2024
Associations of urinary polycyclic aromatic hydrocarbon (PAH) metabolites and their mixture with thyroid hormone concentration during pregnancy in the LIFECODES cohort: A repeated measures study
Park S, Siwakoti R, Ferguson K, Cathey A, Hao W, Cantonwine D, Mukherjee B, McElrath T, Meeker J. Associations of urinary polycyclic aromatic hydrocarbon (PAH) metabolites and their mixture with thyroid hormone concentration during pregnancy in the LIFECODES cohort: A repeated measures study. Environmental Research 2024, 255: 119205. PMID: 38782334, PMCID: PMC11421857, DOI: 10.1016/j.envres.2024.119205.Peer-Reviewed Original ResearchMaternal thyroid hormonesThyroid hormone concentrationsPolycyclic aromatic hydrocarbon metabolitesThyroid hormonesPolycyclic aromatic hydrocarbonsPregnancy outcomesHormone concentrationsFetal sex-specific effectsPAH exposureBayesian kernel machine regressionPotential non-linear associationsHormone physiologyAromatic hydrocarbonsThyroid hormone physiologyPregnancy physiologyFetal growthFetal sexFetal developmentUrinary PAH metabolitesSerial measurementsPregnancyUrinary polycyclic aromatic hydrocarbonsPolycyclic aromatic hydrocarbon exposureStudy visitsThyroid
2019
A repeated measures study of phenol, paraben and Triclocarban urinary biomarkers and circulating maternal hormones during gestation in the Puerto Rico PROTECT cohort
Aker A, Ferguson K, Rosario Z, Mukherjee B, Alshawabkeh A, Calafat A, Cordero J, Meeker J. A repeated measures study of phenol, paraben and Triclocarban urinary biomarkers and circulating maternal hormones during gestation in the Puerto Rico PROTECT cohort. Environmental Health 2019, 18: 28. PMID: 30940137, PMCID: PMC6444601, DOI: 10.1186/s12940-019-0459-5.Peer-Reviewed Original ResearchConceptsUrinary biomarkersAssociated with adverse birth outcomesAdverse birth outcomesPregnant womenBirth outcomesAdverse outcomesSerum hormonesStudy visitsParaben biomarkersThyroid hormonesParaben exposurePercent changeHormoneBiomarker concentrationsMaternal hormonesBiomarkersOutcomesVisitsAssociationExposureGestationRandom interceptPregnancyThyroid
2018
Associations between maternal phenol and paraben urinary biomarkers and maternal hormones during pregnancy: A repeated measures study
Aker A, Johns L, McElrath T, Cantonwine D, Mukherjee B, Meeker J. Associations between maternal phenol and paraben urinary biomarkers and maternal hormones during pregnancy: A repeated measures study. Environment International 2018, 113: 341-349. PMID: 29366524, PMCID: PMC5866216, DOI: 10.1016/j.envint.2018.01.006.Peer-Reviewed Original ResearchConceptsThyroid hormonesAssociated with altered thyroid hormone levelsFetal health outcomesThyroid hormone levelsIQR increaseMultivariate regression analysisGestational ageMultivariate linear regression modelFetal neurodevelopmentPregnant womenFree thyroxinePotential biological mechanismsTime of exposureUrinary biomarkersCohort studyHormone levelsParaben biomarkersTotal triiodothyronineCase-control samplePregnancyBlood samplesTotal thyroxineHormone concentrationsHealth outcomesHormone
2017
Longitudinal Profiles of Thyroid Hormone Parameters in Pregnancy and Associations with Preterm Birth
Johns L, Ferguson K, McElrath T, Mukherjee B, Seely E, Meeker J. Longitudinal Profiles of Thyroid Hormone Parameters in Pregnancy and Associations with Preterm Birth. PLOS ONE 2017, 12: e0169542. PMID: 28060899, PMCID: PMC5217954, DOI: 10.1371/journal.pone.0169542.Peer-Reviewed Original ResearchConceptsRisk of preterm birthPreterm birthNested case-control study of preterm birthThyroid hormonesSubclinical alterationsPregnant womenCase-control study of preterm birthThyroid diseaseOdds of preterm birthOngoing birth cohort studyNested case-control studyStudy of preterm birthAssociated with preterm birthBirth cohort studyTime pointsMultivariate logistic regression modelOverall preterm birthSpontaneous preterm birthWeeks of gestationClinical thyroid diseaseOvert thyroid diseaseThyroid hormone parametersMaternal thyroid hormone concentrationsMaternal thyroid hormonesLogistic regression models
2016
Associations between Repeated Measures of Maternal Urinary Phthalate Metabolites and Thyroid Hormone Parameters during Pregnancy
Johns L, Ferguson K, McElrath T, Mukherjee B, Meeker J. Associations between Repeated Measures of Maternal Urinary Phthalate Metabolites and Thyroid Hormone Parameters during Pregnancy. Environmental Health Perspectives 2016, 124: 1808-1815. PMID: 27152641, PMCID: PMC5089879, DOI: 10.1289/ehp170.Peer-Reviewed Original ResearchConceptsUrinary phthalate metabolitesMaternal urinary phthalate metabolitesThyroid hormone parametersThyroid hormone levelsPregnant womenPhthalate metabolitesStudy visitsHormonal parametersNested case-control study of preterm birthMeasures of urinary phthalate metabolitesHormone levelsCase-control study of preterm birthStudy of preterm birthThyroid hormonesEnvironmental phthalate exposureNested case-control studyNormal thyroid functionLevels of thyroid hormonesThyroid function markersTime pointsCirculating levels of thyroid hormonesTotal thyroid hormonesPreterm birthFetal growthPlasma thyroid hormone levels