2022
Protocol for the pilot quasi-experimental controlled trial of a gender-responsive implementation strategy with providers to improve HIV outcomes in Uganda
Sileo K, Wanyenze R, Anecho A, Luttinen R, Semei C, Mukasa B, Musoke W, Vermund S, Dworkin S, Dovidio J, Taylor B, Kershaw T. Protocol for the pilot quasi-experimental controlled trial of a gender-responsive implementation strategy with providers to improve HIV outcomes in Uganda. Pilot And Feasibility Studies 2022, 8: 264. PMID: 36564795, PMCID: PMC9783690, DOI: 10.1186/s40814-022-01202-0.Peer-Reviewed Original ResearchHIV care engagementHIV outcomesCare engagementViral load suppressionPilot intervention trialPatient-provider relationshipEffective clinical interventionsPreliminary evidenceEvidence-based strategiesHIV providersHIV counselingHIV disparitiesHIV treatmentIntervention trialsControl clinicsImplementation strategiesProvider outcomesClinical interventionsProvider capacityTrialsGender-responsive treatmentInterventionOutcomesPatientsTreatment
2021
Community-based health workers implementing universal access to HIV testing and treatment: lessons from South Africa and Zambia—HPTN 071 (PopART)
Viljoen L, Mainga T, Casper R, Mubekapi-Muzadaidzwa C, Wademan D, Bond V, Pliakas T, Bwalya C, Stangl A, Phiri M, Yang B, Shanaube K, Bock P, Fidler S, Hayes R, Ayles H, Hargreaves J, Hoddinott G, Seeley J, Donnell D, Floyd S, Mandla N, Bwalya J, Sabapathy K, Eshleman S, Macleod D, Moore A, Vermund S, Hauck K, Shanaube K. Community-based health workers implementing universal access to HIV testing and treatment: lessons from South Africa and Zambia—HPTN 071 (PopART). Health Policy And Planning 2021, 36: 881-890. PMID: 33963387, PMCID: PMC8227454, DOI: 10.1093/heapol/czab019.Peer-Reviewed Original ResearchConceptsCommunity-based health workersHIV testingHealth workersHIV prevention packageHPTN 071 (PopART) trialHIV epidemic controlPopulation health benefitsPopART interventionCHW interventionPrevention packageTreatment servicesIntervention staffTrial outcomesBaseline quantitative dataReferral servicesCHW retentionHealth benefitsIntervention packageProcess evaluationEpidemic controlGroup discussionsInterventionTrialsKey informant interviewsEmotional support
2020
Integrating and Interpreting Findings from the Latest Treatment as Prevention Trials
Brault MA, Spiegelman D, Abdool Karim SS, Vermund SH. Integrating and Interpreting Findings from the Latest Treatment as Prevention Trials. Current HIV/AIDS Reports 2020, 17: 249-258. PMID: 32297219, PMCID: PMC7260110, DOI: 10.1007/s11904-020-00492-4.Peer-Reviewed Original Research
2019
Treatment as Prevention: Concepts and Challenges for Reducing HIV Incidence
Brault MA, Spiegelman D, Hargreaves J, Nash D, Vermund SH. Treatment as Prevention: Concepts and Challenges for Reducing HIV Incidence. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2019, 82: s104-s112. PMID: 31658196, PMCID: PMC6820703, DOI: 10.1097/qai.0000000000002168.Peer-Reviewed Original ResearchConceptsAntiretroviral therapyHIV transmissionHIV plasma loadReducing HIV IncidenceHIV prevention trialsCommunity-level interventionsDeployable vaccineViral suppressionHIV testingHIV incidencePrevention trialsUninfected personsChronic conditionsHIV investmentsEarly treatmentTreat strategySexual partnersViral expressionTransmission riskHIVTrialsTreatmentInconsistent findingsPreventionSaharan Africa
2018
Negative associations between general self-efficacy and anxiety/depression among newly HIV-diagnosed men who have sex with men in Beijing, China
Wang N, Wang S, Qian HZ, Ruan Y, Amico KR, Vermund SH, Yin L, Qiu X, Zheng S. Negative associations between general self-efficacy and anxiety/depression among newly HIV-diagnosed men who have sex with men in Beijing, China. AIDS Care 2018, 31: 629-635. PMID: 30466302, PMCID: PMC7942229, DOI: 10.1080/09540121.2018.1549721.Peer-Reviewed Original ResearchConceptsDepression/anxietyChinese MSMLogistic regressionAnxiety/depressionBaseline survey dataNegative associationPotential confoundersClinical trialsStudy populationChinese menHIVOverall healthBaseline surveyMSMCumulative logistic regressionDepressionMenAnxietyAssociationTrialsSexLow levelsHigh levelsConfoundersRegressionAssessing Individual and Disseminated Effects in Network-Randomized Studies
Buchanan AL, Vermund SH, Friedman SR, Spiegelman D. Assessing Individual and Disseminated Effects in Network-Randomized Studies. American Journal Of Epidemiology 2018, 187: 2449-2459. PMID: 30052722, PMCID: PMC6211234, DOI: 10.1093/aje/kwy149.Peer-Reviewed Original Research
2013
Attitudes Toward HIV Pre-Exposure Prophylaxis Among Men Who Have Sex with Men in Western China
Zhang Y, Peng B, She Y, Liang H, Peng HB, Qian HZ, Vermund SH, Zhong XN, Huang A. Attitudes Toward HIV Pre-Exposure Prophylaxis Among Men Who Have Sex with Men in Western China. AIDS Patient Care And STDs 2013, 27: 137-141. PMID: 23425017, PMCID: PMC3595955, DOI: 10.1089/apc.2012.0412.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAnti-HIV AgentsAsian PeopleChinaHealth Knowledge, Attitudes, PracticeHIV InfectionsHomosexuality, MaleHumansLogistic ModelsMaleMultivariate AnalysisPatient Acceptance of Health CareSexual PartnersSexually Transmitted DiseasesSocioeconomic FactorsSurveys and QuestionnairesYoung AdultConceptsPre-exposure prophylaxisHIV pre-exposure prophylaxisUse of PrEPSelf-administered questionnaireClinical trialsChinese MSMInfection historySexual partnersHIVLower educationPrEPPredictors of willingnessProphylaxisModerate awarenessMenMSMLow incomeSexModerate incomeParticipantsMore knowledgeAIDSTrialsMonths
2011
Nurturing the Global Workforce in Clinical Research: The National Institutes of Health Fogarty International Clinical Scholars and Fellows Program
Heimburger DC, Carothers CL, Gardner P, Primack A, Warner TL, Vermund SH. Nurturing the Global Workforce in Clinical Research: The National Institutes of Health Fogarty International Clinical Scholars and Fellows Program. American Journal Of Tropical Medicine And Hygiene 2011, 85: 971-978. PMID: 22144429, PMCID: PMC3225173, DOI: 10.4269/ajtmh.2011.11-0141.Peer-Reviewed Original ResearchConceptsHealth research partnershipsChronic disease researchClinical research settingClinical trialsObservational studyGlobal health expertsClinical investigatorsInfectious diseasesClinical researchTranslational researchHealth expertsInternational investigatorsNational InstituteFogarty International Clinical Research ScholarsHealth researchClinical scholarsDisease researchGlobal health researchResearch settingsHigh-impact journalsInvestigatorsTraining opportunitiesDiseaseTrials
2010
Randomized controlled trial to improve childhood immunization adherence in rural Pakistan: redesigned immunization card and maternal education
Usman HR, Rahbar MH, Kristensen S, Vermund SH, Kirby RS, Habib F, Chamot E. Randomized controlled trial to improve childhood immunization adherence in rural Pakistan: redesigned immunization card and maternal education. Tropical Medicine And International Health 2010, 16: 334-342. PMID: 21159080, PMCID: PMC3763701, DOI: 10.1111/j.1365-3156.2010.02698.x.Peer-Reviewed Original ResearchConceptsStandard care groupMother-child pairsImmunization cardPublic health impactCare groupIntervention groupStudy groupCard groupEnd of followEducation groupDTP immunizationImmunization adherenceEPI scheduleFirst doseImmunization visitsStandard careMaternal educationStudy outcomesSubstantial dropoutHealth impactsImmunizationDTP3ChildrenDoseTrialsRethinking Prevention of HIV Type 1 Infection
Burns DN, Dieffenbach CW, Vermund SH. Rethinking Prevention of HIV Type 1 Infection. Clinical Infectious Diseases 2010, 51: 725-731. PMID: 20707698, PMCID: PMC3071685, DOI: 10.1086/655889.Peer-Reviewed Original Research
2009
HIV-prevention science at a crossroads: advances in reducing sexual risk
Vermund SH, Allen KL, Karim QA. HIV-prevention science at a crossroads: advances in reducing sexual risk. Current Opinion In HIV And AIDS 2009, 4: 266-273. PMID: 19532063, PMCID: PMC2995247, DOI: 10.1097/coh.0b013e32832c91dd.Peer-Reviewed Original ResearchConceptsRandomized clinical trialsSexual transmissionPrevention strategiesEvidence-based prevention strategiesMale circumcision trialHIV prevention scienceNew prevention toolsSpread of HIVStructural risk factorsPRO 2000Circumcision trialHIV incidenceSyndromic managementRisk factorsClinical trialsMicrobicide trialsPrevention interventionsHIVPrevention benefitsSexual riskPrevention toolTrialsCombination strategiesMore yearsGlobal pandemicWillingness to Be Circumcised for Preventing HIV among Chinese Men Who Have Sex with Men
Ruan Y, Qian HZ, Li D, Shi W, Li Q, Liang H, Yang Y, Luo F, Vermund SH, Shao Y. Willingness to Be Circumcised for Preventing HIV among Chinese Men Who Have Sex with Men. AIDS Patient Care And STDs 2009, 23: 315-321. PMID: 19335172, PMCID: PMC2743100, DOI: 10.1089/apc.2008.0199.Peer-Reviewed Original ResearchConceptsClinical trialsChinese MSMChinese menMale circumcisionEffectiveness of circumcisionLack of historyUncircumcised MSMHIV acquisitionHIV/Genital hygieneAdult circumcisionFree medical servicesTight foreskinSide effectsSexual partnersInfection riskMSMCircumcisionPreventing HIVMedical servicesTrialsMenHeterosexual menCommunity educationSex
2007
A randomized trial of the intrauterine contraceptive device vs hormonal contraception in women who are infected with the human immunodeficiency virus
Stringer EM, Kaseba C, Levy J, Sinkala M, Goldenberg RL, H. B, Matongo I, Vermund SH, Mwanahamuntu M, Stringer JS. A randomized trial of the intrauterine contraceptive device vs hormonal contraception in women who are infected with the human immunodeficiency virus. American Journal Of Obstetrics And Gynecology 2007, 197: 144.e1-144.e8. PMID: 17689627, PMCID: PMC2730754, DOI: 10.1016/j.ajog.2007.03.031.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virusIntrauterine contraceptive devicePelvic inflammatory diseaseHormonal contraceptionImmunodeficiency virusInflammatory diseasesDisease progressionContraceptive deviceRapid HIV disease progressionHIV disease progressionClinical disease progressionUrgent further studyCopper intrauterine contraceptive deviceContraceptionWomenFurther studiesDiseaseProgressionVirusPostpartumTrialsSyndromic management training for non-formal care providers in Pakistan improves quality of care for sexually transmitted diseases STD care: a randomized clinical trial.
Shah SA, Kristensen S, Memon MA, White HL, Vermund SH. Syndromic management training for non-formal care providers in Pakistan improves quality of care for sexually transmitted diseases STD care: a randomized clinical trial. The Southeast Asian Journal Of Tropical Medicine And Public Health 2007, 38: 737-48. PMID: 17883016.Peer-Reviewed Original ResearchConceptsSTD careIntervention groupCare providersControl groupRandomized clinical trialsThree-armed trialQuality of careCase management servicesSTD servicesSyndromic managementClinical trialsCondom provisionCondom useNon-formal providersExit interviewsCareTrialsGroupProvidersService deliveryManagement trainingPatientsReferralMore knowledgeMonthsThe Future of HIV Prevention: Control of Sexually Transmitted Infections and Circumcision Interventions
Sahasrabuddhe VV, Vermund SH. The Future of HIV Prevention: Control of Sexually Transmitted Infections and Circumcision Interventions. Infectious Disease Clinics Of North America 2007, 21: 241-257. PMID: 17502238, PMCID: PMC2700301, DOI: 10.1016/j.idc.2007.03.005.Peer-Reviewed Original ResearchConceptsHIV infectionGenital tract inflammationMale circumcision programsSTI treatmentCircumcision programsSymptomatic personsHIV preventionCurrent evidenceMale circumcisionCircumcision interventionsInfectionHIVSeparate trialsPreventionTreatmentResearch prioritiesInflammationPersonsControlTrialsCircumcision
2006
Correlates of Syphilis Seroreactivity Among Pregnant Women: The HIVNET 024 Trial in Malawi, Tanzania, and Zambia
Potter D, Goldenberg RL, Read JS, Wang J, Hoffman IF, Saathoff E, Kafulafula G, Aboud S, Martinson FE, Dahab M, Vermund SH. Correlates of Syphilis Seroreactivity Among Pregnant Women: The HIVNET 024 Trial in Malawi, Tanzania, and Zambia. Sexually Transmitted Diseases 2006, 33: 604-609. PMID: 16601659, PMCID: PMC2743105, DOI: 10.1097/01.olq.0000216029.00424.ae.Peer-Reviewed Original ResearchConceptsSub-Saharan African settingHistory of stillbirthCross-sectional studyMultisite clinical trialSyphilis preventionSyphilis seroprevalenceSyphilis seroreactivityAntenatal attendeesPreterm deliveryYoung HIVAntenatal HIVHIV infectionPregnant womenSyphilis screeningRisk factorsClinical trialsUlcer treatmentHigh riskHIVAge 20African settingWomenSignificant correlatesTrialsCorrelates
2005
An Intervention to Reduce Vaginal Douching Among Adolescent and Young Adult Women: A Randomized, Controlled Trial
Grimley DM, Oh MK, Desmond RA, Hook EW, Vermund SH. An Intervention to Reduce Vaginal Douching Among Adolescent and Young Adult Women: A Randomized, Controlled Trial. Sexually Transmitted Diseases 2005, 32: 752-758. PMID: 16314772, DOI: 10.1097/01.olq.0000190018.58079.05.Peer-Reviewed Original ResearchConceptsVaginal douchingYoung adult womenAdult womenIndividualized counseling sessionsTreat modelPrimary outcome measureStage of readinessSecondary outcomesIntervention groupOutcome measuresStages of changeHealthy eatingStage-matched interventionsYoung womenDouchingYoung adultsComparison groupWomenMonthsCounseling sessionsInterventionExperimental groupTrialsCessationComparison condition
2004
Priorities for Antiretroviral Therapy Research in Sub-Saharan Africa
Zulu I, Schuman P, Musonda R, Chomba E, Mwinga K, Sinkala M, Chisembele M, Mwaba P, Kasonde D, Vermund SH. Priorities for Antiretroviral Therapy Research in Sub-Saharan Africa. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2004, 36: 831-834. PMID: 15213567, PMCID: PMC2745050, DOI: 10.1097/00126334-200407010-00010.Peer-Reviewed Original ResearchConceptsAntiretroviral clinical trialsClinical trialsActive antiretroviral therapyAvailability of HAARTImpact of nonadherenceResource-constrained countriesResource-limited settingsHome-based care servicesAntiretroviral therapyPublic health contextART availabilityDrug costsClinical careTherapy researchConsensus conferenceViral resistanceResearch prioritiesCare servicesGeneric medicationsSuch trialsTherapeutic resourcesTrialsHAARTHIVUrgent research priority
2002
Effect of nevirapine toxicity on choice of perinatal HIV prevention strategies.
Stringer JS, Sinkala M, Rouse DJ, Goldenberg RL, Vermund SH. Effect of nevirapine toxicity on choice of perinatal HIV prevention strategies. American Journal Of Public Health 2002, 92: 365-6. PMID: 11867311, PMCID: PMC1447080, DOI: 10.2105/ajph.92.3.365.Peer-Reviewed Original Research
2001
Vaccine Efficacy Trials for Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome Are Feasible in the United States: A Commentary on the HIVNET Vaccine Preparedness Study
Vermund SH. Vaccine Efficacy Trials for Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome Are Feasible in the United States: A Commentary on the HIVNET Vaccine Preparedness Study. American Journal Of Epidemiology 2001, 153: 628-631. PMID: 11282788, DOI: 10.1093/aje/153.7.628.Peer-Reviewed Original Research