2014
Consortium analysis of gene and gene–folate interactions in purine and pyrimidine metabolism pathways with ovarian carcinoma risk
Kelemen LE, Terry KL, Goodman MT, Webb PM, Bandera EV, McGuire V, Rossing MA, Wang Q, Dicks E, Tyrer JP, Song H, Kupryjanczyk J, Dansonka‐Mieszkowska A, Plisiecka‐Halasa J, Timorek A, Menon U, Gentry‐Maharaj A, Gayther SA, Ramus SJ, Narod SA, Risch HA, McLaughlin JR, Siddiqui N, Glasspool R, Paul J, Carty K, Gronwald J, Lubiński J, Jakubowska A, Cybulski C, Kiemeney LA, Massuger LF, van Altena A, Aben KK, Olson SH, Orlow I, Cramer DW, Levine DA, Bisogna M, Giles GG, Southey MC, Bruinsma F, Kjær S, Høgdall E, Jensen A, Høgdall CK, Lundvall L, Engelholm S, Heitz F, du Bois A, Harter P, Schwaab I, Butzow R, Nevanlinna H, Pelttari LM, Leminen A, Thompson PJ, Lurie G, Wilkens LR, Lambrechts D, Van Nieuwenhuysen E, Lambrechts S, Vergote I, Beesley J, Investigators A, Fasching P, Beckmann M, Hein A, Ekici A, Doherty J, Wu A, Pearce C, Pike M, Stram D, Chang‐Claude J, Rudolph A, Dörk T, Dürst M, Hillemanns P, Runnebaum I, Bogdanova N, Antonenkova N, Odunsi K, Edwards R, Kelley J, Modugno F, Ness R, Karlan B, Walsh C, Lester J, Orsulic S, Fridley B, Vierkant R, Cunningham J, Wu X, Lu K, Liang D, Hildebrandt M, Weber R, Iversen E, Tworoger S, Poole E, Salvesen H, Krakstad C, Bjorge L, Tangen I, Pejovic T, Bean Y, Kellar M, Wentzensen N, Brinton L, Lissowska J, Garcia‐Closas M, Campbell I, Eccles D, Whittemore A, Sieh W, Rothstein J, Anton‐Culver H, Ziogas A, Phelan C, Moysich K, Goode E, Schildkraut J, Berchuck A, Pharoah P, Sellers T, Brooks‐Wilson A, Cook L, Le N. Consortium analysis of gene and gene–folate interactions in purine and pyrimidine metabolism pathways with ovarian carcinoma risk. Molecular Nutrition & Food Research 2014, 58: 2023-2035. PMID: 25066213, PMCID: PMC4197821, DOI: 10.1002/mnfr.201400068.Peer-Reviewed Original ResearchCarcinomaCase-Control StudiesDietDietary SupplementsDihydrouracil Dehydrogenase (NADP)Energy IntakeFemaleFolic AcidFolic Acid DeficiencyGenetic Predisposition to DiseaseGenome-Wide Association StudyGlobal HealthHumansMultivariate AnalysisNeoplasm ProteinsOvarian NeoplasmsPolymorphism, Single NucleotideRisk FactorsWhite People
2011
Genetic Effects and Modifiers of Radiotherapy and Chemotherapy on Survival in Pancreatic Cancer
Zeng H, Yu H, Lu L, Jain D, Kidd MS, Saif MW, Chanock SJ, Hartge P, Risch H. Genetic Effects and Modifiers of Radiotherapy and Chemotherapy on Survival in Pancreatic Cancer. Pancreas 2011, 40: 657-663. PMID: 21487324, PMCID: PMC3116071, DOI: 10.1097/mpa.0b013e31821268d1.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overATP Binding Cassette Transporter, Subfamily G, Member 2ATP-Binding Cassette TransportersCase-Control StudiesConnecticutDihydrouracil Dehydrogenase (NADP)FemaleGenetic MarkersGenetic VariationGenome-Wide Association StudyHumansMaleMiddle AgedNeoplasm ProteinsPancreatic NeoplasmsPolymorphism, Single NucleotidePrognosisProportional Hazards ModelsSerpinsSurvival AnalysisTreatment OutcomeConceptsPancreatic cancerOverall survivalCancer survivalProportional hazards regression modelsSurvival of patientsPopulation-based studyPancreatic cancer survivalHazards regression modelsGerm-line genetic variationEvidence of associationClinical outcomesCancer patientsTreatment outcomesTreatment responseSignificant associationPatientsCancerPrevious genome-wide association study dataRadiotherapyPutative markerGenetic polymorphismsSurvivalDPYD geneChemotherapyEvidence of interaction