2017
Mobility and Clinic Switching Among Postpartum Women Considered Lost to HIV Care in South Africa
Clouse K, Vermund SH, Maskew M, Lurie MN, MacLeod W, Malete G, Carmona S, Sherman G, Fox MP. Mobility and Clinic Switching Among Postpartum Women Considered Lost to HIV Care in South Africa. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2017, 74: 383-389. PMID: 28225717, PMCID: PMC5324708, DOI: 10.1097/qai.0000000000001284.Peer-Reviewed Original ResearchConceptsHIV careNational Health Laboratory Service databaseLow CD4 cell countsNational Antiretroviral Therapy ProgramCD4 cell countObservational cohort studyAntiretroviral therapy programsAntiretroviral therapyCohort studyPostpartum womenPublic clinicsService databaseCell countTherapy programCareWomenLTFUClinicOne-thirdDaysPatientsPregnancyTherapy
2016
Patient and Provider Satisfaction With a Comprehensive Strategy to Improve Prevention of Mother-to-Child HIV Transmission Services in Rural Nigeria
Boehmer A, Audet CM, Blevins M, Gebi UI, Wester CW, Vermund SH, Aliyu MH. Patient and Provider Satisfaction With a Comprehensive Strategy to Improve Prevention of Mother-to-Child HIV Transmission Services in Rural Nigeria. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2016, 72: s117-s123. PMID: 27355498, PMCID: PMC5113240, DOI: 10.1097/qai.0000000000001058.Peer-Reviewed Original ResearchConceptsPrevention of motherProvider satisfactionPatient satisfactionWeeks postpartumControl armIntervention sitesChild HIV transmission servicesChild HIV transmission rateMother-infant careCD4 cell countHIV transmission ratesCluster-randomized trialTotal patient satisfactionAntiretroviral therapyHIV careChild transmissionPrescribed treatmentClinician satisfactionHealth personnelLower cadre workersCell countHealth problemsMale involvementProvider rolesProviders' abilityIntegrated prevention of mother-to-child HIV transmission services, antiretroviral therapy initiation, and maternal and infant retention in care in rural north-central Nigeria: a cluster-randomised controlled trial
Aliyu MH, Blevins M, Audet CM, Kalish M, Gebi UI, Onwujekwe O, Lindegren ML, Shepherd BE, Wester CW, Vermund SH. Integrated prevention of mother-to-child HIV transmission services, antiretroviral therapy initiation, and maternal and infant retention in care in rural north-central Nigeria: a cluster-randomised controlled trial. The Lancet HIV 2016, 3: e202-e211. PMID: 27126487, PMCID: PMC4852280, DOI: 10.1016/s2352-3018(16)00018-7.Peer-Reviewed Original ResearchMeSH KeywordsAcquired Immunodeficiency SyndromeAdolescentAdultAnti-HIV AgentsCD4 Lymphocyte CountDelivery of Health Care, IntegratedEarly Intervention, EducationalFamilyFemaleHIV InfectionsHumansInfantInfectious Disease Transmission, VerticalMaleMothersNevirapineNigeriaPregnancyPregnancy Complications, InfectiousPrenatal CareRural PopulationYoung AdultConceptsChild HIV transmissionAntiretroviral therapyStandard of careRural North-Central NigeriaWeeks post partumIntervention groupAntiretroviral prophylaxisEligible womenHIV statusHIV transmissionSecondary level health care facilitiesChild HIV transmission servicesClinical stage 1 diseasePost partumEunice Kennedy Shriver National InstituteMedian CD4 countPMTCT service deliveryAntiretroviral therapy initiationCD4 cell countPrevention of motherStage 1 diseaseUnknown HIV statusElimination of motherNorth Central NigeriaEarly infant diagnosis
2015
Predictors of antiretroviral therapy initiation: a cross-sectional study among Chinese HIV-infected men who have sex with men
Liu Y, Ruan Y, Vermund SH, Osborn CY, Wu P, Jia Y, Shao Y, Qian HZ. Predictors of antiretroviral therapy initiation: a cross-sectional study among Chinese HIV-infected men who have sex with men. BMC Infectious Diseases 2015, 15: 570. PMID: 26714889, PMCID: PMC4696158, DOI: 10.1186/s12879-015-1309-x.Peer-Reviewed Original ResearchConceptsCells/μLAntiretroviral therapy initiationART initiationHIV infectionCross-sectional studyTherapy initiationChinese MSMWorld Health Organization (WHO) clinical stage III/IVClinical stage III/IVStage III/IVNational HIV treatment guidelinesCD4 cell countHIV treatment guidelinesHIV viral suppressionLonger durationLogistic regression modelsChinese HIVEligible HIVCD4 countHIV careViral suppressionART eligibilityMedian durationTreatment guidelinesClinical symptomsPrevalence and risk factors of cervical squamous intraepithelial lesions among HIV-infected women in Dar es Salaam, Tanzania
Liu E, McCree R, Mtisi E, Fawzi WW, Aris E, Lema IA, Hertzmark E, Chalamilla G, Li N, Vermund SH, Spiegelman D. Prevalence and risk factors of cervical squamous intraepithelial lesions among HIV-infected women in Dar es Salaam, Tanzania. International Journal Of STD & AIDS 2015, 27: 219-225. PMID: 25957324, PMCID: PMC11340030, DOI: 10.1177/0956462415584466.Peer-Reviewed Original ResearchConceptsCervical squamous intraepithelial lesionsSquamous intraepithelial lesionsHIV disease stageCell countIntraepithelial lesionsDisease stageHigh-grade squamous intraepithelial lesionsAdvanced HIV disease stageCervical cancer prevention servicesLow CD4 cell countsCD4 cell countCancer prevention servicesCross-sectional studyResource-limited settingsCervical inflammationLow CD4Median CD4HIV careMedian ageCervical screeningPapanicolaou smearsRisk factorsTreatment clinicsPrevention servicesHIV
2014
Symptomatic HIV-Positive Persons in Rural Mozambique Who First Consult a Traditional Healer Have Delays in HIV Testing
Audet CM, Blevins M, Rosenberg C, Farnsworth S, Salato J, Fernandez J, Vermund SH. Symptomatic HIV-Positive Persons in Rural Mozambique Who First Consult a Traditional Healer Have Delays in HIV Testing. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2014, 66: e80-e86. PMID: 24815853, PMCID: PMC4077983, DOI: 10.1097/qai.0000000000000194.Peer-Reviewed Original ResearchConceptsHIV testingTraditional healersHealth facility visitsLow CD4 cellsCD4 cell countHIV-seropositive personsHIV-positive personsCross-sectional studyPrevious health careLocal health facilitiesHIV/AIDSTime of HIVAntiretroviral therapyTherapy delayCD4 cellsHIV diagnosisMedian timeSicker patientsInitial careTime of entrySymptomatic individualsFacility visitsRelevant symptomsEarly diagnosisHealth facilities
2013
Impact of HIV drug resistance on virologic and immunologic failure and mortality in a cohort of patients on antiretroviral therapy in China
Liao L, Xing H, Su B, Wang Z, Ruan Y, Wang X, Liu Z, Lu Y, Yang S, Zhao Q, Vermund SH, Chen RY, Shao Y. Impact of HIV drug resistance on virologic and immunologic failure and mortality in a cohort of patients on antiretroviral therapy in China. AIDS 2013, 27: 1815-1824. PMID: 23803794, PMCID: PMC3694318, DOI: 10.1097/qad.0b013e3283611931.Peer-Reviewed Original ResearchConceptsCombination antiretroviral therapyHIV drug resistanceImmunologic failureHigh mortalityVirologic failureAntiretroviral therapyEmergence of HIVDRBaseline CD4 cell countDrug resistanceCD4 cell countCohort of patientsSecond-line drugsEnd of studyProportional hazards modelRural Chinese countiesHIVDR mutationsMedian timePatient adherenceKaplan-MeierChinese patientsRisk factorsHazards modelPatientsCell countMortality
2012
Prevention, Detection, and Treatment of Coinfections: A Priority in Human Immunodeficiency Virus–Infected Persons to Reduce Viral Load and Consequent Disease Progression and Transmission : Comment on “Effect of Early Syphilis Infection on Plasma Viral Load and CD4 Cell Count in Human Immunodeficiency Virus–Infected Men”
Vermund SH. Prevention, Detection, and Treatment of Coinfections: A Priority in Human Immunodeficiency Virus–Infected Persons to Reduce Viral Load and Consequent Disease Progression and Transmission : Comment on “Effect of Early Syphilis Infection on Plasma Viral Load and CD4 Cell Count in Human Immunodeficiency Virus–Infected Men”. JAMA Internal Medicine 2012, 172: 1243-1244. PMID: 22824925, DOI: 10.1001/archinternmed.2012.3770.Peer-Reviewed Original Research
2009
Clinical and ultrasonographic features of abdominal tuberculosis in HIV positive adults in Zambia
Sinkala E, Gray S, Zulu I, Mudenda V, Zimba L, Vermund SH, Drobniewski F, Kelly P. Clinical and ultrasonographic features of abdominal tuberculosis in HIV positive adults in Zambia. BMC Infectious Diseases 2009, 9: 44. PMID: 19374757, PMCID: PMC2678139, DOI: 10.1186/1471-2334-9-44.Peer-Reviewed Original ResearchConceptsAbdominal tuberculosisClinical featuresWeight lossPara-aortic lymphadenopathyProbable abdominal tuberculosisCD4 cell countHIV-seropositive patientsHIV-positive adultsUniversity Teaching HospitalCells/μL.Cultures of biopsiesCommon ultrasound findingsHealth care facilitiesAbdominal tendernessSeropositive patientsAbdominal lymphadenopathyCD4 cellsHIV infectionMedical inpatientsAbdominal pathologyClinical manifestationsPersistent tendernessUltrasound findingsClinical algorithmUltrasonographic features
2000
Prevalence of and Risks for Cervical Human Papillomavirus Infection and Squamous Intraepithelial Lesions in Adolescent Girls: Impact of Infection With Human Immunodeficiency Virus
Moscicki AB, Ellenberg JH, Vermund SH, Holland CA, Darragh T, Crowley-Nowick PA, Levin L, Wilson CM. Prevalence of and Risks for Cervical Human Papillomavirus Infection and Squamous Intraepithelial Lesions in Adolescent Girls: Impact of Infection With Human Immunodeficiency Virus. JAMA Pediatrics 2000, 154: 127-134. PMID: 10665598, DOI: 10.1001/archpedi.154.2.127.Peer-Reviewed Original ResearchConceptsSquamous intraepithelial lesionsHPV infectionHuman papillomavirus infectionIntraepithelial lesionsPapillomavirus infectionHIV infectionHIV statusCervical human papillomavirus infectionLow-risk HPV typesCourse of HIVNormal cytologic findingsCD4 cell countCervical HPV infectionT-cell countsT-cell immunosuppressionHuman immunodeficiency virusHigh-risk typesAdolescent girlsSexual risk behaviorsImpact of infectionCD4 immunosuppressionBaseline visitHPV typesRisky sexual behaviorViral load
1999
Peripheral blood mononuclear cell markers in antiretroviral therapy-naive HIV-infected and high risk seronegative adolescents
Douglas S, Rudy B, Muenz L, Moscicki A, Wilson C, Holland C, Crowley-Nowick P, Vermund S. Peripheral blood mononuclear cell markers in antiretroviral therapy-naive HIV-infected and high risk seronegative adolescents. AIDS 1999, 13: 1629-1635. PMID: 10509563, DOI: 10.1097/00002030-199909100-00005.Peer-Reviewed Original ResearchConceptsAdolescent Medicine HIV/AIDS Research NetworkHIV-negative adolescentsHIV-negative femalesHIV-positive femalesHIV-positive adolescentsAntiretroviral therapyHIV infectionHealthy adolescentsAntiretroviral therapy-naive HIVTotal CD4 cell countsThree-color flow cytometryMononuclear cell markersNaive CD8 cellsTherapy-naive HIVCD4 cell countHIV-negative subjectsHIV-positive malesAIDS Research NetworkHigh-risk HIVCD8 memory cellsNatural killer cellsTotal leukocyte countREACH cohortSeronegative adolescentsCD8 cells