2017
Investigating the Impact of Maternal Residential Mobility on Identifying Critical Windows of Susceptibility to Ambient Air Pollution During Pregnancy
Warren JL, Son JY, Pereira G, Leaderer BP, Bell ML. Investigating the Impact of Maternal Residential Mobility on Identifying Critical Windows of Susceptibility to Ambient Air Pollution During Pregnancy. American Journal Of Epidemiology 2017, 187: 992-1000. PMID: 29053768, PMCID: PMC5928458, DOI: 10.1093/aje/kwx335.Peer-Reviewed Original ResearchConceptsLow birth weightTerm low birth weightMaternal residential mobilityBirth weightCritical windowBirth cohortWeekly exposurePregnancy week 16Adverse birth outcomesWindow of susceptibilityAmbient air pollutionPregnancy windowsBirth outcomesWeek 16Mother's residencePM10 exposurePregnancyResidential addressesExposure misclassificationDisease developmentCohortAir pollutionExposureAerodynamic diameterPossible mechanism
2015
Distributions of heavy metals in maternal and cord blood and the association with infant birth weight in China.
Hu X, Zheng T, Cheng Y, Holford T, Lin S, Leaderer B, Qiu J, Bassig BA, Shi K, Zhang Y, Niu J, Zhu Y, Li Y, Guo H, Chen Q, Zhang J, Xu S, Jin Y. Distributions of heavy metals in maternal and cord blood and the association with infant birth weight in China. The Journal Of Reproductive Medicine 2015, 60: 21-9. PMID: 25745747, PMCID: PMC4961246.Peer-Reviewed Original ResearchConceptsInfant birth weightCord blood samplesBirth weightCord bloodBlood samplesChinese pregnant womenMother-infant pairsBirth outcomesSerum levelsPregnant womenPrenatal exposureSerum concentrationsChinese infantsMultiple linear regression analysisLarger sample sizeLinear regression analysisSignificant associationChinese womenPilot studyBloodRegression analysisNewbornsAssociationWomenHigh concentrations
2014
Asthma medication use during pregnancy, wheeze and estimated exposure to ambient nitrogen dioxide
Gent JF, Kezik JM, Hill ME, McKay LA, Holford TR, Leaderer BP, Bracken MB. Asthma medication use during pregnancy, wheeze and estimated exposure to ambient nitrogen dioxide. European Respiratory Journal 2014, 45: 538-540. PMID: 25537555, PMCID: PMC4331059, DOI: 10.1183/09031936.00161514.Peer-Reviewed Original ResearchConceptsAsthma medication useMedication usePregnant womenRisk of wheezePoor pulmonary functionAdverse health outcomesPregnant asthmaticsAsthma exacerbationsAsthma medicationsPerinatal complicationsPulmonary functionFetal growthHealth outcomesPregnancyNO2 exposureWheezeAsthmaMedicationsWomenAmbient nitrogen dioxideMothersMinimal effectExposureAsthmaticsExacerbation
2012
Relationship between birth weight and exposure to airborne fine particulate potassium and titanium during gestation
Bell ML, Belanger K, Ebisu K, Gent JF, Leaderer BP. Relationship between birth weight and exposure to airborne fine particulate potassium and titanium during gestation. Environmental Research 2012, 117: 83-89. PMID: 22705336, PMCID: PMC3418490, DOI: 10.1016/j.envres.2012.05.004.Peer-Reviewed Original ResearchConceptsLow birth weightBirth weightAdverse pregnancy outcomesPregnancy outcomesTerm infantsAirborne fine particulate matterStudy populationIQR increaseMothers' exposureAfrican American mothersFirst birthInfantsEffect estimatesConfidence intervalsWhite mothersPregnancyHealth impactsRiskExposureFine particulate matterMothersMost studiesGestationWeight
2010
Prenatal Exposure to Fine Particulate Matter and Birth Weight
Bell ML, Belanger K, Ebisu K, Gent JF, Lee HJ, Koutrakis P, Leaderer BP. Prenatal Exposure to Fine Particulate Matter and Birth Weight. Epidemiology 2010, 21: 884-891. PMID: 20811286, PMCID: PMC3055585, DOI: 10.1097/ede.0b013e3181f2f405.Peer-Reviewed Original Research
2006
Comparison of parental reports of smoking and residential air nicotine concentrations in children
Gehring U, Leaderer B, Heinrich J, Oldenwening M, Giovannangelo M, Nordling E, Merkel G, Hoek G, Bellander T, Brunekreef B. Comparison of parental reports of smoking and residential air nicotine concentrations in children. Occupational And Environmental Medicine 2006, 63: 766. PMID: 16912089, PMCID: PMC2077986, DOI: 10.1136/oem.2006.027151.Peer-Reviewed Original ResearchConceptsAir nicotine concentrationsEnvironmental tobacco smokeUrinary cotinine measurementsNicotine concentrationsETS exposureResidential exposureCotinine measurementsPredictive valueAir nicotine levelsUrinary cotinine levelsUrinary cotinine concentrationsChildren's residential exposureQuestionnaire reportsDose-response fashionResidential ETS exposureNegative predictive valuePositive predictive valueAir nicotineCotinine levelsCotinine concentrationsSymptomatic childrenOccasional smokersSymptom statusTobacco smokeNicotine levels
2005
Indoor nitrous acid and respiratory symptoms and lung function in adults
Jarvis D, Leaderer B, Chinn S, Burney P. Indoor nitrous acid and respiratory symptoms and lung function in adults. Thorax 2005, 60: 474. PMID: 15923247, PMCID: PMC1747426, DOI: 10.1136/thx.2004.032177.Peer-Reviewed Original ResearchConceptsLung functionRespiratory symptomsHealth effectsIndoor NO2Lower lung functionMore respiratory symptomsNon-significant increaseFEV1/Expiratory volumeVital capacityRelevant confoundersSecond percentageEpidemiological studiesSignificant associationSymptomsHome levelAssociationAdultsOutdoor levelsHigh levelsLevelsFailureConfoundersMonths
2003
Cigarette smoking and risk of non-Hodgkin lymphoma subtypes among women
Morton L, Holford T, Leaderer B, Boyle P, Zahm S, Zhang Y, Flynn S, Tallini G, Zhang B, Owens P, Zheng T. Cigarette smoking and risk of non-Hodgkin lymphoma subtypes among women. British Journal Of Cancer 2003, 89: 2087-2092. PMID: 14647142, PMCID: PMC2376853, DOI: 10.1038/sj.bjc.6601388.Peer-Reviewed Original ResearchConceptsNon-Hodgkin lymphomaCumulative lifetime exposureCurrent smoking statusCigarette smokingNHL subtypesFollicular lymphomaLifetime exposurePopulation-based case-control studyRisk of NHLEtiology of NHLNon-Hodgkin lymphoma subtypesDuration of smokingIntensity of smokingPrevious epidemiologic studiesCase-control studyPopulation-based controlsHistologic typeSmoking statusIncident casesTumor gradeLymphoma subtypesEpidemiologic studiesSmokingImmunologic typeLymphoma
2001
Maternal Caffeine Intake and Intrauterine Growth Retardation
Grosso L, Rosenberg K, Belanger K, Saftlas A, Leaderer B, Bracken M. Maternal Caffeine Intake and Intrauterine Growth Retardation. Epidemiology 2001, 12: 447-455. PMID: 11428387, DOI: 10.1097/00001648-200107000-00015.Peer-Reviewed Original ResearchConceptsIntrauterine growth retardationMonth 7Fetal growthMonths 1Caffeine consumptionGrowth retardationMaternal caffeine consumptionMaternal caffeine intakeThird trimesterCigarette smokingLiveborn infantsEffect modificationCaffeine intakeSoda drinkingPregnancyAdverse effectsLittle evidenceCaffeine associationCaffeineRetardationTrimesterSmokingInfantsIntakeWomen
2000
Particulate Matter and Carbon Monoxide in Highland Guatemala: Indoor and Outdoor Levels from Traditional and Improved Wood Stoves and Gas Stoves
Naeher L, Leaderer B, Smith K. Particulate Matter and Carbon Monoxide in Highland Guatemala: Indoor and Outdoor Levels from Traditional and Improved Wood Stoves and Gas Stoves. Indoor Air 2000, 10: 200-205. PMID: 10979201, DOI: 10.1034/j.1600-0668.2000.010003200.x.Peer-Reviewed Original ResearchModel for the Analysis of Binary Time Series of Respiratory Symptoms
Zhang H, Triche E, Leaderer B. Model for the Analysis of Binary Time Series of Respiratory Symptoms. American Journal Of Epidemiology 2000, 151: 1206-1215. PMID: 10905533, DOI: 10.1093/oxfordjournals.aje.a010171.Peer-Reviewed Original ResearchConceptsDuration of symptomsRespiratory symptomsNew episodesStuffy nosePrior historyHistory of allergyDaily respiratory symptomsInfant Health StudyMeteorologic changesHealth StudySymptomsEpidemiologic researchDay careMarital statusIncidenceEnvironmental epidemiologic researchEpisodesMothersDurationSulfate levelsHusband's levelDemographic variablesNoseHigh levelsAllergy
1999
Environmental Tobacco Smoke Exposure and Small-for-Gestational-Age Birth
Sadler L, Belanger K, Saftlas A, Leaderer B, Hellenbrand K, McSharry J, Bracken M. Environmental Tobacco Smoke Exposure and Small-for-Gestational-Age Birth. American Journal Of Epidemiology 1999, 150: 695-705. PMID: 10512423, DOI: 10.1093/oxfordjournals.aje.a010072.Peer-Reviewed Original ResearchMeSH KeywordsAdultAge DistributionBirth WeightCohort StudiesConnecticutFemaleFetal Growth RetardationHumansInfant, NewbornInfant, Small for Gestational AgeInterviews as TopicLinear ModelsMaternal ExposureMultivariate AnalysisPregnancyPregnancy Trimester, ThirdProspective StudiesRetrospective StudiesRisk FactorsTobacco Smoke PollutionConceptsEnvironmental tobacco smoke exposureTobacco smoke exposureGestational-age birthsEnvironmental tobacco smokeSmoke exposureSGA birthThird trimesterTobacco smokeBirth weight differenceIntensity of exposureCohort studyMedian durationPostpartum interviewsUnexposed mothersUpper middle class groupBirth weightEffects of exposureFetal growthMultivariate logisticOdds ratioStudy populationLow levelsWomenBirthTrimesterHealthy Women's PEF Variations with Ambient Summer Concentrations of PM10, PM2.5, SO4 2 −, H+, and O3
NAEHER L, HOLFORD T, BECKETT W, BELANGER K, TRICHE E, BRACKEN M, LEADERER B. Healthy Women's PEF Variations with Ambient Summer Concentrations of PM10, PM2.5, SO4 2 −, H+, and O3. American Journal Of Respiratory And Critical Care Medicine 1999, 160: 117-125. PMID: 10390388, DOI: 10.1164/ajrccm.160.1.9808153.Peer-Reviewed Original ResearchConceptsPeak expiratory flowPEF variationEvening peak expiratory flowMorning peak expiratory flowOutdoor monitoring sitePeak flow meterAmbient air pollutionMicrograms/m3Expiratory flowPhysiologic effectsPEF measurementsOnly exposureConcurrent measuresExposureMeteorologic variablesFine particulate sulfateDaily
1998
Correlates of Residential Wiring Code Used in Studies of Health Effects of Residential Electromagnetic Fields
Bracken M, Belanger K, Hellenbrand K, Addesso K, Patel S, Triche E, Leaderer B. Correlates of Residential Wiring Code Used in Studies of Health Effects of Residential Electromagnetic Fields. American Journal Of Epidemiology 1998, 148: 467-474. PMID: 9737559, DOI: 10.1093/oxfordjournals.aje.a009672.Peer-Reviewed Original ResearchSpontaneous Abortion and Exposure to Electric Blankets and Heated Water Beds
Belanger K, Leaderer B, Hellenbrand K, Holford T, McSharry J, Power M, Bracken M. Spontaneous Abortion and Exposure to Electric Blankets and Heated Water Beds. Epidemiology 1998, 9: 36-42. PMID: 9430266, DOI: 10.1097/00001648-199801000-00009.Peer-Reviewed Original ResearchConceptsElectric blanket useSpontaneous abortionPregnancy lossBlanket useEarly pregnancy lossHeated water bedsTime of conceptionMonth of conceptionWire code categoriesWeeks' gestationProspective studyEarly pregnancyUnadjusted analysesBed useGreater riskPregnancyAbortionDose responseWomenRiskElectric bedElectric blanketExposureSlight increaseGestation
1996
Asthma among Puerto Rican Hispanics: a multi-ethnic comparison study of risk factors.
Beckett W, Belanger K, Gent J, Holford T, Leaderer B. Asthma among Puerto Rican Hispanics: a multi-ethnic comparison study of risk factors. American Journal Of Respiratory And Critical Care Medicine 1996, 154: 894-899. PMID: 8887582, DOI: 10.1164/ajrccm.154.4.8887582.Peer-Reviewed Original ResearchConceptsRisk factorsPuerto Rican HispanicsSocioeconomic statusHispanic ethnicityHispanic mothersEnvironmental tobacco smoke exposureIndependent risk factorPhysician-diagnosed asthmaPrevalence of asthmaTobacco smoke exposureStrong risk factorAfrican American ethnicityEnvironmental risk factorsYr of ageLow socioeconomic statusStudy of asthmaNon-Hispanic whitesMo of ageActive smokingAsthmatic childrenSmoke exposureChildhood asthmaCigarette smokersMaternal ageMaternal historyMaternal Caffeine Consumption and Spontaneous Abortion: A Prospective Cohort Study
Dlugosz L, Belanger K, Hellenbrand K, Holford T, Leaderer B, Bracken M. Maternal Caffeine Consumption and Spontaneous Abortion: A Prospective Cohort Study. Epidemiology 1996, 7: 250-255. PMID: 8728437, DOI: 10.1097/00001648-199605000-00008.Peer-Reviewed Original ResearchConceptsSpontaneous abortionCaffeine consumptionYale-New Haven HospitalMaternal caffeine consumptionProspective cohort studyCohort studyEarly pregnancyPregnant womenOdds ratioSoda drinkingElevated riskCaffeine beveragesBeverage consumptionCaffeine beverage consumptionCigarette useFirst monthPregnancySixteenth weekObserved associationsAbortionCup of teaCaffeineTeaGestationHospital
1995
Measurement of Exposure to Environmental Tobacco Smoke in Pregnant Women
O'Connor T, Holford T, Leaderer B, Hammond S, Bracken M. Measurement of Exposure to Environmental Tobacco Smoke in Pregnant Women. American Journal Of Epidemiology 1995, 142: 1315-1321. PMID: 7503052, DOI: 10.1093/oxfordjournals.aje.a117599.Peer-Reviewed Original ResearchConceptsUrine cotinineEnvironmental tobacco smokePregnant womenTobacco smokeWork exposureAir nicotine concentrationsSelf-reported exposurePersonal air monitorsExposure assessment methodsAir nicotineMeasurement of exposureHome exposureCotinineNicotine concentrationsExposure classificationWomenCohen's kappaExposureSpearman rank-order correlation coefficientAir monitorsRank-order correlation coefficientKappaSocial exposureSmokeHigh levelsThe accuracy of environmental tobacco smoke exposure measures among asthmatic children
Emerson J, Hovell M, Meltzer S, Zakarian J, Hofstetter C, Wahlgren D, Leaderer B, Meltzer E. The accuracy of environmental tobacco smoke exposure measures among asthmatic children. Journal Of Clinical Epidemiology 1995, 48: 1251-1259. PMID: 7561987, DOI: 10.1016/0895-4356(95)00021-u.Peer-Reviewed Original ResearchConceptsResidential ETS exposureETS exposureAsthmatic childrenParent-report measuresEnvironmental tobacco smoke exposureResidential exposureUrine cotinine assayTobacco smoke exposureChildren's residential exposureTest-retest reliability assessmentSmoke exposureCotinine assaysHome exposureEpidemiological investigationsClinical programsExposure measuresConstruct validity testParent reportExposureDiscriminant validityChildrenReportNicotineMeasuresEXPOSURE TO ELECTROMAGNETIC FIELDS DURING PREGNANCY WITH EMPHASIS ON ELECTRICALLY HEATED BEDS
Bracken M, Belanger K, Hellenbrand K, Dlugosz L, Holford T, McSharry J, Addesso K, Leaderer B. EXPOSURE TO ELECTROMAGNETIC FIELDS DURING PREGNANCY WITH EMPHASIS ON ELECTRICALLY HEATED BEDS. Epidemiology 1995, 6: 263-270. PMID: 7619934, DOI: 10.1097/00001648-199505000-00013.Peer-Reviewed Original ResearchConceptsFetal growth retardationGrowth retardationBed useIntrauterine growth retardationVideo display terminal useDose-response relationPersonal monitorsEMF exposureTime-weighted analysisMonitoring of exposureThird trimesterProspective studyFetal growthWire codesHome measurementsReproductive outcomesHuman studiesPregnancyStudy designVideo display terminalsExposure measuresHours of useMeaningful increaseRiskExposure