2022
Effect of an Active vs Expectant Management Strategy on Successful Resolution of Pregnancy Among Patients With a Persisting Pregnancy of Unknown Location: The ACT or NOT Randomized Clinical Trial
Barnhart K, Hansen K, Stephenson M, Usadi R, Steiner A, Cedars M, Jungheim E, Hoeger K, Krawetz S, Mills B, Alston M, Coutifaris C, Senapati S, Sonalkar S, Diamond M, Wild R, Rosen M, Sammel M, Santoro N, Eisenberg E, Huang H, Zhang H. Effect of an Active vs Expectant Management Strategy on Successful Resolution of Pregnancy Among Patients With a Persisting Pregnancy of Unknown Location: The ACT or NOT Randomized Clinical Trial. Obstetrical & Gynecological Survey 2022, 77: 24-26. DOI: 10.1097/01.ogx.0000805156.32421.70.Peer-Reviewed Original Research
2017
Onset of human preterm and term birth is related to unique inflammatory transcriptome profiles at the maternal fetal interface
Bukowski R, Sadovsky Y, Goodarzi H, Zhang H, Biggio JR, Varner M, Parry S, Xiao F, Esplin SM, Andrews W, Saade GR, Ilekis JV, Reddy UM, Baldwin DA. Onset of human preterm and term birth is related to unique inflammatory transcriptome profiles at the maternal fetal interface. PeerJ 2017, 5: e3685. PMID: 28879060, PMCID: PMC5582610, DOI: 10.7717/peerj.3685.Peer-Reviewed Original ResearchMaternal-fetal interfacePreterm birthTerm birthsFetal interfaceDownregulation of chemokinesAbsence of laborBurden of diseasePremature deliveryCesarean deliveryOverall mortalityChemokine expressionTerm laborNeonatal mortalityPregnant womenUterine fundusTerm parturitionHuman pretermPlacental functionMaternal bloodMultiple pathwaysFetal bloodPretermExpression profilesImmune rejectionImmune system
2014
Maternal serum serpin B7 is associated with early spontaneous preterm birth
Parry S, Zhang H, Biggio J, Bukowski R, Varner M, Xu Y, Andrews WW, Saade GR, Esplin MS, Leite R, Ilekis J, Reddy UM, Sadovsky Y, Blair IA, Research E. Maternal serum serpin B7 is associated with early spontaneous preterm birth. American Journal Of Obstetrics And Gynecology 2014, 211: 678.e1-678.e12. PMID: 24954659, PMCID: PMC4254341, DOI: 10.1016/j.ajog.2014.06.035.Peer-Reviewed Original ResearchConceptsSpontaneous preterm birthEarly spontaneous preterm birthPreterm birthMaternal serumSerum samplesPrevious spontaneous preterm birthSubsequent preterm deliveryProtein expressionLower gestational ageGestational age windowsCase-control studyCandidate protein expressionSerum proteomic analysisIndividual serum samplesPooled serum samplesSpontaneous pretermPreterm deliveryWeeks' gestationGestational ageTerm deliveryPregnant womenSerum biomarkersSerum concentrationsFetal membranesClinical sites