12556960, PMCID: PMC2376773, DOI: 10.1038/sj.bjc.6600708.Peer-Reviewed Original ResearchConceptsBreast cancer riskGSTT1 null genotypeCancer riskAlcohol consumptionGST genotypesBreast cancerPostmenopausal womenGenetic polymorphismsIncident breast cancer patientsGlutathione S-transferase M1Breast cancer patientsT1 genetic polymorphismsCase-control studyGSTT1 genetic polymorphismsGlutathione S-transferaseS-transferase M1Cancer patientsEffect modificationGSTM1 genotypeHigh riskNew Haven CountyYounger ageCancerWomenRisk
2002
Radiation exposure from diagnostic and therapeutic treatments and risk of breast cancer
Zheng T, Holford TR, Mayne ST, Luo J, Owens PH, Zhang B, Zhang W, Zhang Y. Radiation exposure from diagnostic and therapeutic treatments and risk of breast cancer. European Journal Of Cancer Prevention 2002, 11: 229-235. PMID: 12131656, DOI: 10.1097/00008469-200206000-00006.Peer-Reviewed Original ResearchConceptsBreast cancerTherapeutic radiation treatmentRadiation treatmentOdds ratioTherapeutic radiationSkin problemsBreast cancer risk factorsRadiation exposureCancer risk factorsBreast cancer riskCase-control studyDiagnostic X-ray exposurePostmenopausal womenRisk factorsCancer riskHigh riskYounger ageTherapeutic treatmentCancerDiagnostic X-raysPerson interviewsTreatmentX-ray exposureRiskStructured questionnaire
2001
Restricted activity among community-living older persons: incidence, precipitants, and health care utilization.
Gill T, Desai M, Gahbauer E, Holford T, Williams C. Restricted activity among community-living older persons: incidence, precipitants, and health care utilization. Annals Of Internal Medicine 2001, 135: 313-21. PMID: 11529694, DOI: 10.7326/0003-4819-135-5-200109040-00007.Peer-Reviewed Original ResearchConceptsCommunity-living older personsHealth care utilizationCare utilizationRestricted activityOlder personsProspective cohort studyEmergency department visitsMonthly telephone interviewsPhysician office visitsLarge health planYears of ageHealth-related problemsCohort studyDepartment visitsHospital admissionOffice visitsFunctional statusMedical attentionHigh riskHealth plansTelephone interviewsMonthsConsecutive monthsEpisodesDisability
1992
The Genetic Epidemiology of Second Primary Breast Cancer*
Bernstein J, Thompson W, Risch N, Holford T. The Genetic Epidemiology of Second Primary Breast Cancer*. American Journal Of Epidemiology 1992, 136: 937-948. PMID: 1456270, DOI: 10.1093/oxfordjournals.aje.a116566.Peer-Reviewed Original ResearchConceptsSecond primary breast cancerPrimary breast cancerContralateral breast cancerFirst primary breast cancerFirst-degree relativesBreast cancerFamily historyOvarian cancerMulti-center population-based case-control studyPopulation-based case-control studyAge-adjusted rate ratioSteroid Hormone StudyBilateral breast cancerEnd Results ProgramRate ratioCase-control studyCorresponding rate ratiosContralateral breastEndometrial cancerProspective studyResults ProgramSecond primaryCohort membersHigh riskHormone Study
1984
Acute Prolapsed Lumbar Intervertebral Disc An Epidemiologic Study with Special Reference to Driving Automobiles and Cigarette Smoking
KELSEY J, GITHENS P, O'CONNER T, WEIL U, CALOGERO J, HOLFORD T, WHITE A, WALTER S, OSTFELD A, SOUTHWICK W. Acute Prolapsed Lumbar Intervertebral Disc An Epidemiologic Study with Special Reference to Driving Automobiles and Cigarette Smoking. Spine 1984, 9: 608-613. PMID: 6495031, DOI: 10.1097/00007632-198409000-00012.Peer-Reviewed Original ResearchConceptsCigarette smokingAverage riskNumber of pregnanciesPossible etiologic significanceCase-control studyEpidemiologic case-control studyRatio of menLumbar intervertebral discsNonoccupational factorsFemale ratioRisk factorsEpidemiologic studiesHigh riskSurgical casesEtiologic significanceNumber of childrenLumbar discIntervertebral discHigh heelsSmokingRiskNumber of hoursPast yearPregnancySurgeryAn epidemiologic study of lifting and twisting on the job and risk for acute prolapsed lumbar intervertebral disc
Kelsey J, Githens P, White A, Holford T, Walter S, O'Connor T, Ostfeld A, Weil U, Southwick W, Calogero J. An epidemiologic study of lifting and twisting on the job and risk for acute prolapsed lumbar intervertebral disc. Journal Of Orthopaedic Research® 1984, 2: 61-66. PMID: 6491800, DOI: 10.1002/jor.1100020110.Peer-Reviewed Original Research