2022
The protective effect of rs373863828 on type 2 diabetes does not operate through a body composition pathway in adult Samoans
Hawley NL, Duckham RL, Carlson JC, Naseri T, Reupena MS, Lameko V, Pomer A, Wetzel A, Selu M, Lupematisila V, Unasa F, Vesi L, Fatu T, Unasa S, Faasalele‐Savusa K, Rivara AC, Russell E, Delany JP, Viali S, Kershaw EE, Minster RL, Weeks DE, McGarvey ST. The protective effect of rs373863828 on type 2 diabetes does not operate through a body composition pathway in adult Samoans. Obesity 2022, 30: 2468-2476. PMID: 36284436, PMCID: PMC10111239, DOI: 10.1002/oby.23559.Peer-Reviewed Original ResearchConceptsFat-free massType 2 diabetesFat distributionProtective effectBody compositionFavorable body fat distributionDual-energy X-ray absorptiometry-derived body compositionBody fat distributionGreater fat-free massPercent body fatBody size/compositionAssociation of genotypesRs373863828 genotypeVisceral adiposityHigher BMIAdult SamoansRole of fatGreater BMILean massBody fatLower oddsParadoxical associationTissue-specific mechanismsA alleleDiabetes
2021
C‐reactive protein in adult Samoans: Population variation and physiological correlates
Rivara AC, Corley M, Choy CC, Duckham RL, Pomer A, Reupena MS, Viali S, Naseri T, Kershaw EE, Crouter SE, McGarvey ST, Bribiescas RG, Valeggia C, Hawley NL. C‐reactive protein in adult Samoans: Population variation and physiological correlates. American Journal Of Human Biology 2021, 34: e23646. PMID: 34260111, PMCID: PMC8758804, DOI: 10.1002/ajhb.23646.Peer-Reviewed Original ResearchConceptsC-reactive proteinBody mass indexCardiometabolic disease riskMeasures of adiposityAdult SamoansCRP correlateDisease riskSerum C-reactive proteinMeasures of BMICardiometabolic risk markersPercent body fatSex-dependent associationsCardiometabolic markersCardiometabolic riskCRP quartileMass indexUnadjusted analysesRisk markersBody fatKruskal-Wallis testAdiposityPacific Islander populationsSpearman rank correlationFirst examinationRank correlation