Axonal guidance signaling pathway interacting with smoking in modifying the risk of pancreatic cancer: a gene- and pathway-based interaction analysis of GWAS data
Tang H, Wei P, Duell EJ, Risch HA, Olson SH, Bueno-de-Mesquita HB, Gallinger S, Holly EA, Petersen G, Bracci PM, McWilliams RR, Jenab M, Riboli E, Tjønneland A, Boutron-Ruault MC, Kaaks R, Trichopoulos D, Panico S, Sund M, Peeters PH, Khaw KT, Amos CI, Li D. Axonal guidance signaling pathway interacting with smoking in modifying the risk of pancreatic cancer: a gene- and pathway-based interaction analysis of GWAS data. Carcinogenesis 2014, 35: 1039-1045. PMID: 24419231, PMCID: PMC4004205, DOI: 10.1093/carcin/bgu010.Peer-Reviewed Original ResearchConceptsIngenuity Pathway AnalysisKEGG pathwaysSingle nucleotide polymorphism (SNP) levelAxonal guidanceGenome-wide levelGene ontology pathwaysSalivary secretion pathwaysSlit/RoboGenes/SNPsOntology pathwaysPolymorphism levelSecretion pathwayGWAS dataGene setsPancreatic Cancer Case-Control ConsortiumCanonical pathwaysPathway analysisAxon guidanceGenesSNPsRegion SNPsPathwayIPA analysisPancreatic cancerDiscovery studies