1999
Magnetic resonance imaging and neurological recovery in acute spinal cord injury: observations from the National Acute Spinal Cord Injury Study 3
Shepard M, Bracken M. Magnetic resonance imaging and neurological recovery in acute spinal cord injury: observations from the National Acute Spinal Cord Injury Study 3. Spinal Cord 1999, 37: 833-837. PMID: 10602525, DOI: 10.1038/sj.sc.3100927.Peer-Reviewed Original ResearchConceptsMagnetic resonance imagingAcute spinal cord injurySpinal cord injuryCord injuryMotor functionResonance imagingSpinal cord injury centerBlind clinical trialInitial neurological examinationInitial clinical examinationLight touch sensationComplete cord injurySpinal cord surgeryMultiple logistic regressionNational InstitutePresence of edemaComplete injuryNeurological recoveryRandomized patientsStudy drugCord edemaNeurological statusCord surgeryNeurological examinationNeurological assessment
1984
Efficacy of Methylprednisolone in Acute Spinal Cord Injury
Bracken M, Collins W, Freeman D, Shepard M, Wagner F, Silten R, Hellenbrand K, Ransohoff J, Hunt W, Perot P, Grossman R, Green B, Eisenberg H, Rifkinson N, Goodman J, Meagher J, Fischer B, Clifton G, Flamm E, Rawe S. Efficacy of Methylprednisolone in Acute Spinal Cord Injury. JAMA 1984, 251: 45-52. PMID: 6361287, DOI: 10.1001/jama.1984.03340250025015.Peer-Reviewed Original ResearchConceptsAcute spinal cord injurySpinal cord injuryCord injuryEarly case fatalityEfficacy of methylprednisoloneHigh-dose regimenLight touch sensationHigh-dose protocolGroups six weeksNeurological recoveryCase fatalityWound infectionStandard doseMotor functionInitial lesionHigh doseOperative siteSix weeksInjuryMethylprednisoloneTreatment effectsTouch sensationDoseEfficacyMulticenter