2023
Environmental risk scores of persistent organic pollutants associate with higher ALS risk and shorter survival in a new Michigan case/control cohort
Goutman S, Boss J, Jang D, Mukherjee B, Richardson R, Batterman S, Feldman E. Environmental risk scores of persistent organic pollutants associate with higher ALS risk and shorter survival in a new Michigan case/control cohort. Journal Of Neurology Neurosurgery & Psychiatry 2023, 95: 241-248. PMID: 37758454, PMCID: PMC11060633, DOI: 10.1136/jnnp-2023-332121.Peer-Reviewed Original ResearchMeSH KeywordsAmyotrophic Lateral SclerosisEnvironmental PollutantsHumansHydrocarbons, ChlorinatedMichiganPersistent Organic PollutantsRisk FactorsConceptsEnvironmental risk scoreAmyotrophic lateral sclerosis riskPersistent organic pollutantsALS riskInterquartile increaseHigher ALS riskAssociated with ALS riskModify disease riskOrganochlorine pesticidesAssociated with riskRisk reduction strategiesPersistent organic pollutant analysisIndividual persistent organic pollutantsPersistent organic pollutant mixturesHazard ratioDisease riskRisk scoreCase/control cohortEnvironmental exposuresControl participantsGenetic susceptibilityPolychlorinated biphenylsAlpha-hexachlorocyclohexaneOrganic pollutantsMortality rate
2022
Persistent organic pollutant exposure contributes to Black/White differences in leukocyte telomere length in the National Health and Nutrition Examination Survey
Roberts E, Boss J, Mukherjee B, Salerno S, Zota A, Needham B. Persistent organic pollutant exposure contributes to Black/White differences in leukocyte telomere length in the National Health and Nutrition Examination Survey. Scientific Reports 2022, 12: 19960. PMID: 36402910, PMCID: PMC9675834, DOI: 10.1038/s41598-022-24316-0.Peer-Reviewed Original ResearchMeSH KeywordsAdultCross-Sectional StudiesEnvironmental PollutantsHumansLeukocytesNutrition SurveysPersistent Organic PollutantsPolychlorinated BiphenylsTelomereWhite PeopleConceptsNational Health and Nutrition Examination SurveyHealth and Nutrition Examination SurveyPersistent organic pollutantsLeukocyte telomere lengthNutrition Examination SurveyToxic equivalent quotientPolychlorinated biphenylsBlack/white differencesExamination SurveyCross-sectional National Health and Nutrition Examination SurveyNon-Hispanic Black AmericansExposure scoreNon-Hispanic white AmericansSurvey-weighted linear regression modelsIndirect effects of raceAssociated with longer leukocyte telomere lengthSingle-pollutant modelsIndividual persistent organic pollutantsExposure to polychlorinated biphenylsLonger leukocyte telomere lengthSelf-reported racePersistent organic pollutant exposuresBlack AmericansIndividual polychlorinated biphenylOrganic pollutant exposures