1999
A Multicomponent Intervention to Prevent Delirium in Hospitalized Older Patients
Inouye S, Bogardus S, Charpentier P, Leo-Summers L, Acampora D, Holford T, Cooney L. A Multicomponent Intervention to Prevent Delirium in Hospitalized Older Patients. New England Journal Of Medicine 1999, 340: 669-676. PMID: 10053175, DOI: 10.1056/nejm199903043400901.Peer-Reviewed Original ResearchConceptsSeverity of deliriumRisk factorsCognitive impairmentRecurrence rateIntervention groupRisk factor intervention strategyHearing impairmentVisual impairmentHospitalized Older PatientsPatients 70 yearsPrevention of deliriumUsual care unitsUsual care groupGeneral medicine serviceEffective treatment strategiesDuration of episodesPrevent DeliriumOlder patientsRate of usePrimary outcomeSleep medicationPoor outcomePrimary preventionPatient's deliriumTeaching hospital
1998
Spontaneous Abortion and Exposure to Electric Blankets and Heated Water Beds
Belanger K, Leaderer B, Hellenbrand K, Holford T, McSharry J, Power M, Bracken M. Spontaneous Abortion and Exposure to Electric Blankets and Heated Water Beds. Epidemiology 1998, 9: 36-42. PMID: 9430266, DOI: 10.1097/00001648-199801000-00009.Peer-Reviewed Original ResearchConceptsElectric blanket useSpontaneous abortionPregnancy lossBlanket useEarly pregnancy lossHeated water bedsTime of conceptionMonth of conceptionWire code categoriesWeeks' gestationProspective studyEarly pregnancyUnadjusted analysesBed useGreater riskPregnancyAbortionDose responseWomenRiskElectric bedElectric blanketExposureSlight increaseGestationSeizures with Fever After Unprovoked Seizures: An Analysis in Children Followed from the Time of a First Febrile Seizure
Berg A, Darefsky A, Holford T, Shinnar S. Seizures with Fever After Unprovoked Seizures: An Analysis in Children Followed from the Time of a First Febrile Seizure. Epilepsia 1998, 39: 77-80. PMID: 9578016, DOI: 10.1111/j.1528-1157.1998.tb01277.x.Peer-Reviewed Original ResearchConceptsFirst febrile seizureFebrile seizuresUnprovoked seizuresFurther seizuresFirst unprovoked seizureRecurrent febrile seizuresCox regression modelBenign febrile seizuresInfluence recurrenceTime-dependent covariatesProspective cohortSecond seizureTreatment decisionsFeverSeizuresSubstantial riskRate ratioYoung childrenChildrenOnsetRegression modelsSmall proportionRiskPredictorsRecurrence
1996
Sex Differences in Survival After Myocardial Infarction in Older Adults: A Community‐Based Approach
Vaccarino V, Krumholz H, de Leon C, Holford T, Seeman T, Horwitz R, Berkman L. Sex Differences in Survival After Myocardial Infarction in Older Adults: A Community‐Based Approach. Journal Of The American Geriatrics Society 1996, 44: 1174-1182. PMID: 8855995, DOI: 10.1111/j.1532-5415.1996.tb01366.x.Peer-Reviewed Original ResearchConceptsMyocardial infarctionMultivariable adjustmentClinical severityRelative riskPsychosocial factorsOlder individualsProspective cohort studyMain outcome measuresDemographic factorsSex differencesHospital complicationsCause mortalityLate mortalityClinical characteristicsCohort studyCT cohortHospital admissionOverall mortalityEarly mortalityElderly ProgramMean agePhysical functionFunctional statusMedical recordsOutcome measuresA TREE‐BASED METHOD OF ANALYSIS FOR PROSPECTIVE STUDIES
ZHANG H, HOLFORD T, BRACKEN M. A TREE‐BASED METHOD OF ANALYSIS FOR PROSPECTIVE STUDIES. Statistics In Medicine 1996, 15: 37-49. PMID: 8614744, DOI: 10.1002/(sici)1097-0258(19960115)15:1<37::aid-sim144>3.0.co;2-0.Peer-Reviewed Original Research
1995
Measurement of Exposure to Environmental Tobacco Smoke in Pregnant Women
O'Connor T, Holford T, Leaderer B, Hammond S, Bracken M. Measurement of Exposure to Environmental Tobacco Smoke in Pregnant Women. American Journal Of Epidemiology 1995, 142: 1315-1321. PMID: 7503052, DOI: 10.1093/oxfordjournals.aje.a117599.Peer-Reviewed Original ResearchConceptsUrine cotinineEnvironmental tobacco smokePregnant womenTobacco smokeWork exposureAir nicotine concentrationsSelf-reported exposurePersonal air monitorsExposure assessment methodsAir nicotineMeasurement of exposureHome exposureCotinineNicotine concentrationsExposure classificationWomenCohen's kappaExposureSpearman rank-order correlation coefficientAir monitorsRank-order correlation coefficientKappaSocial exposureSmokeHigh levelsEXPOSURE TO ELECTROMAGNETIC FIELDS DURING PREGNANCY WITH EMPHASIS ON ELECTRICALLY HEATED BEDS
Bracken M, Belanger K, Hellenbrand K, Dlugosz L, Holford T, McSharry J, Addesso K, Leaderer B. EXPOSURE TO ELECTROMAGNETIC FIELDS DURING PREGNANCY WITH EMPHASIS ON ELECTRICALLY HEATED BEDS. Epidemiology 1995, 6: 263-270. PMID: 7619934, DOI: 10.1097/00001648-199505000-00013.Peer-Reviewed Original ResearchConceptsFetal growth retardationGrowth retardationBed useIntrauterine growth retardationVideo display terminal useDose-response relationPersonal monitorsEMF exposureTime-weighted analysisMonitoring of exposureThird trimesterProspective studyFetal growthWire codesHome measurementsReproductive outcomesHuman studiesPregnancyStudy designVideo display terminalsExposure measuresHours of useMeaningful increaseRiskExposure
1992
The Genetic Epidemiology of Second Primary Breast Cancer*
Bernstein J, Thompson W, Risch N, Holford T. The Genetic Epidemiology of Second Primary Breast Cancer*. American Journal Of Epidemiology 1992, 136: 937-948. PMID: 1456270, DOI: 10.1093/oxfordjournals.aje.a116566.Peer-Reviewed Original ResearchConceptsSecond primary breast cancerPrimary breast cancerContralateral breast cancerFirst primary breast cancerFirst-degree relativesBreast cancerFamily historyOvarian cancerMulti-center population-based case-control studyPopulation-based case-control studyAge-adjusted rate ratioSteroid Hormone StudyBilateral breast cancerEnd Results ProgramRate ratioCase-control studyCorresponding rate ratiosContralateral breastEndometrial cancerProspective studyResults ProgramSecond primaryCohort membersHigh riskHormone StudyRisk Factors Predicting the Incidence of Second Primary Breast Cancer among Women Diagnosed with a First Primary Breast Cancer*
Bernstein J, Thompson W, Risch N, Holford T. Risk Factors Predicting the Incidence of Second Primary Breast Cancer among Women Diagnosed with a First Primary Breast Cancer*. American Journal Of Epidemiology 1992, 136: 925-936. PMID: 1456269, DOI: 10.1093/oxfordjournals.aje.a116565.Peer-Reviewed Original ResearchConceptsFirst primary breast cancerPrimary breast cancerSecond primary breast cancerContralateral breast cancerBreast cancerRisk factorsInitial tumorIncidence rateFirst primaryFirst prospective cohort studyAge-specific incidence ratesDirect patient interviewProspective cohort studySteroid Hormone StudySecond breast cancerEnd Results ProgramBenign breast biopsyProportional hazards modelSpecific risk factorsCohort studyTumor characteristicsLobular carcinomaResults ProgramPatient interviewsTreatment modalities
1991
A prospective longitudinal study of growth in twin gestations compared with growth in singleton pregnancies. II. The fetal limbs.
Reece E, Yarkoni S, Abdalla M, Gabrielli S, Holford T, O'Connor T, Bargar M, Hobbins J. A prospective longitudinal study of growth in twin gestations compared with growth in singleton pregnancies. II. The fetal limbs. Journal Of Ultrasound In Medicine 1991, 10: 445-450. PMID: 1942233, DOI: 10.7863/jum.1991.10.8.445.Peer-Reviewed Original ResearchConceptsTwin gestationsProspective longitudinal studyFetal growthMultiple biometric parametersLongitudinal studySingleton pregnanciesProspective studyTwin APregnancy managementSeparate nomogramsClinical importanceGestationFetal anatomyFemur lengthFetal limbsLong bonesHumerus lengthUlna lengthTibia lengthWeeksBiometric parametersGrowth velocityEvaluation of growthSingletonsPatientsA prospective longitudinal study of growth in twin gestations compared with growth in singleton pregnancies. I. The fetal head.
Reece E, Yarkoni S, Abdalla M, Gabrielli S, Holford T, O'Connor T, Hobbins J. A prospective longitudinal study of growth in twin gestations compared with growth in singleton pregnancies. I. The fetal head. Journal Of Ultrasound In Medicine 1991, 10: 439-443. PMID: 1942232, DOI: 10.7863/jum.1991.10.8.439.Peer-Reviewed Original Research
1987
Estimated fetal weight in the evaluation of growth in twin gestations: a prospective longitudinal study.
Yarkoni S, Reece E, Holford T, O'Connor T, Hobbins J. Estimated fetal weight in the evaluation of growth in twin gestations: a prospective longitudinal study. Obstetrics And Gynecology 1987, 69: 636-9. PMID: 3547216.Peer-Reviewed Original ResearchConceptsProspective longitudinal studyFetal weightBiparietal diameterAbdominal circumferenceFetal weight gainNormal twin pregnanciesWeeks of gestationLongitudinal studyGestational ageHealthy womenTwin gestationsTwin pregnanciesFetal growthTwin AGrowth velocityWeight gainPregnancyMean weightWeeksBiologic variabilityCircumferenceGestationOverall mean weightAgeEvaluation of growthComparison of the logistic and Cox regression models when outcome is determined in all patients after a fixed period of time
Peduzzi P, Holford T, Detre K, Chan Y. Comparison of the logistic and Cox regression models when outcome is determined in all patients after a fixed period of time. Journal Of Clinical Epidemiology 1987, 40: 761-767. PMID: 3597677, DOI: 10.1016/0021-9681(87)90127-5.Peer-Reviewed Original ResearchMeSH KeywordsCoronary DiseaseDrug EvaluationHumansHypolipidemic AgentsMethodsModels, TheoreticalProspective StudiesRegression AnalysisRiskTime Factors
1986
Risk of Late First and Second Trimester Miscarriage After Induced Abortion
Bracken M, Bryce-Buchanan C, Srisuphan W, Holford T, Silten R. Risk of Late First and Second Trimester Miscarriage After Induced Abortion. American Journal Of Perinatology 1986, 3: 84-91. PMID: 3964388, DOI: 10.1055/s-2007-999839.Peer-Reviewed Original ResearchConceptsFirst prenatal visitSecond trimester miscarriagePrivate obstetric practicesLate miscarriagePrenatal visitFirst pregnancySecond pregnancySecond trimesterSubsequent miscarriageTrimester miscarriagePregnancy historyObstetric practiceInduced abortionMiscarriagePregnancyWomenAbortionRiskLate FirstTrimesterCohortVisits