2024
Assessment of a screening tool to aid home-based identification of adolescents (aged 10–14) living with HIV in Zambia and South Africa: HPTN 071 (PopART) study
Chaila M, Mcleod D, Vermund S, Mbolongwe-Thornicroft M, Mbewe M, Mubekapi-Musadaidzwa C, Harper A, Schaap A, Floyd S, Hoddinott G, Hayes R, Fidler S, Ayles H, Shanaube K, Team O. Assessment of a screening tool to aid home-based identification of adolescents (aged 10–14) living with HIV in Zambia and South Africa: HPTN 071 (PopART) study. PLOS ONE 2024, 19: e0266573. PMID: 38363733, PMCID: PMC10871489, DOI: 10.1371/journal.pone.0266573.Peer-Reviewed Original ResearchConceptsScreening toolUniversal testingCommunity HIV-care providersCombination HIV prevention packageHIV-care providersHIV-positiveHIV prevention packageRapid HIV testingHIV test resultsRapid HIV test resultsHistory of hospital admissionIdentification of adolescentsPopART interventionUndiagnosed HIVHIV testingPrevention packageDoor-to-doorPoor healthHIV interventionsCommunity settingsConsented adolescentsHospital admissionSelf-reportSouth AfricaPopART
2021
Community-based health workers implementing universal access to HIV testing and treatment: lessons from South Africa and Zambia—HPTN 071 (PopART)
Viljoen L, Mainga T, Casper R, Mubekapi-Muzadaidzwa C, Wademan D, Bond V, Pliakas T, Bwalya C, Stangl A, Phiri M, Yang B, Shanaube K, Bock P, Fidler S, Hayes R, Ayles H, Hargreaves J, Hoddinott G, Seeley J, Donnell D, Floyd S, Mandla N, Bwalya J, Sabapathy K, Eshleman S, Macleod D, Moore A, Vermund S, Hauck K, Shanaube K. Community-based health workers implementing universal access to HIV testing and treatment: lessons from South Africa and Zambia—HPTN 071 (PopART). Health Policy And Planning 2021, 36: 881-890. PMID: 33963387, PMCID: PMC8227454, DOI: 10.1093/heapol/czab019.Peer-Reviewed Original ResearchConceptsCommunity-based health workersHIV testingHealth workersHIV prevention packageHPTN 071 (PopART) trialHIV epidemic controlPopulation health benefitsPopART interventionCHW interventionPrevention packageTreatment servicesIntervention staffTrial outcomesBaseline quantitative dataReferral servicesCHW retentionHealth benefitsIntervention packageProcess evaluationEpidemic controlGroup discussionsInterventionTrialsKey informant interviewsEmotional support
2014
HPTN 071 (PopART): Rationale and design of a cluster-randomised trial of the population impact of an HIV combination prevention intervention including universal testing and treatment – a study protocol for a cluster randomised trial
Hayes R, Ayles H, Beyers N, Sabapathy K, Floyd S, Shanaube K, Bock P, Griffith S, Moore A, Watson-Jones D, Fraser C, Vermund SH, Fidler S, The HPTN 071 (PopART) Study Team. HPTN 071 (PopART): Rationale and design of a cluster-randomised trial of the population impact of an HIV combination prevention intervention including universal testing and treatment – a study protocol for a cluster randomised trial. Trials 2014, 15: 57. PMID: 24524229, PMCID: PMC3929317, DOI: 10.1186/1745-6215-15-57.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAnti-HIV AgentsCircumcision, MaleClinical ProtocolsCost-Benefit AnalysisDrug Administration ScheduleFemaleHealth Care CostsHIV InfectionsHumansIncidenceMaleMass ScreeningPredictive Value of TestsPrevalenceResearch DesignSouth AfricaTime FactorsTreatment OutcomeYoung AdultZambiaConceptsImmediate antiretroviral treatmentAntiretroviral treatmentHIV incidenceHIV testingCombination HIV prevention packageHIV combination prevention interventionsHome-based HIV testingUniversal testingCombination prevention interventionsHIV prevention packageHPTN 071 (PopART) trialUniversal HIV testingHIV-negative menCluster-randomised trialCurrent national guidelinesStandard of careMedical male circumcisionPublic health problemThree-arm designPotential adverse effectsART initiationHPTN 071Testing HIVSecondary outcomesArm B