2015
Practical Management of HIV-Associated Anemia in Resource-Limited Settings: Prospective Observational Evaluation of a New Mozambican Guideline
Brentlinger PE, Silva WP, Vermund SH, Valverde E, Buene M, Moon TD. Practical Management of HIV-Associated Anemia in Resource-Limited Settings: Prospective Observational Evaluation of a New Mozambican Guideline. AIDS Research And Human Retroviruses 2015, 32: 12-25. PMID: 26178574, PMCID: PMC4692124, DOI: 10.1089/aid.2015.0030.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnemiaAnthelminticsAnti-HIV AgentsAntimalarialsAntitubercular AgentsCD4 Lymphocyte CountCoinfectionDeveloping CountriesDisease ManagementFemaleHelminthiasisHemoglobinsHIV InfectionsHumansLost to Follow-UpMalaria, FalciparumMaleMozambiquePractice Guidelines as TopicProspective StudiesRural PopulationTuberculosis, PulmonaryConceptsHIV-associated anemiaAdverse drug reactionsDrug reactionsHemoglobin responseGuideline revisionsIron deficiencyLower body mass indexCo-trimoxazole prophylaxisDiscontinuation of zidovudineLaboratory-confirmed malariaProspective observational evaluationRural Zambézia ProvinceT-cell countsT-lymphocyte countsSmear-positive tuberculosisBody mass indexResource limited settingsResource-limited settingsLogistic regression modelsAnaemic HIVStudy cliniciansAntiretroviral therapyEsophageal candidiasisPresumptive treatmentAnemia management
2014
Helminth prevalence among adults in rural Kenya: a stool survey for soil-transmitted helminths and schistosomiasis in Nyanza province
Andereck JW, Kipp AM, Ondiek M, Vermund SH. Helminth prevalence among adults in rural Kenya: a stool survey for soil-transmitted helminths and schistosomiasis in Nyanza province. Transactions Of The Royal Society Of Tropical Medicine And Hygiene 2014, 108: 804-809. PMID: 25359321, DOI: 10.1093/trstmh/tru164.Peer-Reviewed Original ResearchConceptsSTH prevalenceRisk factorsSoil-transmitted helminth prevalenceHelminth prevalenceNyanza ProvinceOut-patient departmentMultivariable regression modelsSoil-transmitted helminthsStool concentration techniqueLow education levelFemale sexStool samplesStool surveyCommunity outreach eventsTrichuris trichiuraSame villagePrevalence dataOlder agePrevalenceSchistosoma mansoniSmall hospitalsShort questionnaireAdultsRural KenyaAnthelmintic drugs
2009
High Prevalence of Soil-transmitted Helminths in Western Kenya: Failure to Implement Deworming Guidelines in Rural Nyanza Province
Riesel JN, Ochieng’ F, Wright P, Vermund SH, Davidson M. High Prevalence of Soil-transmitted Helminths in Western Kenya: Failure to Implement Deworming Guidelines in Rural Nyanza Province. Journal Of Tropical Pediatrics 2009, 56: 60-62. PMID: 19502602, DOI: 10.1093/tropej/fmp043.Peer-Reviewed Original ResearchConceptsSTH infectionsSoil-transmitted helminth infectionsRural Nyanza ProvinceNyanza ProvinceSingle stool sampleRegular deworming programmeSoil-transmitted helminthsGreater morbidityRegular dewormingPrimary school-aged childrenSchool-aged childrenHigh prevalenceStool samplesHelminth infectionsDeworming programsSignificant burdenInfectionWorm infectionPrevalencePeople worldTwo-thirdsRural Kenyan villagesWestern KenyaChildrenKenyan villages
2005
Prevalence and predictors of intestinal helminth infections among human immunodeficiency virus type 1-infected adults in an urban African setting.
Modjarrad K, Zulu I, Redden DT, Njobvu L, Freedman DO, Vermund SH. Prevalence and predictors of intestinal helminth infections among human immunodeficiency virus type 1-infected adults in an urban African setting. American Journal Of Tropical Medicine And Hygiene 2005, 73: 777-82. PMID: 16222025, PMCID: PMC2749260, DOI: 10.4269/ajtmh.2005.73.777.Peer-Reviewed Original ResearchConceptsHIV-1-infected adultsIntestinal helminth infectionsHelminth infectionsUrban African settingIntestinal helminthsHuman immunodeficiency virus type 1Immunodeficiency virus type 1Detrimental immunologic effectsRoutine HIV careAfrican settingHuman immunodeficiency virusLight-intensity infectionsHIV infection ratesVirus type 1HIV careImmunologic effectsConcomitant infectionImmunodeficiency virusPrior historyHelminth diagnosisAscaris lumbricoidesHelminth statusParasitologic dataInfection rateInfectionTreatment of Intestinal Helminths Does Not Reduce Plasma Concentrations of HIV-1 RNA in Coinfected Zambian Adults
Modjarrad K, Zulu I, Redden DT, Njobvu L, Lane HC, Bentwich Z, Vermund SH. Treatment of Intestinal Helminths Does Not Reduce Plasma Concentrations of HIV-1 RNA in Coinfected Zambian Adults. The Journal Of Infectious Diseases 2005, 192: 1277-1283. PMID: 16136473, PMCID: PMC2730764, DOI: 10.1086/444543.Peer-Reviewed Original ResearchConceptsHIV-1 RNAViral loadPlasma concentrationsAntihelminthic treatmentCopies/Helminth infectionsIntestinal helminthsHigh pretreatment viral loadMedian baseline viral loadPretreatment viral loadBaseline viral loadDysfunctional immune responseIntestinal helminth infectionsHuman immunodeficiency virusMean viral loadCopies/mLHigher helminth burdensPosttreatment visitAsymptomatic adultsImmunodeficiency virusProspective studyZambian adultsUninfected groupHIV-1Immune response