2022
Childhood asthma and household exposures to nitrogen dioxide and fine particles: a triple-crossover randomized intervention trial
Gent JF, Holford TR, Bracken MB, Plano JM, McKay LA, Sorrentino KM, Koutrakis P, Leaderer BP. Childhood asthma and household exposures to nitrogen dioxide and fine particles: a triple-crossover randomized intervention trial. Journal Of Asthma 2022, 60: 744-753. PMID: 35796019, PMCID: PMC10162040, DOI: 10.1080/02770903.2022.2093219.Peer-Reviewed Original ResearchConceptsLevels of NOPersistent asthmaAsthma symptomsIntervention trialsNumber of asthmaDays of treatmentSymptom daysAsthma morbidityChildhood asthmaTreatment periodAsthmaCrossover designHousehold exposureSymptomsModest reductionTreatment effectsTreatmentGas stovesTrialsExposureTriple crossoverInterventionChildrenMixed modelsFurther research
2016
The Impact of Infectious Disease Specialist Consultation for Staphylococcus aureus Bloodstream Infections: A Systematic Review
Paulsen J, Solligård E, Damås JK, DeWan A, Åsvold BO, Bracken MB. The Impact of Infectious Disease Specialist Consultation for Staphylococcus aureus Bloodstream Infections: A Systematic Review. Open Forum Infectious Diseases 2016, 3: ofw048. PMID: 27047985, PMCID: PMC4817315, DOI: 10.1093/ofid/ofw048.Peer-Reviewed Original ResearchAureus bloodstream infectionInfectious disease specialistsBloodstream infectionsDisease specialistsSystematic reviewInfectious disease specialist consultationS aureus bloodstream infectionsStaphylococcus aureus bloodstream infectionsRate of complicationsSevere bloodstream infectionsCause mortalitySurvival benefitSpecialist consultationStudy protocolEligible studiesCommon causeObservational studyHigh riskLower riskNarrative reviewInfectionTrialsStaphylococcus aureusConsultationRisk
2015
Call to improve transparency of trials of non-regulated interventions
Dal-Ré R, Bracken MB, Ioannidis JP. Call to improve transparency of trials of non-regulated interventions. The BMJ 2015, 350: h1323. PMID: 25820265, DOI: 10.1136/bmj.h1323.Peer-Reviewed Original Research
2014
Re‐analysis of the PREGNANT trial confirms that vaginal progesterone reduces the rate of preterm birth in women with a sonographic short cervix
McKay LA, Holford TR, Bracken MB. Re‐analysis of the PREGNANT trial confirms that vaginal progesterone reduces the rate of preterm birth in women with a sonographic short cervix. Ultrasound In Obstetrics And Gynecology 2014, 43: 596-597. PMID: 24585456, DOI: 10.1002/uog.13331.Peer-Reviewed Original Research
2000
Clinical Measurement, Statistical Analysis, and Risk-Benefit: Controversies from Trials of Spinal Injury
Bracken M, Aldrich E, Herr D, Hitchon P, Holford T, Marshall L, Nockels R, Pascale V, Shepard M, Sonntag V, Winn H, Young W. Clinical Measurement, Statistical Analysis, and Risk-Benefit: Controversies from Trials of Spinal Injury. Journal Of Trauma And Acute Care Surgery 2000, 48: 558-561. PMID: 10744306, DOI: 10.1097/00005373-200003000-00036.Commentaries, Editorials and LettersConceptsNational Acute Spinal Cord Injury StudyAcute Spinal Cord Injury StudyAcute spinal cord injurySpinal Cord Injury StudyClinical measurementsHigh-dose methylprednisoloneSecondary neuronal damageSpinal cord injuryRisk benefitNeuronal damageFunctional recoverySafety profileCord injuryPharmacologic agentsSpinal injuryInjury studiesInnovative therapiesTrialsStatistical analysisInjuryMulticenterMethylprednisoloneSeries of trialsTherapyPrevention
1994
Clinically useful measures of effect in binary analyses of randomized trials
Sinclair J, Bracken M. Clinically useful measures of effect in binary analyses of randomized trials. Journal Of Clinical Epidemiology 1994, 47: 881-889. PMID: 7730891, DOI: 10.1016/0895-4356(94)90191-0.Peer-Reviewed Original ResearchConceptsOdds ratioTreatment effectsHigher baseline riskRelative risk reductionRandomized clinical trialsControl group risksGroups of trialsLarge treatment effectsPhysician appreciationRandomized trialsRisk ratioClinical trialsRelative riskBaseline riskTreatment decisionsClinical questionsRisk differenceTrialsSingle trialRisk reductionRiskGroup riskPhysiciansAbsolute effectUseful measure
1991
Treatment of acute spinal cord injury with methylprednisolone: results of a multicenter, randomized clinical trial.
Bracken M. Treatment of acute spinal cord injury with methylprednisolone: results of a multicenter, randomized clinical trial. Journal Of Neurotrauma 1991, 8 Suppl 1: s47-50; discussion s51-2. PMID: 1920461.Peer-Reviewed Original ResearchConceptsAcute spinal cord injurySpinal cord injuryCord injuryAdministration of methylprednisoloneApparent contraindicationsNeurological improvementClinical trialsPermanent paralysisMethylprednisoloneLow dosesInjuryAdministrationDosesTrialsTreatmentMulticenterPlaceboContraindicationsNaloxoneParalysisDoseA Randomized, Controlled Trial of Methylprednisolone or Naloxone in the Treatment of Acute Spinal-Cord Injury
BRACKEN M, SHEPARD M, COLLINS W, HOLFORD T, YOUNG W, BASKIN D, EISENBERG H, FLAMM E, LEOSUMMERS L, MAROON J, MARSHALL L, PEROT P, PIEPMEIER J, SONNTAG V, WAGNER F, WILBERGER J, WINN H. A Randomized, Controlled Trial of Methylprednisolone or Naloxone in the Treatment of Acute Spinal-Cord Injury. Survey Of Anesthesiology 1991, 35: 50. DOI: 10.1097/00132586-199102000-00048.Peer-Reviewed Original Research
1989
Meta-analysis of the relationship between asymptomatic bacteriuria and preterm delivery/low birth weight.
Romero R, Oyarzun E, Mazor M, Sirtori M, Hobbins J, Bracken M. Meta-analysis of the relationship between asymptomatic bacteriuria and preterm delivery/low birth weight. Obstetrics And Gynecology 1989, 73: 576-82. PMID: 2927852.Peer-Reviewed Original ResearchConceptsLow birth weightUntreated asymptomatic bacteriuriaRate of LBWAsymptomatic bacteriuriaPreterm deliveryBirth weightAntibiotic treatmentClinical trialsOccurrence of LBWPrematurity/low birth weightRisk of LBWPercentage point differenceRandomized clinical trialsNonbacteriuric patientsCohort studyEpidemiologic evidenceBacteriuriaControl trialMeta-AnalysisStudy designStrong associationTrialsRiskTwo-thirdsDelivery
1980
An evaluation of the usefulness of x-ray pelvimetry: Comparison of the Thoms and modified Ball methods with manual pelvimetry
Fine E, Bracken M, Berkowitz R. An evaluation of the usefulness of x-ray pelvimetry: Comparison of the Thoms and modified Ball methods with manual pelvimetry. American Journal Of Obstetrics And Gynecology 1980, 137: 15-20. PMID: 7369283, DOI: 10.1016/0002-9378(80)90378-6.Peer-Reviewed Original ResearchConceptsX-ray pelvimetryCephalopelvic disproportionCephalic presentationVaginal deliveryPotential oncogenic riskSafe vaginal deliveryObstetric outcomesVertex presentationPrognostic indicatorFetal irradiationOncogenic riskFull trialPelvimetryManual assessmentHigh ratePelvisPresentationDisproportionDeliveryPatientsBall techniqueDiagnosisTrials