2023
Predictive power of wastewater for nowcasting infectious disease transmission: A retrospective case study of five sewershed areas in Louisville, Kentucky
Klaassen F, Holm R, Smith T, Cohen T, Bhatnagar A, Menzies N. Predictive power of wastewater for nowcasting infectious disease transmission: A retrospective case study of five sewershed areas in Louisville, Kentucky. Environmental Research 2023, 240: 117395. PMID: 37838198, PMCID: PMC10863376, DOI: 10.1016/j.envres.2023.117395.Peer-Reviewed Original ResearchConceptsDeath dataSurveillance dataSARS-CoV-2 casesClinical surveillance dataLow-resource settingsRetrospective case studyInfectious disease transmissionTrue infectionEpidemiologic dataSerosurvey dataDeath reportsTraditional surveillance dataDisease trendsInfectious diseasesWastewater dataDisease transmissionPredictive performance
2022
Reconstructing the course of the COVID-19 epidemic over 2020 for US states and counties: Results of a Bayesian evidence synthesis model
Chitwood MH, Russi M, Gunasekera K, Havumaki J, Klaassen F, Pitzer VE, Salomon JA, Swartwood NA, Warren JL, Weinberger DM, Cohen T, Menzies NA. Reconstructing the course of the COVID-19 epidemic over 2020 for US states and counties: Results of a Bayesian evidence synthesis model. PLOS Computational Biology 2022, 18: e1010465. PMID: 36040963, PMCID: PMC9467347, DOI: 10.1371/journal.pcbi.1010465.Peer-Reviewed Original ResearchConceptsSARS-CoV-2 infectionCOVID-19 casesIncident SARS-CoV-2 infectionCOVID-19 disease burdenSymptomatic COVID-19 casesLocal epidemiological trendsSARS-CoV-2 transmissionBayesian evidence synthesis modelCOVID-19 outcomesEvidence synthesis modelMagnitude of infectionCOVID-19 deathsCumulative incidenceDisease burdenExcess mortalityCase ascertainmentEpidemiological trendsSeroprevalence estimatesUnderlying incidenceUS populationDisease trendsViral transmission dynamicsInfectionEpidemiological driversCOVID-19 epidemic