2024
Short-Term Exposure to Fine Particulate Matter and Nitrogen Dioxide and Mortality in 4 Countries
Ma Y, Nobile F, Marb A, Dubrow R, Stafoggia M, Breitner S, Kinney P, Chen K. Short-Term Exposure to Fine Particulate Matter and Nitrogen Dioxide and Mortality in 4 Countries. JAMA Network Open 2024, 7: e2354607. PMID: 38427355, PMCID: PMC10907920, DOI: 10.1001/jamanetworkopen.2023.54607.Peer-Reviewed Original ResearchConceptsShort-term exposure to air pollutionExposure to air pollutionFine particulate matterCross-sectional studyAir pollutionFixed-effects modelParticulate matterShort-term exposure to PM2.5Short-term exposure to fine particulate matterNO2 concentrationsExposure to fine particulate matterMortality rateNitrogen dioxideSignificant effect modificationDaily PM2.5 concentrationsTime-varying confoundersExposure to PM2.5Health outcomesEstimate associationsMortality dataEffect modificationPM2.5 concentrationsMain OutcomesDay-to-dayCentral-southern Italy
2023
Floods and Diarrhea Risk in Young Children in Low- and Middle-Income Countries
Wang P, Asare E, Pitzer V, Dubrow R, Chen K. Floods and Diarrhea Risk in Young Children in Low- and Middle-Income Countries. JAMA Pediatrics 2023, 177: 1206-1214. PMID: 37782513, PMCID: PMC10546297, DOI: 10.1001/jamapediatrics.2023.3964.Peer-Reviewed Original ResearchConceptsMiddle-income countriesDiarrhea riskOdds ratioMAIN OUTCOMEMixed-effects logistic regression modelRisk of diarrheaCross-sectional studyHigher odds ratioPrevalence of diarrheaLogistic regression modelsHealth survey programUnexposed childrenEffect modificationChild healthDiarrhea prevalenceSurvey clustersSignificant associationHygiene practicesFourth weekWeeksStrong associationRandom interceptYoung childrenChildrenDiarrheaTemperature variability and birthweight: Epidemiological evidence from Africa
Wang P, O'Donnell K, Warren J, Dubrow R, Chen K. Temperature variability and birthweight: Epidemiological evidence from Africa. Environment International 2023, 173: 107792. PMID: 36841185, DOI: 10.1016/j.envint.2023.107792.Peer-Reviewed Original Research
2020
Medical, nursing, and physician assistant student knowledge and attitudes toward climate change, pollution, and resource conservation in health care
Ryan EC, Dubrow R, Sherman JD. Medical, nursing, and physician assistant student knowledge and attitudes toward climate change, pollution, and resource conservation in health care. BMC Medical Education 2020, 20: 200. PMID: 32576175, PMCID: PMC7310528, DOI: 10.1186/s12909-020-02099-0.Peer-Reviewed Original ResearchConceptsPhysician assistant students' knowledgeExact testSignificant public health burdenPhysician assistant studentsPublic health burdenFisher's exact testHealth care sectorAssistant studentsDisease burdenCare sectorHealth burdenClinical practiceResponse ratePhysician assistantsPatient careClinical settingLack of timeHealth professional studentsLogistic regressionLack of educationHealth careHealth care materialsNursingDescriptive statisticsCareProjections of Ambient Temperature- and Air Pollution-Related Mortality Burden Under Combined Climate Change and Population Aging Scenarios: a Review
Chen K, Vicedo-Cabrera AM, Dubrow R. Projections of Ambient Temperature- and Air Pollution-Related Mortality Burden Under Combined Climate Change and Population Aging Scenarios: a Review. Current Environmental Health Reports 2020, 7: 243-255. PMID: 32542573, DOI: 10.1007/s40572-020-00281-6.Peer-Reviewed Original ResearchConceptsMortality burdenOlder adultsAge-stratified analysisAir pollution exposureNon-optimal ambient temperaturesVulnerable older adultsAge-specific population projectionsAge-specific relationshipsFuture population vulnerabilityPollution exposureRecent FindingsWeRecent evidenceBurdenHealth impactsAir pollutionMortalityTemperature-related mortality burdenFuture studiesAdultsLess reductionPopulationStrong evidence
2016
Risk of End-Stage Liver Disease in HIV-Viral Hepatitis Coinfected Persons in North America From the Early to Modern Antiretroviral Therapy Eras
Klein MB, Althoff KN, Jing Y, Lau B, Kitahata M, Re V, Kirk GD, Hull M, Kim HN, Sebastiani G, Moodie EE, Silverberg MJ, Sterling TR, Thorne JE, Cescon A, Napravnik S, Eron J, Gill MJ, Justice A, Peters MG, Goedert JJ, Mayor A, Thio CL, Cachay ER, Moore R, Research and Design of IeDEA F, Kirk G, Benson C, Bosch R, Boswell S, Mayer K, Grasso C, Hogg R, Harrigan P, Montaner J, Cescon A, Samji H, Brooks J, Buchacz K, Gebo K, Moore R, Moore R, Rodriguez B, Horberg M, Silverberg M, Thorne J, Goedert J, Jacobsonc L, D'Souza G, Klein M, Rourke S, Burchell A, Rachlis A, Hunter-Mellado R, Mayor A, Gill M, Deeks S, Martin J, Patel P, Brooks J, Saag M, Mugavero M, Willig J, Eron J, Napravnik S, Kitahata M, Crane H, Kim H, Drozd D, Sterling T, Haas D, Bebawy S, Turner M, Justice A, Dubrow R, Fiellin D, Gange S, Anastos K, Moore R, Saag M, Gange S, Kitahata M, Althoff K, McKaig R, Justice A, Freeman A, Moore R, Freeman A, Lent C, Kitahata M, Van Rompaey S, Crane H, Drozd D, Morton L, McReynolds J, Lober W, Gange S, Althoff K, Abraham A, Lau B, Zhang J, Jing J, Golub E, Modur S, Wong C, Hogan B, Tong W, Liu B. Risk of End-Stage Liver Disease in HIV-Viral Hepatitis Coinfected Persons in North America From the Early to Modern Antiretroviral Therapy Eras. Clinical Infectious Diseases 2016, 63: 1160-1167. PMID: 27506682, PMCID: PMC5064164, DOI: 10.1093/cid/ciw531.Peer-Reviewed Original ResearchConceptsEnd-stage liver diseaseUse of antiretroviralsESLD riskAntiretroviral therapyLiver diseaseNorth American AIDS Cohort CollaborationTime-updated CD4 cell countModern antiretroviral therapy (ART) eraAntiretroviral therapy eraTenofovir-based regimensCD4 cell countModern antiretroviral therapyHuman immunodeficiency virusIncidence rate ratiosRate ratioCohort CollaborationCoinfected PersonsTherapy eraHCV therapyHIV RNAHepatitis BHepatitis statusImmunodeficiency virusC virusAntiretroviral era
2007
Sex, condoms, gender roles, and HIV transmission knowledge among adolescents in León, Nicaragua: Implications for HIV prevention
Manji A, Peña R, Dubrow R. Sex, condoms, gender roles, and HIV transmission knowledge among adolescents in León, Nicaragua: Implications for HIV prevention. AIDS Care 2007, 19: 989-995. PMID: 17851995, DOI: 10.1080/09540120701244935.Peer-Reviewed Original ResearchConceptsHIV/AIDS-related knowledgePrevention interventionsPopulation-based cross-sectional surveyConcentrated HIV epidemicHIV prevention interventionsTransmission of HIVInconsistent condom useHIV transmission knowledgeHomosexuality-related stigmaHIV/AIDS stigmaCross-sectional surveyHIV infectionHIV epidemicTransmission knowledgeHIV preventionHealth facilitiesPeer-reviewed studiesCondom useAIDS stigmaMultivariate modelMost adolescentsSignificant correlatesSexual behaviorSexAdolescents
2006
Unprotected intercourse for extra money among commercial sex workers in Kinshasa, Democratic Republic of Congo
Ntumbanzondo M, Dubrow R, Niccolai L, Mwandagalirwa K, Merson M. Unprotected intercourse for extra money among commercial sex workers in Kinshasa, Democratic Republic of Congo. AIDS Care 2006, 18: 777-785. PMID: 16971288, DOI: 10.1080/09540120500412824.Peer-Reviewed Original Research
2001
Family history of cancer and risk of esophageal and gastric cancers in the United States
Dhillon P, Farrow D, Vaughan T, Chow W, Risch H, Gammon M, Mayne S, Stanford J, Schoenberg J, Ahsan H, Dubrow R, West A, Rotterdam H, Blot W, Fraumeni J. Family history of cancer and risk of esophageal and gastric cancers in the United States. International Journal Of Cancer 2001, 93: 148-152. PMID: 11391635, DOI: 10.1002/ijc.1294.Peer-Reviewed Original ResearchConceptsNon-cardia gastric adenocarcinomaFamily historyGastric cancerEsophageal cancerGastric adenocarcinomaEsophageal adenocarcinomaEsophageal squamous cell cancerNon-cardia gastric cancerEsophageal squamous cell carcinomaSquamous cell cancerRisk of esophagealSquamous cell carcinomaCase-control studyGastric cardia adenocarcinomaHigh incidence areaGastric cardiaIncreased riskCell carcinomaDigestive cancersRisk factorsStomach cancerProstate cancerBreast cancerGastric tumorsCardia adenocarcinoma
2000
Gastroesophageal reflux disease, use of H2 receptor antagonists, and risk of esophageal and gastric cancer
Farrow D, Vaughan T, Sweeney C, Gammon M, Chow W, Risch H, Stanford J, Hansten P, Mayne S, Schoenberg J, Rotterdam H, Ahsan H, West A, Dubrow R, Fraumeni J, Blot W. Gastroesophageal reflux disease, use of H2 receptor antagonists, and risk of esophageal and gastric cancer. Cancer Causes & Control 2000, 11: 231-238. PMID: 10782657, DOI: 10.1023/a:1008913828105.Peer-Reviewed Original ResearchConceptsGastroesophageal reflux diseaseNon-cardia gastric adenocarcinomaEsophageal adenocarcinomaGERD symptomsReflux diseaseH2 blockersGastric adenocarcinomaGastric cancerLarge population-based case-control studyPopulation-based case-control studyPopulation-based tumor registryEsophageal squamous cell carcinomaPerson structured interviewRisk of esophagealSquamous cell carcinomaEsophageal adenocarcinoma riskH2-receptor antagonistsCase-control studyGastric cardia adenocarcinomaRandom digit dialingLong-term usersTumor RegistryAdenocarcinoma riskDaily symptomsCell carcinomaOxychlordane and trans-nonachlor in breast adipose tissue and risk of female breast cancer.
Zheng T, Holford T, Tessari J, Mayne S, Zahm S, Owens P, Zhang B, Ward B, Carter D, Zhang Y, Zhang W, Dubrow R, Boyle P. Oxychlordane and trans-nonachlor in breast adipose tissue and risk of female breast cancer. Journal Of Cancer Epidemiology And Prevention 2000, 5: 153-60. PMID: 11051111.Peer-Reviewed Original ResearchConceptsAdipose tissue levelsBreast cancer riskFemale breast cancerBreast adipose tissueBreast cancerRisk factorsOdds ratioAdipose tissueBenign breast disease controlsFemale breast cancer riskPrimary breast cancer patientsCovariate-adjusted odds ratioEnvironmental exposuresProgesterone receptor statusBreast cancer patientsRecent epidemiological studiesMenopausal statusReceptor statusHighest quartileEpidemiological studiesCancerMajor metaboliteRiskStructured questionnaireOverall significant impact
1999
DDE and DDT in Breast Adipose Tissue and Risk of Female Breast Cancer
Zheng T, Holford T, Mayne S, Ward B, Carter D, Ownes P, Dubrow R, Zahm S, Boyle P, Archibeque S, Tessari J. DDE and DDT in Breast Adipose Tissue and Risk of Female Breast Cancer. American Journal Of Epidemiology 1999, 150: 453-458. PMID: 10472944, DOI: 10.1093/oxfordjournals.aje.a010033.Peer-Reviewed Original ResearchConceptsBreast cancer riskBreast adipose tissueTissue levelsCancer riskAdipose tissueBenign breast disease controlsIncident breast cancer casesYale-New Haven HospitalBreast-related surgeryAdipose tissue levelsFemale breast cancerCase-control studyBreast cancer casesMean tissue levelsLogistic regression modelsRank sum testHighest quartileSurgical specimenDichlorodiphenyltrichloroethane (DDT) exposureOdds ratioBreast cancerCancer casesDisease controlSum testMean levelsβ‐Benzene hexachloride in breast adipose tissue and risk of breast carcinoma
Zheng T, Holford T, Mayne S, Owens P, Ward B, Carter D, Dubrow R, Zahm S, Boyle P, Tessari J. β‐Benzene hexachloride in breast adipose tissue and risk of breast carcinoma. Cancer 1999, 85: 2212-2218. PMID: 10326700, DOI: 10.1002/(sici)1097-0142(19990515)85:10<2212::aid-cncr16>3.0.co;2-f.Peer-Reviewed Original ResearchConceptsBreast adipose tissueAdipose tissue levelsBreast carcinoma riskBreast carcinoma casesBreast carcinomaAdipose tissueCarcinoma casesCarcinoma riskTissue levelsBenign breast diseaseProgesterone receptor statusPatients age 40Association of exposurePrimary breast carcinomaLogistic regression modelsPostmenopausal womenMenopausal statusParous womenNulliparous womenReceptor statusHighest quartilePotential confoundersBreast diseaseΒ-benzene hexachlorideConnecticut women
1998
Body Mass Index and Risk of Adenocarcinomas of the Esophagus and Gastric Cardia
Chow W, Blot W, Vaughan T, Risch H, Gammon M, Stanford J, Dubrow R, Schoenberg J, Mayne S, Farrow D, Ahsan H, West A, Rotterdam H, Niwa S, Fraumeni J. Body Mass Index and Risk of Adenocarcinomas of the Esophagus and Gastric Cardia. Journal Of The National Cancer Institute 1998, 90: 150-155. PMID: 9450576, DOI: 10.1093/jnci/90.2.150.Peer-Reviewed Original ResearchConceptsBody mass indexEsophageal squamous cell carcinomaNoncardia gastric adenocarcinomaSquamous cell carcinomaGastric cardia adenocarcinomaAdult body mass indexOdds ratioCell carcinomaGastric adenocarcinomaCardia adenocarcinomaGastric cardiaCase patientsMass indexEsophageal adenocarcinomaPopulation-based case-control studyAge groupsRisk of adenocarcinomaAdenocarcinoma of esophagusAnthropometric risk factorsPrevalence of obesityHealthy control subjectsCase-control studyYounger age groupsMagnitude of associationUnited States population
1997
Tobacco, Alcohol, and Socioeconomic Status and Adenocarcinomas of the Esophagus and Gastric Cardia
Gammon M, Ahsan H, Schoenberg J, West A, Rotterdam H, Niwa S, Blot W, Risch H, Dubrow R, Mayne S, Vaughan T, Stanford J, Farrow D, Chow W, Fraumeni J. Tobacco, Alcohol, and Socioeconomic Status and Adenocarcinomas of the Esophagus and Gastric Cardia. Journal Of The National Cancer Institute 1997, 89: 1277-1284. PMID: 9293918, DOI: 10.1093/jnci/89.17.1277.Peer-Reviewed Original ResearchConceptsEsophageal squamous cell carcinomaGastric cardiaSquamous cell carcinomaCell carcinomaGastric adenocarcinomaRisk factorsTumor typesNoncardia gastric adenocarcinomaDuration of smokingCurrent cigarette smokersRisk of esophagealMajor risk factorCase-control studyGastric cardia adenocarcinomaEarly-stage carcinogenesisCigarette smokersHigher ORsControl subjectsIncidence rateSimilar ORsCardia adenocarcinomaEstimates of riskAdenocarcinomaCardiaSmokingSevere Obesity as an Explanatory Factor for the Black/White Difference in Stage at Diagnosis of Breast Cancer
Jones B, Kasl S, Curnen M, Owens P, Dubrow R. Severe Obesity as an Explanatory Factor for the Black/White Difference in Stage at Diagnosis of Breast Cancer. American Journal Of Epidemiology 1997, 146: 394-404. PMID: 9290499, DOI: 10.1093/oxfordjournals.aje.a009292.Peer-Reviewed Original ResearchConceptsSevere obesityBreast cancerWhite womenRacial differencesBlack womenTNM stage IIPrevalence of obesityLogistic regression modelsObserved racial differencesBlack/White DifferencesRetrospective studyOdds ratioHigh prevalenceObesityStage IICancerDiagnosisWomenWhite differencesPrevalenceRegression modelsDifferencesLater stagesDiseaseImportant roleBreast Cancer Risk Factors According to Combined Estrogen and Progesterone Receptor Status: A Case-Control Analysis
Yoo K, Tajima K, Miura S, Takeuchi T, Hirose K, Risch H, Dubrow R. Breast Cancer Risk Factors According to Combined Estrogen and Progesterone Receptor Status: A Case-Control Analysis. American Journal Of Epidemiology 1997, 146: 307-314. PMID: 9270409, DOI: 10.1093/oxfordjournals.aje.a009271.Peer-Reviewed Original ResearchConceptsProgesterone receptor statusHormone receptor statusReceptor statusEstrogen receptor statusRisk factorsBreast cancerAichi Cancer Center HospitalBreast cancer risk factorsDiagnosis/interviewReproductive risk factorsCancer Center HospitalCancer risk factorsGradient of riskBreast cancer casesCase-control analysisPolytomous logistic regressionCancer-free controlsCommon control groupStratification of casesJoint estrogenCenter HospitalMenstrual regularityCigarette smokingCombined EstrogenProgesterone receptor
1996
Malignant melanoma risk factors by anatomic site: A case‐control study and polychotomous logistic regression analysis
Chen Y, Dubrow R, Holford T, Zheng T, Barnhill R, Fine J, Berwick M. Malignant melanoma risk factors by anatomic site: A case‐control study and polychotomous logistic regression analysis. International Journal Of Cancer 1996, 67: 636-643. PMID: 8782651, DOI: 10.1002/(sici)1097-0215(19960904)67:5<636::aid-ijc8>3.0.co;2-v.Peer-Reviewed Original ResearchConceptsMelanoma risk factorsCase-control studyRisk factorsAnatomic sitesSun exposurePopulation-based case-control studySun exposure-related factorsIntermittent sun exposureHistory of sunburnOnly risk factorPolychotomous logistic regression analysisInvasive melanoma casesNumber of neviLogistic regression analysisExposure-related factorsDevelopment of melanomaSex differencesPolychotomous logistic regressionHistologic subtypeMalignant melanomaClothing habitsPigmentary characteristicsMelanoma casesStudy subjectsLogistic regressionTubal sterilization and the risk of endometrial cancer
Castellsagué X, Thompson W, Dubrow R. Tubal sterilization and the risk of endometrial cancer. International Journal Of Cancer 1996, 65: 607-612. PMID: 8598311, DOI: 10.1002/(sici)1097-0215(19960301)65:5<607::aid-ijc9>3.0.co;2-6.Peer-Reviewed Original ResearchConceptsEpithelial endometrial cancerEndometrial cancerTubal sterilizationProtective effectMulticenter population-based case-control studyPopulation-based case-control studyNon-significant protective effectPopulation-based cancer registriesCase-control studyCrude odds ratiosEpithelial endometrial carcinomaYears of ageMethod of contraceptionCancer RegistryEndometrial carcinomaOvarian functionTubal occlusionWomen 20Odds ratioEndogenous estrogensProtective associationEndometrial carcinogenesisWoman's riskHuman studiesCancer
1995
Can mammography screening explain the race difference in stage at diagnosis of breast cancer?
Jones B, Kasl S, Curnen M, Owens P, Dubrow R. Can mammography screening explain the race difference in stage at diagnosis of breast cancer? Cancer 1995, 75: 2103-2113. PMID: 7697601, DOI: 10.1002/1097-0142(19950415)75:8<2103::aid-cncr2820750813>3.0.co;2-2.Peer-Reviewed Original ResearchConceptsBreast cancerWhite womenMammography screeningLate-stage diagnosisPopulation-based dataDevelopment of symptomsLate-stage cancerBlack womenAfrican American womenRace differencesRace-specific analysesScreening historyObserved race differencesRetrospective studyMammographic screeningActive surveillanceConnecticut hospitalsStage cancerCancerDiagnosisSocioeconomic statusWomenStage diagnosisSignificant predictorsAmerican women