2010
Preterm birth results in alterations in neural connectivity at age 16 years
Mullen KM, Vohr BR, Katz KH, Schneider KC, Lacadie C, Hampson M, Makuch RW, Reiss AL, Constable RT, Ment LR. Preterm birth results in alterations in neural connectivity at age 16 years. NeuroImage 2010, 54: 2563-2570. PMID: 21073965, PMCID: PMC3020252, DOI: 10.1016/j.neuroimage.2010.11.019.Peer-Reviewed Original ResearchConceptsDiffusion tensor imagingAge 16 yearsPT subjectsBrain injuryLow birth weight preterm childrenTerm controlsUncinate fasciculusBilateral external capsuleFA valuesWeight preterm childrenNeonatal brain injuryLower fractional anisotropy valuesYears of ageBilateral uncinate fasciculusFractional anisotropy valuesRight uncinate fasciculusRight arcuate fasciculusWhite matter disorganizationAlternative neural pathwaysPreterm birthExternal capsuleInferior frontal gyrusPreterm childrenCorpus callosumHigh risk
2009
GABAA‐benzodiazepine receptor availability in smokers and nonsmokers: Relationship to subsyndromal anxiety and depression
Esterlis I, Cosgrove KP, Batis JC, Bois F, Kloczynski TA, Stiklus SM, Perry E, Tamagnan GD, Seibyl JP, Makuch R, Krishnan‐Sarin S, O'Malley S, Staley JK. GABAA‐benzodiazepine receptor availability in smokers and nonsmokers: Relationship to subsyndromal anxiety and depression. Synapse 2009, 63: 1089-1099. PMID: 19642218, PMCID: PMC2778224, DOI: 10.1002/syn.20688.Peer-Reviewed Original ResearchConceptsSpielberger State-Trait Anxiety IndexState-Trait Anxiety IndexDepressive symptomsSubsyndromal anxietyAnxiety symptomsPain toleranceReceptor availabilityAbstinent tobacco smokersSex-matched nonsmokersSingle photon emissionPain symptomsHealthy ageSmoking statusTobacco smokersSubsyndromal depressionAbstinent smokersVulnerable smokersCold pressor taskNonsmokersGamma-aminobutyricEpidemiology ScaleSmokersAcute abstinenceBrain areasSymptomsAlterations in neural connectivity in preterm children at school age
Gozzo Y, Vohr B, Lacadie C, Hampson M, Katz KH, Maller-Kesselman J, Schneider KC, Peterson BS, Rajeevan N, Makuch RW, Constable RT, Ment LR. Alterations in neural connectivity in preterm children at school age. NeuroImage 2009, 48: 458-463. PMID: 19560547, PMCID: PMC2775072, DOI: 10.1016/j.neuroimage.2009.06.046.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingLanguage tasksWernicke's areaLanguage processingPeabody Individual Achievement TestRight inferior frontal gyrusPT childrenAuditory language functionsAuditory language taskCortical language regionsSchool ageInferior frontal gyrusReading comprehension testWechsler Intelligence ScalePeabody Picture VocabularyInferior parietal lobulePT subjectsSchool-aged childrenChildren-IIIComprehension testFrontal gyrusIntelligence ScalePicture VocabularyWISC-IIILanguage regions
2000
Regional Brain Volume Abnormalities and Long-term Cognitive Outcome in Preterm Infants
Peterson B, Vohr B, Staib L, Cannistraci C, Dolberg A, Schneider K, Katz K, Westerveld M, Sparrow S, Anderson A, Duncan C, Makuch R, Gore J, Ment L. Regional Brain Volume Abnormalities and Long-term Cognitive Outcome in Preterm Infants. JAMA 2000, 284: 1939-1947. PMID: 11035890, DOI: 10.1001/jama.284.15.1939.Peer-Reviewed Original ResearchConceptsRegional brain volumesLong-term cognitive outcomesPreterm childrenPreterm infantsBrain volumeBasal gangliaCorpus callosumCognitive outcomesRegional brain volume abnormalitiesTerm control childrenCase-control studyBrain volume abnormalitiesPoor cognitive outcomesRegional cortical volumesStructural magnetic resonanceMidtemporal cortexPreterm birthPremature birthTemporal hornPerinatal variablesSubgenual cortexUniversity Medical SchoolCortical volumeHigh prevalenceLongitudinal follow
1996
Variations in the natural history and survival of patients with supratentorial low-grade astrocytomas.
Piepmeier J, Susan Christopher R, Spencer D, Byrne T, Kim J, Knisel J, Lacy J, Tsukerman L, Makuch R. Variations in the natural history and survival of patients with supratentorial low-grade astrocytomas. Neurosurgery 1996, 38: 872-8; discussion 878-9. PMID: 8727811, DOI: 10.1097/00006123-199605000-00002.Peer-Reviewed Original ResearchConceptsLow-grade astrocytomasGross total resectionChronic epilepsySupratentorial low-grade astrocytomasNatural historyGross total tumor resectionImmediate postoperative radiotherapyExtent of surgerySurvival of patientsTen-year survivalPopulation of patientsUse of radiotherapyRisk of recurrenceHigh-grade lesionsLength of survivalMore malignant tumorsTypes of symptomsAggressive surgeryPostoperative radiotherapyPreoperative symptomsConsecutive patientsBetter prognosisTumor recurrenceTumor resectionMalignant tumors
1985
Patients with small-cell lung cancer treated with combination chemotherapy with or without irradiation. Data on potential cures, chronic toxicities, and late relapses after a five- to eleven-year follow-up.
Johnson B, Ihde D, Bunn P, Becker B, Walsh T, Weinstein Z, Matthews M, Whang-Peng J, Makuch R, Johnston-Early A. Patients with small-cell lung cancer treated with combination chemotherapy with or without irradiation. Data on potential cures, chronic toxicities, and late relapses after a five- to eleven-year follow-up. Annals Of Internal Medicine 1985, 103: 430-8. PMID: 2992337, DOI: 10.7326/0003-4819-103-3-430.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAntineoplastic Combined Chemotherapy ProtocolsBrainCarcinoma, Small CellCombined Modality TherapyFemaleFollow-Up StudiesHematologic DiseasesHumansLung NeoplasmsMaleMemory DisordersMiddle AgedNeoplasm Recurrence, LocalNervous System DiseasesRadiotherapyRespiratory Function TestsConceptsSmall cell lung cancerLung cancerCombination chemotherapyEvidence of cancerCancer-free survivalCell lung cancerCranial irradiationAggressive therapyLate toxicityUnrelated causesLate relapseTherapeutic trialsCancer 5PatientsPotential cureThirty-monthCancerChemotherapyRelapseCureChronic toxicityMonthsSurvivalEleven yearsToxicity
1982
Carcinomatous Leptomeningitis in Small Cell Lung Cancer
ROSEN S, AISNER J, MAKUCH R, MATTHEWS M, IHDE D, WHITACRE M, GLATSTEIN E, WIERNIK P, LICHTER A, BUNN P. Carcinomatous Leptomeningitis in Small Cell Lung Cancer. Medicine 1982, 61: 45. PMID: 6276648, DOI: 10.1097/00005792-198201000-00005.Peer-Reviewed Original ResearchConceptsClinical courseSystemic diseaseSpinal cordUnivariate log-rank analysisSmall cell lung cancerProgressive systemic diseaseLog-rank analysisPatient's clinical courseSpinal cord lesionsCell lung cancerVirchow-Robin spacesLife-table analysisCNS metastasesComplete respondersExtensive diseaseIntrathecal chemotherapyLiver metastasesMedian survivalSystemic therapyComplete responseCord lesionsIntracerebral metastasesAutopsy featuresDiffuse involvementSole manifestation