2019
Effect of Universal Testing and Treatment on HIV Incidence — HPTN 071 (PopART)
Hayes RJ, Donnell D, Floyd S, Mandla N, Bwalya J, Sabapathy K, Yang B, Phiri M, Schaap A, Eshleman SH, Piwowar-Manning E, Kosloff B, James A, Skalland T, Wilson E, Emel L, Macleod D, Dunbar R, Simwinga M, Makola N, Bond V, Hoddinott G, Moore A, Griffith S, Deshmane Sista N, Vermund SH, El-Sadr W, Burns DN, Hargreaves JR, Hauck K, Fraser C, Shanaube K, Bock P, Beyers N, Ayles H, Fidler S. Effect of Universal Testing and Treatment on HIV Incidence — HPTN 071 (PopART). New England Journal Of Medicine 2019, 381: 207-218. PMID: 31314965, PMCID: PMC6587177, DOI: 10.1056/nejmoa1814556.Peer-Reviewed Original ResearchConceptsHIV-positive participantsViral suppressionHIV infectionGroup BGroup AGroup CMonth 12Universal testingPrevention interventionsPopulation cohortHuman immunodeficiency virus (HIV) infectionHome-based HIV testingBaseline HIV prevalenceCombination prevention interventionsImmunodeficiency virus infectionHIV-positive adultsPopulation-level incidenceNew HIV infectionsAdjusted rate ratiosCommunity-randomized trialLack of effectHIV carePrevious trial resultsStandard careART adherence
2018
Partners-based HIV treatment for seroconcordant couples attending antenatal and postnatal care in rural Mozambique: A cluster randomized trial protocol
Audet CM, Graves E, Barreto E, De Schacht C, Gong W, Shepherd BE, Aboobacar A, Gonzalez-Calvo L, Alvim MF, Aliyu MH, Kipp AM, Jordan H, Amico KR, Diemer M, Ciaranello A, Dugdale C, Vermund SH, Van Rompaey S. Partners-based HIV treatment for seroconcordant couples attending antenatal and postnatal care in rural Mozambique: A cluster randomized trial protocol. Contemporary Clinical Trials 2018, 71: 63-69. PMID: 29879469, PMCID: PMC6067957, DOI: 10.1016/j.cct.2018.05.020.Peer-Reviewed Original ResearchConceptsChild transmissionSeroconcordant couplesMale partnersResource-limited rural settingsElimination of motherRoutine clinical dataUptake of servicesClinical trial designMale partner approvalAntiretroviral therapyHIV careAntenatal careRural MozambiqueHIV servicesPostnatal carePregnant womenHIV treatmentTrial protocolClinical dataHealth facilitiesTrial designHIVNewborn childrenPartner approvalEngagement interventions
2017
Differences in health-related quality of life between HIV-positive and HIV-negative people in Zambia and South Africa: a cross-sectional baseline survey of the HPTN 071 (PopART) trial
Thomas R, Burger R, Harper A, Kanema S, Mwenge L, Vanqa N, Bell-Mandla N, Smith P, Floyd S, Bock P, Ayles H, Beyers N, Donnell D, Fidler S, Hayes R, Hauck K, Team H, Hargreaves J, Watson-Jones D, Godfrey-Faussett P, Cori A, Pickles M, Mandla N, Yang B, James A, Vermaak R, Makola N, Hoddinott G, Naidoo V, Bond V, Simwinga M, Mwinga A, Kosloff B, Limbada M, Bwalya J, Ngulube C, Fraser C, Eshleman S, Agyei Y, Cummings V, Catalano D, Emel L, Bunts L, Noble H, Burns D, Kouda A, Sista N, Moore A, White R, Headen T, Miller E, Hinson K, Vermund S, Barnes M, Horn L, Mwango A, Baldwin M, Wolf S, Hughes E. Differences in health-related quality of life between HIV-positive and HIV-negative people in Zambia and South Africa: a cross-sectional baseline survey of the HPTN 071 (PopART) trial. The Lancet Global Health 2017, 5: e1133-e1141. PMID: 28964756, PMCID: PMC5640509, DOI: 10.1016/s2214-109x(17)30367-4.Peer-Reviewed Original ResearchConceptsHIV-negative peopleHIV-positive individualsHIV-negative individualsAntiretroviral therapyHealth-related qualityHIV careHRQoL scoresHIV statusHerpes simplex virus type-2 statusNational InstituteHPTN 071 (PopART) studyHPTN 071 (PopART) trialLaboratory-confirmed HIVType 2 statusCross-sectional baseline surveyLarge cross-sectional surveyRecreational drug useCross-sectional surveyPresident's Emergency PlanGeneral population sampleHRQoL informationBetter HRQoLHIV-negativeHIV progressionHRQoL dataHIV status disclosure, facility-based delivery and postpartum retention of mothers in a prevention clinical trial in rural Nigeria
Sarko KA, Blevins M, Ahonkhai AA, Audet CM, Moon TD, Gebi UI, Gana AM, Wester CW, Vermund SH, Aliyu MH. HIV status disclosure, facility-based delivery and postpartum retention of mothers in a prevention clinical trial in rural Nigeria. International Health 2017, 9: 243-251. PMID: 28810669, PMCID: PMC5881261, DOI: 10.1093/inthealth/ihx023.Peer-Reviewed Original ResearchConceptsHIV status disclosureFacility-based deliveryPostpartum retentionStatus disclosureHIV statusIntervention armWeeks postpartumChild HIV transmission (PMTCT) trialTrial intervention armPrevention of motherUnknown HIV statusPrevention clinical trialsMixed-effects logistic regressionEffects logistic regressionPMTCT continuumHIV careTreatment-naïveAntenatal carePregnant womenFacility deliveryMaternal ageObstetric servicesCare measuresClinical trialsHealth facilitiesAdapting an adherence support workers intervention: engaging traditional healers as adherence partners for persons enrolled in HIV care and treatment in rural Mozambique
Audet CM, Salato J, Vermund SH, Amico KR. Adapting an adherence support workers intervention: engaging traditional healers as adherence partners for persons enrolled in HIV care and treatment in rural Mozambique. Implementation Science 2017, 12: 50. PMID: 28407813, PMCID: PMC5390357, DOI: 10.1186/s13012-017-0582-z.Peer-Reviewed Original ResearchConceptsCommunity health workersAntiretroviral therapyWorker interventionTraditional healersHealth workersHealth systemAllopathic health systemEvidence-informed interventionsLow-literacy populationsHIV careHIV diagnosisRural MozambiquePatient adherenceHIV epidemicHealth facilitiesClinical careHealthcare providersHealth workforceHIVTraditional treatmentCommunity-based activitiesInterventionTraditional medicineCareSuccessful program implementationMobility and Clinic Switching Among Postpartum Women Considered Lost to HIV Care in South Africa
Clouse K, Vermund SH, Maskew M, Lurie MN, MacLeod W, Malete G, Carmona S, Sherman G, Fox MP. Mobility and Clinic Switching Among Postpartum Women Considered Lost to HIV Care in South Africa. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2017, 74: 383-389. PMID: 28225717, PMCID: PMC5324708, DOI: 10.1097/qai.0000000000001284.Peer-Reviewed Original ResearchConceptsHIV careNational Health Laboratory Service databaseLow CD4 cell countsNational Antiretroviral Therapy ProgramCD4 cell countObservational cohort studyAntiretroviral therapy programsAntiretroviral therapyCohort studyPostpartum womenPublic clinicsService databaseCell countTherapy programCareWomenLTFUClinicOne-thirdDaysPatientsPregnancyTherapyThe Continuum of HIV Care in the Urban United States: Black Men Who Have Sex With Men (MSM) Are Less Likely Than White MSM to Receive Antiretroviral Therapy
Vermund SH. The Continuum of HIV Care in the Urban United States: Black Men Who Have Sex With Men (MSM) Are Less Likely Than White MSM to Receive Antiretroviral Therapy. The Journal Of Infectious Diseases 2017, 216: 790-794. PMID: 28368523, PMCID: PMC5853891, DOI: 10.1093/infdis/jix009.Peer-Reviewed Original Research
2016
High HIV prevalence and the internet as a source of HIV-related service information at a community-based organization in Peru: a cross-sectional study of men who have sex with men
Passaro RC, Haley CA, Sanchez H, Vermund SH, Kipp AM. High HIV prevalence and the internet as a source of HIV-related service information at a community-based organization in Peru: a cross-sectional study of men who have sex with men. BMC Public Health 2016, 16: 871. PMID: 27557857, PMCID: PMC4997688, DOI: 10.1186/s12889-016-3561-4.Peer-Reviewed Original ResearchMeSH KeywordsAdultCommunity Health ServicesCross-Sectional StudiesHIV InfectionsHomosexuality, MaleHumansInformation Seeking BehaviorInformation ServicesInternetLogistic ModelsMaleMarketing of Health ServicesOdds RatioPatient Acceptance of Health CarePeer GroupPeruPrevalenceRisk-TakingSex WorkersSexual BehaviorSexual PartnersYoung AdultConceptsHIV prevalenceHIV servicesCross-sectional studyHIV careCommunity-based organizationsMethodsA cross-sectional studyMultivariable logistic regression modelSource of HIVHigh-risk personsSex workersHigh HIV prevalenceGeneral adult populationSex workers groupSexual risk behaviorsResource-limited settingsLogistic regression modelsHIV diagnosisWorker groupsHigh riskAdult populationInfected individualsPerson groupRisk behaviorsRisk profileMSMPatient and Provider Satisfaction With a Comprehensive Strategy to Improve Prevention of Mother-to-Child HIV Transmission Services in Rural Nigeria
Boehmer A, Audet CM, Blevins M, Gebi UI, Wester CW, Vermund SH, Aliyu MH. Patient and Provider Satisfaction With a Comprehensive Strategy to Improve Prevention of Mother-to-Child HIV Transmission Services in Rural Nigeria. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2016, 72: s117-s123. PMID: 27355498, PMCID: PMC5113240, DOI: 10.1097/qai.0000000000001058.Peer-Reviewed Original ResearchConceptsPrevention of motherProvider satisfactionPatient satisfactionWeeks postpartumControl armIntervention sitesChild HIV transmission servicesChild HIV transmission rateMother-infant careCD4 cell countHIV transmission ratesCluster-randomized trialTotal patient satisfactionAntiretroviral therapyHIV careChild transmissionPrescribed treatmentClinician satisfactionHealth personnelLower cadre workersCell countHealth problemsMale involvementProvider rolesProviders' abilityMeasuring Health Literacy Among Adults with HIV Infection in Mozambique: Development and Validation of the HIV Literacy Test
Tique JA, Howard LM, Gaveta S, Sidat M, Rothman RL, Vermund SH, Ciampa PJ. Measuring Health Literacy Among Adults with HIV Infection in Mozambique: Development and Validation of the HIV Literacy Test. AIDS And Behavior 2016, 21: 822-832. PMID: 26961538, PMCID: PMC5306223, DOI: 10.1007/s10461-016-1348-3.Peer-Reviewed Original ResearchConceptsLiteracy skillsParticipants' literacy skillsLiteracy-related tasksLiteracy testHIV careHigher literacy skillsLiteracy measuresHealth literacyInternal reliabilityConstruct validityRelationship of literacyHigher scoresSkillsHealth communicationConvenience sampleHypothetical modelAntiretroviral treatmentHIV infectionHIV outcomesDiverse settingsLiteracyAdultsCareHIVTaskBarriers and Facilitators of Linkage to and Engagement in HIV Care Among HIV-Positive Men Who Have Sex with Men in China: A Qualitative Study
Liu Y, Osborn CY, Qian HZ, Yin L, Xiao D, Ruan Y, Simoni JM, Zhang X, Shao Y, Vermund SH, Amico KR. Barriers and Facilitators of Linkage to and Engagement in HIV Care Among HIV-Positive Men Who Have Sex with Men in China: A Qualitative Study. AIDS Patient Care And STDs 2016, 30: 70-77. PMID: 26784360, PMCID: PMC4753635, DOI: 10.1089/apc.2015.0296.Peer-Reviewed Original ResearchMeSH KeywordsAdultChinaConfidentialityFearFocus GroupsHealth Knowledge, Attitudes, PracticeHealth ServicesHealth Services AccessibilityHIV InfectionsHomosexuality, MaleHumansInterviews as TopicMalePeer GroupPrejudicePrevalenceQualitative ResearchRisk-TakingSexual PartnersSocial StigmaSocioeconomic FactorsConceptsHIV-positive MSMFacilitators of linkageHIV careAntiretroviral therapyCurrent HIV preventionFree HIV careHIV-positive patientsHIV-positive menHIV care servicesHealth care workersFocus group discussionsContinuum of careHIV transmissionCare interventionsHIV preventionClinic timeCare workersQualitative studyCare servicesKey populationsPsychological burdenMSMCarePeer referralDisclosure concerns
2015
Predictors of antiretroviral therapy initiation: a cross-sectional study among Chinese HIV-infected men who have sex with men
Liu Y, Ruan Y, Vermund SH, Osborn CY, Wu P, Jia Y, Shao Y, Qian HZ. Predictors of antiretroviral therapy initiation: a cross-sectional study among Chinese HIV-infected men who have sex with men. BMC Infectious Diseases 2015, 15: 570. PMID: 26714889, PMCID: PMC4696158, DOI: 10.1186/s12879-015-1309-x.Peer-Reviewed Original ResearchConceptsCells/μLAntiretroviral therapy initiationART initiationHIV infectionCross-sectional studyTherapy initiationChinese MSMWorld Health Organization (WHO) clinical stage III/IVClinical stage III/IVStage III/IVNational HIV treatment guidelinesCD4 cell countHIV treatment guidelinesHIV viral suppressionLonger durationLogistic regression modelsChinese HIVEligible HIVCD4 countHIV careViral suppressionART eligibilityMedian durationTreatment guidelinesClinical symptomsQualitative Assessment of Barriers and Facilitators of Access to HIV Testing Among Men Who Have Sex with Men in China
Liu Y, Sun X, Qian HZ, Yin L, Yan Z, Wang L, Jiang S, Lu H, Ruan Y, Shao Y, Vermund SH, Amico KR. Qualitative Assessment of Barriers and Facilitators of Access to HIV Testing Among Men Who Have Sex with Men in China. AIDS Patient Care And STDs 2015, 29: 481-489. PMID: 26186029, PMCID: PMC4553375, DOI: 10.1089/apc.2015.0083.Peer-Reviewed Original ResearchConceptsHIV testingHIV prevention intervention effortsLimited HIV knowledgeHIV testing ratesHIV-positive groupHigh-risk subgroupsDiagnosis of HIVHigh-risk behaviorsFacilitators of accessPrevention intervention effortsHIV careHIV servicesHIV knowledgeRisk subgroupsClinic timeNosocomial infectionsChinese MSMUltimate preventionFocus groupsTesting ratesOnward transmissionPositive diagnosisRapid linkageHIVIntervention developmentPrevalence and risk factors of cervical squamous intraepithelial lesions among HIV-infected women in Dar es Salaam, Tanzania
Liu E, McCree R, Mtisi E, Fawzi WW, Aris E, Lema IA, Hertzmark E, Chalamilla G, Li N, Vermund SH, Spiegelman D. Prevalence and risk factors of cervical squamous intraepithelial lesions among HIV-infected women in Dar es Salaam, Tanzania. International Journal Of STD & AIDS 2015, 27: 219-225. PMID: 25957324, PMCID: PMC11340030, DOI: 10.1177/0956462415584466.Peer-Reviewed Original ResearchConceptsCervical squamous intraepithelial lesionsSquamous intraepithelial lesionsHIV disease stageCell countIntraepithelial lesionsDisease stageHigh-grade squamous intraepithelial lesionsAdvanced HIV disease stageCervical cancer prevention servicesLow CD4 cell countsCD4 cell countCancer prevention servicesCross-sectional studyResource-limited settingsCervical inflammationLow CD4Median CD4HIV careMedian ageCervical screeningPapanicolaou smearsRisk factorsTreatment clinicsPrevention servicesHIVSouthern Africa: the Highest Priority Region for HIV Prevention and Care Interventions
Vermund SH, Sheldon EK, Sidat M. Southern Africa: the Highest Priority Region for HIV Prevention and Care Interventions. Current HIV/AIDS Reports 2015, 12: 191-195. PMID: 25869940, PMCID: PMC4536916, DOI: 10.1007/s11904-015-0270-z.Peer-Reviewed Original ResearchConceptsHIV/AIDS reportBurden of HIVHigh HIV prevalenceHealth care workersGlobal HIV pandemicHIV/AIDSHIV careHIV prevalenceAIDS reportCare interventionsHIV preventionEpidemiological trendsHIV pandemicCare workersHealth servicesHealth workforcePutative causeMultiple factorsViral biologyCauseHIVPrevalenceAIDSCarePrevention
2014
Two-Year Death and Loss to Follow-Up Outcomes by Source of Referral to HIV Care for HIV-Infected Patients Initiating Antiretroviral Therapy in Rural Mozambique
Blevins M, José E, Bilhete FR, Vaz LM, Shepherd BE, Audet CM, Vermund SH, Moon TD. Two-Year Death and Loss to Follow-Up Outcomes by Source of Referral to HIV Care for HIV-Infected Patients Initiating Antiretroviral Therapy in Rural Mozambique. AIDS Research And Human Retroviruses 2014, 31: 198-207. PMID: 25381732, PMCID: PMC4532902, DOI: 10.1089/aid.2014.0007.Peer-Reviewed Original ResearchConceptsSource of referralCombination antiretroviral therapyRural Zambézia ProvinceReferral sitesAntiretroviral therapyAntenatal careGeneral outpatient clinicCumulative incidence estimatesAdditional unmeasured factorsCART initiationHIV careHazard ratioPatient characteristicsHIV testingMedian ageVoluntary counselingCox regressionOutpatient clinicKaplan-MeierPatient populationMedication pickupPatient outcomesInpatient careLTFUIncidence estimatesAntiretroviral Therapy Program Expansion in Zambézia Province, Mozambique: Geospatial Mapping of Community-Based and Health Facility Data for Integrated Health Planning
Moon TD, Ossemane EB, Green AF, Ndatimana E, José E, Buehler CP, Wester CW, Vermund SH, Olupona O. Antiretroviral Therapy Program Expansion in Zambézia Province, Mozambique: Geospatial Mapping of Community-Based and Health Facility Data for Integrated Health Planning. PLOS ONE 2014, 9: e109653. PMID: 25329169, PMCID: PMC4201452, DOI: 10.1371/journal.pone.0109653.Peer-Reviewed Original ResearchConceptsHIV populationZambézia ProvinceCommunity-based VCTCommunity-based voluntary counselingHIV testing resultsProgram demographic informationHIV seropositivity rateHealth facility dataProgram expansionHIV careVoluntary counselingSeropositivity rateTesting deliveryEvidence-based decisionsHealth planningTreatment monitoringGeospatial mappingDemographic informationHealth estimatesClinicFacility dataCommunity-BasedProgram planningCareVCTHIV Stigma as a Barrier to Retention in HIV Care at a General Hospital in Lima, Peru: A Case–Control Study
Valenzuela C, Ugarte-Gil C, Paz J, Echevarria J, Gotuzzo E, Vermund SH, Kipp AM. HIV Stigma as a Barrier to Retention in HIV Care at a General Hospital in Lima, Peru: A Case–Control Study. AIDS And Behavior 2014, 19: 235-245. PMID: 25269871, PMCID: PMC4344383, DOI: 10.1007/s10461-014-0908-7.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAnti-HIV AgentsCase-Control StudiesContinuity of Patient CareFemaleHealth Knowledge, Attitudes, PracticeHealth Services AccessibilityHIV InfectionsHospitals, GeneralHumansInterviews as TopicMaleMiddle AgedPeruPrejudiceSelf ConceptSocial StigmaStereotypingSurveys and QuestionnairesConceptsCase-control studyHIV careHIV stigmaDisclosure concernsMultivariable logistic regressionHIV Stigma ScaleNon-linear associationWarrants further explorationClinic visitsGeneral HospitalStigma domainsStigma scoresActive careStigma ScaleModest associationLogistic regressionCareAssociationStigmaFurther explorationHigh levelsPatientsHospitalChallenges in the Detection, Prevention, and Treatment of HIV-Associated Malignancies in Low- and Middle-Income Countries in Africa
Adebamowo CA, Casper C, Bhatia K, Mbulaiteye SM, Sasco AJ, Phipps W, Vermund SH, Krown SE. Challenges in the Detection, Prevention, and Treatment of HIV-Associated Malignancies in Low- and Middle-Income Countries in Africa. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2014, 67: s17-s26. PMID: 25117957, PMCID: PMC4392880, DOI: 10.1097/qai.0000000000000255.Peer-Reviewed Original ResearchConceptsMiddle-income countriesAntiretroviral therapy usageChronic HIV careHIV-Associated MalignanciesCombination antiretroviral therapyHIV/AIDSPresident's Emergency PlanLong-term careHealth care infrastructureHIV workforceAntiretroviral therapyHIV careMajor complicationsHIV statusTherapy usageCancer CenterCancer patientsHost genetic profileHigh-income countriesEarly diagnosisBiology of cancerHIVOptimal managementAIDS ReliefCancerMobile clinics for antiretroviral therapy in rural Mozambique
Moon TD, Jequicene T, Blevins M, José E, Lankford JR, Wester CW, Fuchs MC, Vermund SH. Mobile clinics for antiretroviral therapy in rural Mozambique. Bulletin Of The World Health Organization 2014, 92: 680-684. PMID: 25378759, PMCID: PMC4208568, DOI: 10.2471/blt.13.129478.Peer-Reviewed Original ResearchConceptsHIV careClinic strategyHealth care infrastructureAntiretroviral therapy programsHuman immunodeficiency virusUptake of servicesPresident's Emergency PlanLocal health systemsMonths of implementationAntiretroviral therapyImmunodeficiency virusPeripheral clinicsNew patientsMobile clinicsAdult populationART expansionClinicTherapy programAIDS ReliefHealth systemCareTreatmentRural MozambiqueRural regionsNational coverage