1988
Statistical Methods for the Analysis of HIV-1 Core Polypeptide Antigen Data in Clinical Studies
Makuch R, Parks W. Statistical Methods for the Analysis of HIV-1 Core Polypeptide Antigen Data in Clinical Studies. AIDS Research And Human Retroviruses 1988, 4: 305-316. PMID: 3061416, DOI: 10.1089/aid.1988.4.305.Peer-Reviewed Original ResearchConceptsPlacebo-treated patientsInitiation of therapyPlacebo-controlled studyHIV-1 antigensDemonstrated clinical efficacyHIV-1 coreAntiretroviral effectClinical efficacyAIDS patientsAntiretroviral activityClinical studiesLymphocyte culturesVirus expressionSerum dataAntigen dataPatientsSurvival analysis methodsLaboratory dataAZTGroup differencesMost laboratory dataCulture dataStatistical methodsSignificant declineSerum
1984
Elevated serum creatine kinase BB levels in patients with small cell lung cancer.
Carney D, Zweig M, Ihde D, Cohen M, Makuch R, Gazdar A. Elevated serum creatine kinase BB levels in patients with small cell lung cancer. Cancer Research 1984, 44: 5399-403. PMID: 6091876.Peer-Reviewed Original ResearchConceptsSmall cell lung cancerSerum CK-BBSerum CK-BB levelsCK-BB levelsCell lung cancerMetastatic sitesLung cancerCK-BBCreatine kinase BB levelsExtensive-stage diseaseSCLC cell linesClinical tumor specimensLimited diseaseClinical responseExtensive diseaseMetastatic diseaseUntreated patientsPretreatment stagingTumor disseminationTumor specimensPatientsBB isoenzymeBb levelsSignificant associationCreatine kinase
1981
Growth of lung cancer colonies from bronchoscopy washings
Von Hoff D, Weisenthal L, Ihde D, Mathews M, Layard M, Makuch R. Growth of lung cancer colonies from bronchoscopy washings. Cancer 1981, 48: 400-403. PMID: 7016303, DOI: 10.1002/1097-0142(19810715)48:2<400::aid-cncr2820480229>3.0.co;2-j.Peer-Reviewed Original Research
1980
Direct cloning of human neuroblastoma cells in soft agar culture.
Von Hoff D, Casper J, Bradley E, Trent J, Hodach A, Reichert C, Makuch R, Altman A. Direct cloning of human neuroblastoma cells in soft agar culture. Cancer Research 1980, 40: 3591-7. PMID: 7002289.Peer-Reviewed Original ResearchConceptsSoft agar systemNeuroblastoma cellsBone marrowPositive bone marrowHuman neuroblastoma cellsBasic science studiesAgar systemNumber of coloniesMarrow examinationStem cell assayClinical courseLymph nodesPoor prognosisSoft agar cultureTumor responseCatecholamine secretionHistological statusMarrow samplesTumor relapseSoft agar techniquePatientsSolid tumorsPathology studiesCulture resultsNegative specimens