2024
Modeling cigarette smoking exposure in subsets of the population
Holford T. Modeling cigarette smoking exposure in subsets of the population. Open Access Government 2024, 44: 186-187. DOI: 10.56367/oag-044-11540.Peer-Reviewed Original ResearchCigarette smokingClean air lawsPublic health interventionsPublic health challengeTobacco controlHealth interventionsTobacco useGeographic disparitiesAir lawsPopulation's understandingHealth challengesSmoke exposureEffects of cigarette smokingShorten lifePublic healthSmokingLevels of exposureCigaretteProtect public healthTobaccoNational levelLegal ageCigarette smoke exposureIncreased costsPopulationCigarette smoking focus: A modeling approach for estimating the impact of health programs
Holford T. Cigarette smoking focus: A modeling approach for estimating the impact of health programs. Open Access Government 2024, 43: 82-83. DOI: 10.56367/oag-043-11502.Peer-Reviewed Original Research
2023
Smoking Histories by State in the U.S.
Holford T, McKay L, Jeon J, Tam J, Cao P, Fleischer N, Levy D, Meza R. Smoking Histories by State in the U.S. American Journal Of Preventive Medicine 2023, 64: s42-s52. PMID: 36653233, PMCID: PMC11186469, DOI: 10.1016/j.amepre.2022.08.018.Peer-Reviewed Original ResearchConceptsPack yearsSmoking historySmoking prevalenceBirth cohortSmoking initiationNational Health Interview SurveyMean smoking durationHealth Interview SurveyTobacco Use SupplementRecent birth cohortsTobacco control policiesCessation probabilitiesCigarette smokingSmoking trendsSmoking durationSmoking ratesState-specific trendsPrevalenceTobacco controlInterview SurveyCohortCessationDurationInitiationYears
2020
Modeling factors affecting age, period and cohort trends
Holford T. Modeling factors affecting age, period and cohort trends. 2020, 117-141. DOI: 10.4324/9780429056819-7.Peer-Reviewed Original ResearchAnalytical epidemiological studiesUnderstanding of etiologyCigarette smokingLung cancerEtiology of diseaseEpidemiological studiesCarcinogenesis modelDisease trendsCohort scaleCohort frameworkHealth careDiseaseExposure dataPopulation ratesCohort modelCohort trendsSmokingAgeEtiologyU.S. malesTemporal trendsEarly stepsCancerPeriodCare
2014
Tobacco Control and the Reduction in Smoking-Related Premature Deaths in the United States, 1964-2012
Holford TR, Meza R, Warner KE, Meernik C, Jeon J, Moolgavkar SH, Levy DT. Tobacco Control and the Reduction in Smoking-Related Premature Deaths in the United States, 1964-2012. JAMA 2014, 311: 164-171. PMID: 24399555, PMCID: PMC4056770, DOI: 10.1001/jama.2013.285112.Peer-Reviewed Original ResearchConceptsEffect of smokingAge 40 yearsSmoking-related mortalityYears of lifeTobacco controlPremature deathSmoking historySmoking-related premature deathsNational Health Interview SurveyCigarette smoking exposureSmoking-related deathsCigarette smoking historyFirst Surgeon General's reportLife expectancyMortality rate ratiosNational mortality ratesUS adult populationHealth Interview SurveyOverall health outcomesSurgeon General's ReportPublic health achievementsSmoking exposurePrimary outcomeSmoking statusCigarette smoking
2012
Chapter 12: Yale Lung Cancer Model
Holford TR, Ebisu K, McKay L, Oh C, Zheng T. Chapter 12: Yale Lung Cancer Model. Risk Analysis 2012, 32: s151-s165. PMID: 22882886, PMCID: PMC3662537, DOI: 10.1111/j.1539-6924.2011.01754.x.Peer-Reviewed Original ResearchConceptsLung cancer deathsCarcinogenesis modelCancer deathLung cancer incidenceLung cancer modelTwo-stage clonal expansion modelCigarette smokingCancer incidenceCancer modelTobacco controlClonal expansion modelPopulation ratesCohort modelSmokingDeathHarmful effectsPopulation dataTemporal trendsMortalityObserved numberIncidenceControlChapter 4: Development of the Counterfactual Smoking Histories Used to Assess the Effects of Tobacco Control
Holford TR, Clark L. Chapter 4: Development of the Counterfactual Smoking Histories Used to Assess the Effects of Tobacco Control. Risk Analysis 2012, 32: s39-s50. PMID: 22882891, PMCID: PMC3490210, DOI: 10.1111/j.1539-6924.2011.01759.x.Peer-Reviewed Original ResearchConceptsTobacco controlNational Health Interview SurveyLung cancer mortalityNumber of cigarettesLung cancer modelHealth Interview SurveySurveillance Modeling NetworkSurgeon General's ReportSmoking historyCessation ratesCigarette smokingCancer mortalityCancer modelCancer interventionInterview SurveySmokingPublic healthCigarettesReportControl programsGeneral's ReportControlMortalityWomen
2003
Cigarette smoking and risk of non-Hodgkin lymphoma subtypes among women
Morton L, Holford T, Leaderer B, Boyle P, Zahm S, Zhang Y, Flynn S, Tallini G, Zhang B, Owens P, Zheng T. Cigarette smoking and risk of non-Hodgkin lymphoma subtypes among women. British Journal Of Cancer 2003, 89: 2087-2092. PMID: 14647142, PMCID: PMC2376853, DOI: 10.1038/sj.bjc.6601388.Peer-Reviewed Original ResearchConceptsNon-Hodgkin lymphomaCumulative lifetime exposureCurrent smoking statusCigarette smokingNHL subtypesFollicular lymphomaLifetime exposurePopulation-based case-control studyRisk of NHLEtiology of NHLNon-Hodgkin lymphoma subtypesDuration of smokingIntensity of smokingPrevious epidemiologic studiesCase-control studyPopulation-based controlsHistologic typeSmoking statusIncident casesTumor gradeLymphoma subtypesEpidemiologic studiesSmokingImmunologic typeLymphoma
1996
Time trend and age‐period‐cohort effect on incidence of bladder cancer in Connecticut, 1935–1992
Zheng T, Holford T, Chen Y, Z. J, Mayne S, Liu W, Flannery J, Boyle P. Time trend and age‐period‐cohort effect on incidence of bladder cancer in Connecticut, 1935–1992. International Journal Of Cancer 1996, 68: 172-176. PMID: 8900423, DOI: 10.1002/(sici)1097-0215(19961009)68:2<172::aid-ijc5>3.0.co;2-v.Peer-Reviewed Original ResearchConceptsUrinary bladder cancerMajor risk factorBladder cancerRisk factorsIncidence rateBirth-cohort patternSmoking-related cancersAnalytical epidemiologic studiesTime trendsTobacco smokingCigarette smokingLung cancerOccupational exposureEpidemiologic studiesCancerMarked increaseSmokingCohort effectsMalesRecent studiesCurrent studyFemalesIncidenceStudyConnecticutA MODEL FOR THE EFFECT OF CIGARETTE SMOKING ON LUNG CANCER INCIDENCE IN CONNECTICUT
HOLFORD T, ZHANG Z, ZHENG T, MCKAY L. A MODEL FOR THE EFFECT OF CIGARETTE SMOKING ON LUNG CANCER INCIDENCE IN CONNECTICUT. Statistics In Medicine 1996, 15: 565-580. PMID: 8731001, DOI: 10.1002/(sici)1097-0258(19960330)15:6<565::aid-sim185>3.0.co;2-t.Peer-Reviewed Original ResearchConceptsLung cancer incidenceCancer incidenceIncidence rateLung cancer incidence ratesLung cancer incidence trendsEffect of smokingCancer incidence ratesCancer incidence trendsCohort studyCurrent smokersLevel of exposureMale smokersSmoking historySmoking subgroupsSmoking informationCigarette smokingMean durationSmoking prevalenceIncidence trendsSmokersSmokingPrevalenceCohort effectsAge distributionIncidence
1987
Time and age trends for sinonasal cancer in connecticut incidence and US mortality rates
Roush G, Schymura M, Stevenson J, Holford T. Time and age trends for sinonasal cancer in connecticut incidence and US mortality rates. Cancer 1987, 60: 422-428. PMID: 3594381, DOI: 10.1002/1097-0142(19870801)60:3<422::aid-cncr2820600324>3.0.co;2-r.Peer-Reviewed Original ResearchConceptsUS mortality ratesSinonasal cancerMortality rateBirth cohortMortality dataPostmenopausal age groupFemale breast cancerPopulation-based ratesUS mortality dataAge distributionClemmesen's hookCigarette smokingNongynecologic malignanciesEtiologic roleSex hormonesBreast cancerAge 50Male subjectsAge groupsFemale subjectsIncidence dataCohortAge rangeCancerIncidence
1984
Acute Prolapsed Lumbar Intervertebral Disc An Epidemiologic Study with Special Reference to Driving Automobiles and Cigarette Smoking
KELSEY J, GITHENS P, O'CONNER T, WEIL U, CALOGERO J, HOLFORD T, WHITE A, WALTER S, OSTFELD A, SOUTHWICK W. Acute Prolapsed Lumbar Intervertebral Disc An Epidemiologic Study with Special Reference to Driving Automobiles and Cigarette Smoking. Spine 1984, 9: 608-613. PMID: 6495031, DOI: 10.1097/00007632-198409000-00012.Peer-Reviewed Original ResearchConceptsCigarette smokingAverage riskNumber of pregnanciesPossible etiologic significanceCase-control studyEpidemiologic case-control studyRatio of menLumbar intervertebral discsNonoccupational factorsFemale ratioRisk factorsEpidemiologic studiesHigh riskSurgical casesEtiologic significanceNumber of childrenLumbar discIntervertebral discHigh heelsSmokingRiskNumber of hoursPast yearPregnancySurgery
1982
Effects of cigarette smoking, alcohol, coffee and tea consumption on preterm delivery
Berkowitz G, Holford T, Berkowitz R. Effects of cigarette smoking, alcohol, coffee and tea consumption on preterm delivery. Early Human Development 1982, 7: 239-250. PMID: 7160334, DOI: 10.1016/0378-3782(82)90086-x.Peer-Reviewed Original ResearchConceptsPreterm deliveryMothers of singletonsTea consumptionTerm infantsCigarette smokingRisk factorsYale-New Haven HospitalHeavy tea consumptionPossible risk factorsCase-control studyHeavy alcohol consumptionPreterm infantsMore cigarettesMore cupsCoffee drinkingAlcohol consumptionInfantsSmokingSignificant relationWomenDeliveryMothersRiskDaysSingletonsCLINICAL CHARACTERISTICS AND CIGARETTE SMOKING IN RELATION TO PROGNOSIS OF ANGINA PECTORIS IN FRAMINGHAM
HUBERT H, HOLFORD T, KANNEL W. CLINICAL CHARACTERISTICS AND CIGARETTE SMOKING IN RELATION TO PROGNOSIS OF ANGINA PECTORIS IN FRAMINGHAM. American Journal Of Epidemiology 1982, 115: 231-242. PMID: 7058782, DOI: 10.1093/oxfordjournals.aje.a113295.Peer-Reviewed Original ResearchConceptsAngina pectorisBlood pressureAngina onsetElectrocardiographic findingsUncomplicated angina pectorisCoronary risk factorsFuture coronary eventsElevated blood pressurePowerful independent predictorCigarette smoking habitsLong-term prognosisSystolic blood pressureLong-term followYears of ageLack of associationCoronary eventsCoronary riskBaseline characteristicsSymptom onsetYounger patientsIndependent predictorsPrognostic advantageSmoking habitsAbnormal electrocardiogramCigarette smoking