1981
Association between human tumor colony-forming assay results and response of an individual patient's tumor to chemotherapy
Von Hoff D, Casper J, Bradley E, Sandbach J, Jones D, Makuch R. Association between human tumor colony-forming assay results and response of an individual patient's tumor to chemotherapy. The American Journal Of Medicine 1981, 70: 1027-1032. PMID: 7234870, DOI: 10.1016/0002-9343(81)90859-7.Peer-Reviewed Original ResearchMeSH KeywordsAntineoplastic AgentsColony-Forming Units AssayFalse Negative ReactionsFalse Positive ReactionsHumansIn Vitro TechniquesNeoplasmsRetrospective StudiesConceptsIndividual patient's tumorPatient tumorsHuman tumorsGeneral oncology patientsParticular patient's tumorSeparate histologic typesProspective clinical trialsDrug sensitivity assaysColony-forming assaysHistologic typeOncology patientsClinical trialsPatient responsePatientsRetrospective mannerTumorsAntineoplastic agentsFluid specimenEnough cellsVivo resultsSensitivity assaysDrugsAssaysAssociationChemotherapy
1980
Direct cloning of human neuroblastoma cells in soft agar culture.
Von Hoff D, Casper J, Bradley E, Trent J, Hodach A, Reichert C, Makuch R, Altman A. Direct cloning of human neuroblastoma cells in soft agar culture. Cancer Research 1980, 40: 3591-7. PMID: 7002289.Peer-Reviewed Original ResearchConceptsSoft agar systemNeuroblastoma cellsBone marrowPositive bone marrowHuman neuroblastoma cellsBasic science studiesAgar systemNumber of coloniesMarrow examinationStem cell assayClinical courseLymph nodesPoor prognosisSoft agar cultureTumor responseCatecholamine secretionHistological statusMarrow samplesTumor relapseSoft agar techniquePatientsSolid tumorsPathology studiesCulture resultsNegative specimens