2022
Personal airborne chemical exposure and epigenetic ageing biomarkers in healthy Chinese elderly individuals: Evidence from mixture approaches
Shi W, Gao X, Cao Y, Chen Y, Cui Q, Deng F, Yang B, Lin E, Fang J, Li T, Tang S, Godri Pollitt K, Shi X. Personal airborne chemical exposure and epigenetic ageing biomarkers in healthy Chinese elderly individuals: Evidence from mixture approaches. Environment International 2022, 170: 107614. PMID: 36375280, DOI: 10.1016/j.envint.2022.107614.Peer-Reviewed Original ResearchConceptsEpigenetic ageing biomarkersPolycyclic aromatic hydrocarbonsOrganic chemical contaminantsVolatile organic compoundsElderly individualsChemical exposureAge-related adverse effectsBayesian kernel machine regression (BKMR) modelsOrganic compoundsAging biomarkersChinese elderly individualsOrganic chemicalsHealthy elderly peopleLinear mixed-effects regression modelsHealthy elderly individualsAirborne chemical exposuresQuantile sum (WQS) regressionPassive samplersNitroaromaticsMixed effects regression modelsEpigenetic biomarkersChemical contaminantsPersonal chemical exposureChlorinated hydrocarbonsChemical mixtures
2021
Exposure to organophosphate esters in elderly people: Relationships of OPE body burdens with indoor air and dust concentrations and food consumption
Hou M, Fang J, Shi Y, Tang S, Dong H, Liu Y, Deng F, Giesy JP, Godri Pollitt KJ, Cai Y, Shi X. Exposure to organophosphate esters in elderly people: Relationships of OPE body burdens with indoor air and dust concentrations and food consumption. Environment International 2021, 157: 106803. PMID: 34365320, DOI: 10.1016/j.envint.2021.106803.Peer-Reviewed Original ResearchConceptsElderly peopleHealth effectsWhole bloodFood frequency questionnaireHealthy elderly peopleHigh blood concentrationsBw/dayDaily total intakeAdverse health effectsHigher consumption frequencyTnBP exposureFrequency questionnaireIndoor dustPotential health effectsUrinary levelsBlood concentrationsDietary exposure pathwaysElderly populationOPE exposureExcretory capacityTotal intakeExposure pathwaysSuitable biomarkersBloodConsumption frequency