Infectious Diseases
Laboratory Science
The Department of Epidemiology of Microbial Diseases has an established record of public health discovery through laboratory science. In the school’s first century, YSPH led the fight against poliomyelitis, housed the Arbovirus Research Unit which moved from the Rockefeller Foundation to Yale in 1964 (and was home to Nobel prize-winning scientist Max Theiler and other prominent scientists), as well as the WHO serum bank. Today, Yale is home to several modern laboratories that address vector-borne diseases transmitted by tsetse flies, ticks, mosquitoes and sand flies. In addition, our scientists are pursuing solutions to respiratory ailments, antibiotic resistance, diagnostic testing, vaccine development and infections related to STIs and intravenous drug use.
Recent Publications
2024
- Factors influencing adverse events following COVID-19 vaccination.Villanueva P, McDonald E, Croda J, Croda MG, Dalcolmo M, Dos Santos G, Jardim B, Lacerda M, Lynn DJ, Marshall H, Oliveira RD, Rocha J, Sawka A, Val F, Pittet LF, Messina NL, Curtis N. Hum Vaccin Immunother. 2024 Dec 31; 2024 Mar 6. PMID: 38445666.
- A scoping review of active, participant centred, digital adverse events following immunization (AEFI) surveillance of WHO approved COVID-19 vaccines: A Canadian immunization Research Network study.Serhan M, Psihogios A, Kabir N, Bota AB, Mithani SS, Smith DP, Zhu DT, Greyson D, Wilson S, Fell D, Top KA, Bettinger JA, Wilson K. Hum Vaccin Immunother. 2024 Dec 31; 2024 Feb 19. PMID: 38374618.
- Sociodemographic correlates of late HIV diagnosis among men who have sex with men (MSM) in Ghana.Aidoo-Frimpong G, Tong G, Akyirem S, Abwoye DN, Nwanaji-Enwerem U, López DJ, Wilton L, Nelson LE. AIDS Care. 2024 Jun; 2024 Mar 9. PMID: 38460152.
- Impact and cost-effectiveness of the 6-month BPaLM regimen for rifampicin-resistant tuberculosis in Moldova: A mathematical modeling analysis.James LP, Klaassen F, Sweeney S, Furin J, Franke MF, Yaesoubi R, Chesov D, Ciobanu N, Codreanu A, Crudu V, Cohen T, Menzies NA. PLoS Med. 2024 May 3; 2024 May 3. PMID: 38701084.
- Modeled estimates of HIV-serodifferent couples in tuberculosis-affected households in four sub-Saharan African countries.Zhang M, Tseng AS, Anguzu G, Barnabas RV, Davis JL, Mujugira A, Flaxman AD, Ross JM. PLOS Glob Public Health. 2024; 2024 May 2. PMID: 38696500.
- Integrated longitudinal multiomics study identifies immune programs associated with acute COVID-19 severity and mortality.Gygi JP, Maguire C, Patel RK, Shinde P, Konstorum A, Shannon CP, Xu L, Hoch A, Jayavelu ND, Haddad EK, Reed EF, Kraft M, McComsey GA, Metcalf JP, Ozonoff A, Esserman D, Cairns CB, Rouphael N, Bosinger SE, Kim-Schulze S, Krammer F, Rosen LB, van Bakel H, Wilson M, Eckalbar WL, Maecker HT, Langelier CR, Steen H, Altman MC, Montgomery RR, Levy O, Melamed E, Pulendran B, Diray-Arce J, Smolen KK, Fragiadakis GK, Becker PM, Sekaly RP, Ehrlich LI, Fourati S, Peters B, Kleinstein SH, Guan L. J Clin Invest. 2024 May 1; 2024 May 1. PMID: 38690733.
- An update on clinical presentation and responses to therapy of patients with hereditary hypophosphatemic rickets with hypercalciuria (HHRH).Zhu Z, Bo-Ran Ho B, Chen A, Amrhein J, Apetrei A, Carpenter TO, Lazaretti-Castro M, Colazo JM, McCrystal Dahir K, Geßner M, Gurevich E, Heier CA, Simmons JH, Hunley TE, Hoppe B, Jacobsen C, Kouri A, Ma N, Majumdar S, Molin A, Nokoff N, Ott SM, Peña HG, Santos F, Tebben P, Topor LS, Deng Y, Bergwitz C. Kidney Int. 2024 May; 2024 Feb 15. PMID: 38364990.
- Using Data-To-Care Strategies to Optimize the HIV Care Continuum in Connecticut: Results From a Randomized Controlled Trial.Machavariani E, Miceli J, Altice FL, Fanfair RN, Speers S, Nichols L, Jenkins H, Villanueva M. J Acquir Immune Defic Syndr. 2024 May 1. PMID: 38324241.
- Social support as a mediator between mental health and stigma among newly HIV-positive men who have sex with men.Zhao Y, Khoshnood K, Sheng Y. Int J STD AIDS. 2024 May; 2024 Feb 5. PMID: 38314565.
- Digital Interventions to Support Lung Cancer Screening: A Systematic Review.Odole IP, Andersen M, Richman IB. Am J Prev Med. 2024 May; 2024 Jan 20. PMID: 38246408.
- The Association of Prescribed Opioids and Incident Cardiovascular Disease.Sung ML, Eden SK, Becker WC, Crystal S, Duncan MS, Gordon KS, Kerns RD, Kundu S, Freiberg M, So-Armah KA, Edelman EJ. J Pain. 2024 May; 2023 Nov 27. PMID: 38029949.
- The full value of immunisation against respiratory syncytial virus for infants younger than 1 year: effects beyond prevention of acute respiratory illness.Feikin DR, Karron RA, Saha SK, Sparrow E, Srikantiah P, Weinberger DM, Zar HJ. Lancet Infect Dis. 2024 May; 2023 Nov 21. PMID: 38000374.
- Prevalence and Correlates of Physical Inactivity Among Individuals with HIV During the First COVID-19 Wave: A Cross-sectional Survey.Harsono D, Deng Y, Chung S, Barakat LA, Friedland G, Villanueva M, Yager JE, Justen M, Edelman EJ. AIDS Behav. 2024 May; 2023 Oct 12. PMID: 37824037.
- Causal interpretation of the hazard ratio in randomized clinical trials.Fay MP, Li F. Clin Trials. 2024 Apr 28; 2024 Apr 28. PMID: 38679930.
- Opportunities for Alcohol-Related Care in the COVID-19 Pandemic and Beyond.Oldfield B, Haque L, Jennifer Edelman E. J Gen Intern Med. 2024 Apr 26; 2024 Apr 26. PMID: 38671202.
- Long COVID Characteristics and Experience: A Descriptive Study from the Yale LISTEN Research Cohort.Sawano M, Wu Y, Shah RM, Zhou T, Arun AS, Khosla P, Kaleem S, Vashist A, Bhattacharjee B, Ding Q, Lu Y, Caraballo C, Warner F, Huang C, Herrin J, Putrino D, Michelsen T, Fisher L, Adinig C, Iwasaki A, Krumholz HM. Am J Med. 2024 Apr 23; 2024 Apr 23. PMID: 38663793.
- Factors Associated with Long COVID Recovery among US Adults.Shah KM, Shah RM, Sawano M, Wu Y, Bishop P, Iwasaki A, Krumholz HM. Am J Med. 2024 Apr 20; 2024 Apr 20. PMID: 38649004.
- Feasibility and utility of a combined nasogastric-tube-and-string-test device for bacteriologic confirmation of pulmonary tuberculosis in young children.Khambati N, Song R, Smith JP, Bijker EM, McCarthy K, Click ES, Mchembere W, Okumu A, Musau S, Okeyo E, Perez-Velez CM, Cain K. Diagn Microbiol Infect Dis. 2024 Apr 18; 2024 Apr 18. PMID: 38657352.
- Host-microbe multiomic profiling reveals age-dependent immune dysregulation associated with COVID-19 immunopathology.Phan HV, Tsitsiklis A, Maguire CP, Haddad EK, Becker PM, Kim-Schulze S, Lee B, Chen J, Hoch A, Pickering H, van Zalm P, Altman MC, Augustine AD, Calfee CS, Bosinger S, Cairns CB, Eckalbar W, Guan L, Jayavelu ND, Kleinstein SH, Krammer F, Maecker HT, Ozonoff A, Peters B, Rouphael N, Montgomery RR, Reed E, Schaenman J, Steen H, Levy O, Diray-Arce J, Langelier CR. Sci Transl Med. 2024 Apr 17; 2024 Apr 17. PMID: 38630846.
- DNA methylation-based telomere length is associated with HIV infection, physical frailty, cancer, and all-cause mortality.Liang X, Aouizerat BE, So-Armah K, Cohen MH, Marconi VC, Xu K, Justice AC. Aging Cell. 2024 Apr 17; 2024 Apr 17. PMID: 38629454.
- Air pollution changes due to COVID-19 lockdowns and attributable mortality changes in four countries.Ma Y, Nobile F, Marb A, Dubrow R, Kinney PL, Peters A, Stafoggia M, Breitner S, Chen K. Environ Int. 2024 Apr 16; 2024 Apr 16. PMID: 38640613.
- A supervised bayesian factor model for the identification of multi-omics signatures.Gygi JP, Konstorum A, Pawar S, Aron E, Kleinstein SH, Guan L. Bioinformatics. 2024 Apr 11; 2024 Apr 11. PMID: 38603606.
- Identifying trusted local sources and predicting behavior change pathways according to COVID-19 vaccination status: Results of a 2022 statewide survey of Alaskan adults.Cameron DB, Grage L, Van Wyck R, Edwards A, Chavez Mapaye J, Cheng A, Garcia G. Vaccine. 2024 Apr 11; 2024 Mar 14. PMID: 38490821.
- Effectiveness of a bivalent mRNA vaccine dose against symptomatic SARS-CoV-2 infection among U.S. Healthcare personnel, September 2022-May 2023.Plumb ID, Briggs Hagen M, Wiegand R, Dumyati G, Myers C, Harland KK, Krishnadasan A, James Gist J, Abedi G, Fleming-Dutra KE, Chea N, Lee JE, Kellogg M, Edmundson A, Britton A, Wilson LE, Lovett SA, Ocampo V, Markus TM, Smithline HA, Hou PC, Lee LC, Mower W, Rwamwejo F, Steele MT, Lim SC, Schrading WA, Chinnock B, Beiser DG, Faine B, Haran JP, Nandi U, Chipman AK, LoVecchio F, Eucker S, Femling J, Fuller M, Rothman RE, Curlin ME, Talan DA, Mohr NM. Vaccine. 2024 Apr 11; 2023 Nov 14. PMID: 37973512.
- Factors associated with tuberculosis treatment initiation among bacteriologically negative individuals evaluated for tuberculosis: an individual patient data meta-analysis.Kim S, Can MH, Agizew TB, Auld AF, Balcells ME, Bjerrum S, Dheda K, Dorman SE, Esmail A, Fielding K, Garcia-Basteiro AL, Hanrahan CF, Kebede W, Kohli M, Luetkemeyer AF, Mita C, Reeve BWP, Silva DR, Sweeney S, Theron G, Trajman A, Vassall A, Warren JL, Yotebieng M, Cohen T, Menzies NA. medRxiv. 2024 Apr 8; 2024 Apr 8. PMID: 38645191.